clofazimine has been researched along with Johne Disease in 7 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhillon, AS | 1 |
| Johnston, EL | 1 |
| Sanderson, JD | 1 |
| Savarino, E | 1 |
| Bertani, L | 1 |
| Ceccarelli, L | 1 |
| Bodini, G | 1 |
| Zingone, F | 1 |
| Buda, A | 1 |
| Facchin, S | 1 |
| Lorenzon, G | 1 |
| Marchi, S | 1 |
| Marabotto, E | 1 |
| De Bortoli, N | 1 |
| Savarino, V | 1 |
| Costa, F | 1 |
| Blandizzi, C | 1 |
| Kuenstner, JT | 1 |
| Lipton, JE | 1 |
| Barash, DP | 1 |
| Gitlin, L | 1 |
| Biesecker, J | 1 |
| Chamberlin, W | 1 |
| Hermon-Taylor, J | 1 |
1 review available for clofazimine and Johne Disease
| Article | Year |
|---|---|
Antimicrobial treatment with the fixed-dose antibiotic combination RHB-104 for Mycobacterium avium subspecies paratuberculosis in Crohn's disease: pharmacological and clinical implications.
Topics: Animals; Anti-Bacterial Agents; Clarithromycin; Clofazimine; Crohn Disease; Drug Combinations; Human | 2019 |
6 other studies available for clofazimine and Johne Disease
| Article | Year |
|---|---|
A Case of Unusual Ileal Discoloration.
Topics: Clofazimine; Crohn Disease; Histiocytosis; Humans; Ileal Diseases; Leprostatic Agents; Male; Mycobac | 2018 |
The Australian antibiotic trial in Crohn's disease: alternative conclusions from the same study.
Topics: Anti-Bacterial Agents; Clarithromycin; Clofazimine; Crohn Disease; Drug Therapy, Combination; Humans | 2007 |
Flawed Australian CD study does not end MAP controversy.
Topics: Anti-Bacterial Agents; Clarithromycin; Clofazimine; Crohn Disease; Drug Therapy, Combination; Humans | 2007 |
Australian Crohn's antibiotic study opens new horizons.
Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Clarithromycin; Clofazimine; Crohn Disease; Drug Ther | 2007 |
Importance of the Australian Crohn's disease antibiotic study.
Topics: Anti-Bacterial Agents; Clarithromycin; Clofazimine; Crohn Disease; Data Interpretation, Statistical; | 2007 |
Treatment with drugs active against Mycobacterium avium subspecies paratuberculosis can heal Crohn's disease: more evidence for a neglected public health tragedy.
Topics: Clarithromycin; Clofazimine; Crohn Disease; Drug Resistance, Bacterial; Drug Therapy, Combination; H | 2002 |