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clofazimine and Malacoplakia

clofazimine has been researched along with Malacoplakia in 2 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Malacoplakia: The formation of soft patches on the mucous membrane of a hollow organ, such as the urogenital tract or digestive tract.

Research Excerpts

ExcerptRelevanceReference
"Clofazimine treatment resulted in total remission."1.27Cutaneous malakoplakia. Report of a case. ( Baradad, M; Bombí, JA; Martín, E; Mascaró, JM; Palou, J; Torras, H, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herrero, C1
Torras, H2
Palou, J2
Mascaro, JM2
Baradad, M1
Bombí, JA1
Martín, E1

Other Studies

2 other studies available for clofazimine and Malacoplakia

ArticleYear
Successful treatment of a patient with cutaneous malacoplakia with clofazimine and trimethoprim-sulfamethoxazole.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:5 Pt 1

    Topics: Adult; Clofazimine; Female; Humans; Malacoplakia; Skin Diseases; Trimethoprim, Sulfamethoxazole Drug

1990
Cutaneous malakoplakia. Report of a case.
    Dermatologica, 1988, Volume: 176, Issue:6

    Topics: Adult; Clofazimine; Escherichia coli Infections; Female; Histiocytes; Humans; Immunosuppression Ther

1988