Page last updated: 2024-10-25

clofazimine and Latent Tuberculosis

clofazimine has been researched along with Latent Tuberculosis in 3 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Latent Tuberculosis: The dormant form of TUBERCULOSIS where the person shows no obvious symptoms and no sign of the causative agent (Mycobacterium tuberculosis) in the SPUTUM despite being positive for tuberculosis infection skin test.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Karabanovich, G1
Zemanová, J1
Smutný, T1
Székely, R1
Šarkan, M1
Centárová, I1
Vocat, A1
Pávková, I1
Čonka, P1
Němeček, J1
Stolaříková, J1
Vejsová, M1
Vávrová, K1
Klimešová, V1
Hrabálek, A1
Pávek, P1
Cole, ST2
Mikušová, K1
Roh, J1
Chew, R1
Woods, ML1
Zhang, M1
Sala, C1
Hartkoorn, RC1
Dhar, N1
Mendoza-Losana, A1

Other Studies

3 other studies available for clofazimine and Latent Tuberculosis

ArticleYear
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
    Journal of medicinal chemistry, 2016, Mar-24, Volume: 59, Issue:6

    Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Mu

2016
Multibacillary Mid-Borderline Leprosy with Type 1 Lepra Reaction and Concurrent Latent Tuberculosis.
    The American journal of tropical medicine and hygiene, 2021, 10-25, Volume: 106, Issue:2

    Topics: Abattoirs; Anti-Inflammatory Agents; Antitubercular Agents; Clofazimine; Dapsone; Diagnosis, Differe

2021
Streptomycin-starved Mycobacterium tuberculosis 18b, a drug discovery tool for latent tuberculosis.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:11

    Topics: Acetamides; Amino Acid Sequence; Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Dise

2012