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clofazimine and Leukemia, Myeloid

clofazimine has been researched along with Leukemia, Myeloid in 2 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Leukemia, Myeloid: Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.

Research Excerpts

ExcerptRelevanceReference
"Clofazimine is a drug used to treat leprosy."1.34How can we help patients with refractory chronic graft versus host disease- single centre experience. ( Barzal, J; Oborska, S; Rzepecki, P; Sarosiek, T; Szczylik, C, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rzepecki, P1
Barzal, J1
Sarosiek, T1
Oborska, S1
Szczylik, C1
Berg, B1
Brandt, L1

Other Studies

2 other studies available for clofazimine and Leukemia, Myeloid

ArticleYear
How can we help patients with refractory chronic graft versus host disease- single centre experience.
    Neoplasma, 2007, Volume: 54, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clofazimine; Female; Graft vs Host

2007
Syndrome of anaemia, thrombocytopenia and subnormal granulocyte function in elderly patients.
    Scandinavian journal of haematology, 1973, Volume: 10, Issue:3

    Topics: Aged; Alkaline Phosphatase; Anemia; Biopsy, Needle; Bone Marrow; Clofazimine; Humans; Leukemia, Myel

1973