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clofazimine and Leishmaniasis

clofazimine has been researched along with Leishmaniasis in 3 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Leishmaniasis: A disease caused by any of a number of species of protozoa in the genus LEISHMANIA. There are four major clinical types of this infection: cutaneous (Old and New World) (LEISHMANIASIS, CUTANEOUS), diffuse cutaneous (LEISHMANIASIS, DIFFUSE CUTANEOUS), mucocutaneous (LEISHMANIASIS, MUCOCUTANEOUS), and visceral (LEISHMANIASIS, VISCERAL).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Talhari, S1
Cunha, MG1
Barros, ML1
Gadelha, AD1
Evans, AT2
Croft, SL2
Peters, W1
Neal, RA2

Other Studies

3 other studies available for clofazimine and Leishmaniasis

ArticleYear
[Jorge Lobo disease. Study of 22 new cases].
    Medicina cutanea ibero-latino-americana, 1981, Volume: 9, Issue:2

    Topics: Adult; Aged; Brazil; Clofazimine; Dermatomycoses; Electrocoagulation; Female; Humans; Leishmaniasis;

1981
Antileishmanial effects of clofazimine and other antimycobacterial agents.
    Annals of tropical medicine and parasitology, 1989, Volume: 83, Issue:5

    Topics: Administration, Topical; Animals; Antitubercular Agents; Cells, Cultured; Clofazimine; Disease Model

1989
The activity of plumbagin and other electron carriers against Leishmania donovani and Leishmania mexicana amazonensis.
    Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:6

    Topics: Animals; Antiprotozoal Agents; Chlorpromazine; Clofazimine; Electron Transport; Leishmania donovani;

1985