clofazimine has been researched along with Leishmaniasis in 3 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Leishmaniasis: A disease caused by any of a number of species of protozoa in the genus LEISHMANIA. There are four major clinical types of this infection: cutaneous (Old and New World) (LEISHMANIASIS, CUTANEOUS), diffuse cutaneous (LEISHMANIASIS, DIFFUSE CUTANEOUS), mucocutaneous (LEISHMANIASIS, MUCOCUTANEOUS), and visceral (LEISHMANIASIS, VISCERAL).
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Talhari, S | 1 |
Cunha, MG | 1 |
Barros, ML | 1 |
Gadelha, AD | 1 |
Evans, AT | 2 |
Croft, SL | 2 |
Peters, W | 1 |
Neal, RA | 2 |
3 other studies available for clofazimine and Leishmaniasis
Article | Year |
---|---|
[Jorge Lobo disease. Study of 22 new cases].
Topics: Adult; Aged; Brazil; Clofazimine; Dermatomycoses; Electrocoagulation; Female; Humans; Leishmaniasis; | 1981 |
Antileishmanial effects of clofazimine and other antimycobacterial agents.
Topics: Administration, Topical; Animals; Antitubercular Agents; Cells, Cultured; Clofazimine; Disease Model | 1989 |
The activity of plumbagin and other electron carriers against Leishmania donovani and Leishmania mexicana amazonensis.
Topics: Animals; Antiprotozoal Agents; Chlorpromazine; Clofazimine; Electron Transport; Leishmania donovani; | 1985 |