Page last updated: 2024-10-25

clofazimine and Jorge Lobo Disease

clofazimine has been researched along with Jorge Lobo Disease in 3 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Research Excerpts

ExcerptRelevanceReference
"Lobomycosis or lacaziosis is a chronic granulomatous fungal infection caused by Lacazia loboi."1.48Lobomycosis: a therapeutic challenge. ( Aguilar, CR; Araújo, MG; Cirilo, NS; Guedes, ACM; Santos, SNMBD, 2018)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Pech-Ortiz, L1
Maya-Aranda, S1
Hernández-Castro, R1
Xicohtencatl-Cortes, J1
Tirado-Sánchez, A1
Bonifaz, A1
Beltrame, A1
Danesi, P1
Farina, C1
Orza, P1
Perandin, F1
Zanardello, C1
Rodari, P1
Staffolani, S1
Bisoffi, Z1
Araújo, MG1
Cirilo, NS1
Santos, SNMBD1
Aguilar, CR1
Guedes, ACM1

Other Studies

3 other studies available for clofazimine and Jorge Lobo Disease

ArticleYear
Lacaziosis (Lobomycosis) From Southern Mexico: A Case Confirmed by Molecular Biology.
    Mycopathologia, 2020, Volume: 185, Issue:4

    Topics: Adult; Antifungal Agents; Clofazimine; Dermatomycoses; Drug Combinations; Ear; Ear Auricle; Fibrosis

2020
Case Report: Molecular Confirmation of Lobomycosis in an Italian Traveler Acquired in the Amazon Region of Venezuela.
    The American journal of tropical medicine and hygiene, 2017, Volume: 97, Issue:6

    Topics: Antifungal Agents; Clofazimine; Humans; Italy; Itraconazole; Lacazia; Lobomycosis; Male; Middle Aged

2017
Lobomycosis: a therapeutic challenge.
    Anais brasileiros de dermatologia, 2018, Volume: 93, Issue:2

    Topics: Adult; Antifungal Agents; Biopsy; Clofazimine; Cryotherapy; Diagnosis, Differential; Ear Diseases; H

2018