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clofazimine and Neoplasms

clofazimine has been researched along with Neoplasms in 4 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Cancer is characterized by uncontrolled growth of abnormal cells leading to the formation of tumors."1.39FOLICation: engineering approved drugs as potential p53-MDM2 interaction inhibitors for cancer therapy. ( Patil, SP, 2013)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patil, SP1
Singh, DK1
Dwivedi, VP1
Ranganathan, A1
Bishai, WR1
Van Kaer, L1
Das, G1
Levis, W1
Rendini, T1
Aram, H1

Reviews

1 review available for clofazimine and Neoplasms

ArticleYear
Acquired ichthyosis and related conditions.
    International journal of dermatology, 1984, Volume: 23, Issue:7

    Topics: Aged; Cimetidine; Clofazimine; Female; Hodgkin Disease; Humans; Ichthyosis; Lymphoma; Male; Neoplasm

1984

Other Studies

3 other studies available for clofazimine and Neoplasms

ArticleYear
FOLICation: engineering approved drugs as potential p53-MDM2 interaction inhibitors for cancer therapy.
    Medical hypotheses, 2013, Volume: 81, Issue:6

    Topics: Clofazimine; Cyclopentanes; Drug Discovery; Folic Acid; Humans; Imidazoles; Indoles; Models, Molecul

2013
Reply to Levis and Rendini.
    The Journal of infectious diseases, 2017, 05-01, Volume: 215, Issue:9

    Topics: Clofazimine; HIV; Humans; Mycobacterium; Neoplasms

2017
Clofazimine Mechanisms of Action in Mycobacteria, HIV, and Cancer.
    The Journal of infectious diseases, 2017, 05-01, Volume: 215, Issue:9

    Topics: BCG Vaccine; Clofazimine; HIV; Humans; Mycobacterium; Neoplasms; T-Lymphocytes

2017