clofazimine has been researched along with Necrobiosis Lipoidica in 2 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Necrobiosis Lipoidica: A degenerative disease of the dermal connective tissue characterized by the development of erythematous papules or nodules in the pretibial area. The papules form plaques covered with telangiectatic vessels. More than half of the affected patients have diabetes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty patients, ten suffering from disseminated granuloma anulare and ten from necrobiosis lipoidica, were treated with clofazimine 200 mg p." | 7.67 | [Clofazimine--therapeutic alternative in necrobiosis lipoidica and granuloma anulare]. ( Mensing, H, 1989) |
| "Twenty patients, ten suffering from disseminated granuloma anulare and ten from necrobiosis lipoidica, were treated with clofazimine 200 mg p." | 3.67 | [Clofazimine--therapeutic alternative in necrobiosis lipoidica and granuloma anulare]. ( Mensing, H, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benedix, F | 1 |
| Geyer, A | 1 |
| Lichte, V | 1 |
| Metzler, G | 1 |
| Röcken, M | 1 |
| Strölin, A | 1 |
| Mensing, H | 1 |
2 other studies available for clofazimine and Necrobiosis Lipoidica
| Article | Year |
|---|---|
Response of ulcerated necrobiosis lipoidica to clofazimine.
Topics: Adult; Anti-Inflammatory Agents; Betamethasone; Clofazimine; Female; Humans; Immunosuppressive Agent | 2009 |
[Clofazimine--therapeutic alternative in necrobiosis lipoidica and granuloma anulare].
Topics: Administration, Oral; Adult; Clofazimine; Drug Administration Schedule; Female; Granuloma; Humans; M | 1989 |