clofazimine has been researched along with Neoplasms in 4 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cancer is characterized by uncontrolled growth of abnormal cells leading to the formation of tumors." | 1.39 | FOLICation: engineering approved drugs as potential p53-MDM2 interaction inhibitors for cancer therapy. ( Patil, SP, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patil, SP | 1 |
| Singh, DK | 1 |
| Dwivedi, VP | 1 |
| Ranganathan, A | 1 |
| Bishai, WR | 1 |
| Van Kaer, L | 1 |
| Das, G | 1 |
| Levis, W | 1 |
| Rendini, T | 1 |
| Aram, H | 1 |
1 review available for clofazimine and Neoplasms
| Article | Year |
|---|---|
Acquired ichthyosis and related conditions.
Topics: Aged; Cimetidine; Clofazimine; Female; Hodgkin Disease; Humans; Ichthyosis; Lymphoma; Male; Neoplasm | 1984 |
3 other studies available for clofazimine and Neoplasms
| Article | Year |
|---|---|
FOLICation: engineering approved drugs as potential p53-MDM2 interaction inhibitors for cancer therapy.
Topics: Clofazimine; Cyclopentanes; Drug Discovery; Folic Acid; Humans; Imidazoles; Indoles; Models, Molecul | 2013 |
Reply to Levis and Rendini.
Topics: Clofazimine; HIV; Humans; Mycobacterium; Neoplasms | 2017 |
Clofazimine Mechanisms of Action in Mycobacteria, HIV, and Cancer.
Topics: BCG Vaccine; Clofazimine; HIV; Humans; Mycobacterium; Neoplasms; T-Lymphocytes | 2017 |