clofazimine has been researched along with Latent Tuberculosis in 3 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Latent Tuberculosis: The dormant form of TUBERCULOSIS where the person shows no obvious symptoms and no sign of the causative agent (Mycobacterium tuberculosis) in the SPUTUM despite being positive for tuberculosis infection skin test.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 1 (33.33) | 2.80 |
Authors | Studies |
---|---|
Karabanovich, G | 1 |
Zemanová, J | 1 |
Smutný, T | 1 |
Székely, R | 1 |
Šarkan, M | 1 |
Centárová, I | 1 |
Vocat, A | 1 |
Pávková, I | 1 |
Čonka, P | 1 |
Němeček, J | 1 |
Stolaříková, J | 1 |
Vejsová, M | 1 |
Vávrová, K | 1 |
Klimešová, V | 1 |
Hrabálek, A | 1 |
Pávek, P | 1 |
Cole, ST | 2 |
Mikušová, K | 1 |
Roh, J | 1 |
Chew, R | 1 |
Woods, ML | 1 |
Zhang, M | 1 |
Sala, C | 1 |
Hartkoorn, RC | 1 |
Dhar, N | 1 |
Mendoza-Losana, A | 1 |
3 other studies available for clofazimine and Latent Tuberculosis
Article | Year |
---|---|
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Mu | 2016 |
Multibacillary Mid-Borderline Leprosy with Type 1 Lepra Reaction and Concurrent Latent Tuberculosis.
Topics: Abattoirs; Anti-Inflammatory Agents; Antitubercular Agents; Clofazimine; Dapsone; Diagnosis, Differe | 2021 |
Streptomycin-starved Mycobacterium tuberculosis 18b, a drug discovery tool for latent tuberculosis.
Topics: Acetamides; Amino Acid Sequence; Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Dise | 2012 |