Page last updated: 2024-10-25

clofazimine and Lung Injury, Acute

clofazimine has been researched along with Lung Injury, Acute in 1 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Research Excerpts

ExcerptRelevanceReference
"Clofazimine (CFZ) has attracted attention due to its anti-inflammatory property in immune diseases as well as infectious diseases."5.72Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice. ( Feng, FK; Gao, Z; Ji, LL; Li, QS; Li, W; Li, XP; Song, L; Wang, GS; Wang, R; Wang, XY; Wang, YN; Xie, H; Xu, HL; Yang, B; Zhang, XY, 2022)
"Clofazimine (CFZ) has attracted attention due to its anti-inflammatory property in immune diseases as well as infectious diseases."1.72Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice. ( Feng, FK; Gao, Z; Ji, LL; Li, QS; Li, W; Li, XP; Song, L; Wang, GS; Wang, R; Wang, XY; Wang, YN; Xie, H; Xu, HL; Yang, B; Zhang, XY, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Yang, B1
Gao, Z1
Li, QS1
Zhang, XY1
Song, L1
Wang, YN1
Wang, XY1
Ji, LL1
Xu, HL1
Xie, H1
Feng, FK1
Li, XP1
Li, W1
Wang, R1
Wang, GS1

Other Studies

1 other study available for clofazimine and Lung Injury, Acute

ArticleYear
Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2022, Volume: 71, Issue:10-11

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Chromatography, Liquid; Clofazimine; COVID-19

2022