clofazimine has been researched along with Opportunistic Infections in 3 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Opportunistic Infections: An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pretty, M | 1 |
| Bifi, J | 1 |
| Radhakrishnan, K | 1 |
| Hashba, H | 1 |
| Dautzenberg, B | 1 |
| Truffot, C | 1 |
| Mignon, A | 1 |
| Rozenbaum, W | 1 |
| Katlama, C | 1 |
| Perronne, C | 1 |
| Parrot, R | 1 |
| Grosset, J | 1 |
| Hudson, V | 1 |
| Cox, F | 1 |
| Taylor, L | 1 |
| Guill, M | 1 |
| Wray, B | 1 |
| Steele, J | 1 |
1 trial available for clofazimine and Opportunistic Infections
| Article | Year |
|---|---|
Rifabutin in combination with clofazimine, isoniazid and ethambutol in the treatment of AIDS patients with infections due to opportunist mycobacteria. Groupe d'Etude et de Traitement des Infections à Mycobacteries Résistantes.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antitubercular Agents; Clofazimine; Drug Therapy, Combina | 1991 |
2 other studies available for clofazimine and Opportunistic Infections
| Article | Year |
|---|---|
Systemic nocardiosis in a lepromatous leprosy patient with type 2 reaction.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Biopsy, Needle; Clofazimine; Drug Therapy, Combination | 2018 |
Pulmonary clofazimine crystals in a child with acquired immunodeficiency syndrome and disseminated Mycobacterium avium-intracellulare infection.
Topics: Acquired Immunodeficiency Syndrome; Child; Clofazimine; Crystallization; Humans; Lung; Male; Mycobac | 1988 |