clofazimine has been researched along with Lupus Erythematosus, Chronic Cutaneous in 12 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Its use in other autoimmune diseases has to be considered." | 1.26 | Clofazimine in dermatology. ( Mackey, JP, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (91.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paschos, A | 1 |
| Lehmann, P | 1 |
| C Hofmann, S | 1 |
| Beurey, J | 1 |
| Weber, M | 1 |
| Chaulieu, Y | 1 |
| Jakes, JT | 1 |
| Dubois, EL | 1 |
| Quismorio, FP | 1 |
| Crovato, F | 1 |
| Levi, L | 1 |
| Krivanek, JF | 1 |
| Paver, WK | 2 |
| Dupré, A | 1 |
| Bonafé, JL | 1 |
| Lassère, J | 1 |
| Albarel, N | 1 |
| Christol, B | 1 |
| Krivanek, J | 1 |
| Kossard, S | 2 |
| Cains, G | 1 |
| Mackey, JP | 2 |
| Anderson, R | 2 |
| Zeis, BM | 2 |
| Anderson, IF | 1 |
| Schulz, EJ | 1 |
| Kleeberg, HH | 1 |
| Doherty, E | 1 |
| McColl, I | 1 |
| Ryman, W | 1 |
| Barnes, J | 1 |
1 review available for clofazimine and Lupus Erythematosus, Chronic Cutaneous
| Article | Year |
|---|---|
[Lamprène. New therapeutic indications (excluding leprosy)].
Topics: Acne Vulgaris; Adult; Clofazimine; Female; Humans; Lupus Erythematosus, Discoid; Lupus Vulgaris; Mal | 1982 |
1 trial available for clofazimine and Lupus Erythematosus, Chronic Cutaneous
| Article | Year |
|---|---|
Clofazimine-mediated enhancement of reactive oxidant production by human phagocytes as a possible therapeutic mechanism.
Topics: Adult; Arthritis, Rheumatoid; Clofazimine; Dose-Response Relationship, Drug; Female; Humans; Immunos | 1988 |
10 other studies available for clofazimine and Lupus Erythematosus, Chronic Cutaneous
| Article | Year |
|---|---|
Cutaneous squamous cell carcinoma as a complication of discoid lupus erythematosus.
Topics: Administration, Topical; Adrenal Cortex Hormones; Aged; Antimalarials; Calcineurin Inhibitors; Carci | 2019 |
Antileprosy drugs and lupus erythematosus.
Topics: Clofazimine; Dapsone; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic | 1982 |
Clofazimine in the treatment of annular lupus erythematosus.
Topics: Clofazimine; Female; Humans; Lupus Erythematosus, Discoid; Middle Aged | 1981 |
Further study of the use of clofazimine in discoid lupus erythematosus.
Topics: Clofazimine; Humans; Lupus Erythematosus, Discoid; Time Factors | 1980 |
[Lamprene (Clofazimine) treatment of chronic lupus erythematoides (author's transl)].
Topics: Adult; Chronic Disease; Clofazimine; Dose-Response Relationship, Drug; Drug Evaluation; Female; Huma | 1978 |
Clofazimine (laprene) in the treatment of discoid lupus erythematosus.
Topics: Clofazimine; Humans; Lupus Erythematosus, Discoid | 1976 |
Clofazimine in dermatology.
Topics: Autoimmune Diseases; Clofazimine; Humans; Ireland; Lupus Erythematosus, Discoid; Skin Diseases | 1976 |
Mononuclear leucocyte function in patients with lichen planus and cutaneous lupus erythematosus during chemotherapy with clofazimine.
Topics: Adolescent; Adult; Clofazimine; Female; Humans; Immunity, Cellular; Leukocytes, Mononuclear; Lichen | 1989 |
Autofluorescence of clofazimine in discoid lupus erythematosus.
Topics: Aged; Clofazimine; Female; Fluorescence; Humans; Lupus Erythematosus, Discoid; Pigmentation Disorder | 1987 |
Clofazimine in the treatment of discoid lupus erythematosus.
Topics: Adipose Tissue; Adolescent; Adult; Aged; Clofazimine; Female; Humans; Immunosuppression Therapy; Lup | 1974 |