clofazimine has been researched along with Intestinal Diseases in 13 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a chronic case of nodular vasculitis that responded to oral clofazimine 300 mg daily." | 7.78 | Clofazimine-induced enteropathy in treatment-resistant nodular vasculitis. ( Hill, P; Kelly, R; Kieu, V; Williams, R, 2012) |
| "Clofazimine enterophathy is a serious complication of clofazimine when used at high doses for treatment of type 2 lepra or or erythema nodosum leprosum." | 7.75 | [Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy]. ( Gómez, Y; López, F; Pinto, R; Rodríguez, G, 2009) |
| "A 46-year-old woman with widespread prurigo nodularis was treated with 300 mg clofazimine a day for six months." | 7.66 | Small bowel deposition of crystals associated with the use of clofazimine (Lamprene) in the treatment of prurigo nodularis. ( Belaube, P; Boutboul, R; Devaux, J; Pizzi, M; Privat, Y, 1983) |
| "We report a chronic case of nodular vasculitis that responded to oral clofazimine 300 mg daily." | 3.78 | Clofazimine-induced enteropathy in treatment-resistant nodular vasculitis. ( Hill, P; Kelly, R; Kieu, V; Williams, R, 2012) |
| "Clofazimine enterophathy is a serious complication of clofazimine when used at high doses for treatment of type 2 lepra or or erythema nodosum leprosum." | 3.75 | [Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy]. ( Gómez, Y; López, F; Pinto, R; Rodríguez, G, 2009) |
| "A 46-year-old woman with widespread prurigo nodularis was treated with 300 mg clofazimine a day for six months." | 3.66 | Small bowel deposition of crystals associated with the use of clofazimine (Lamprene) in the treatment of prurigo nodularis. ( Belaube, P; Boutboul, R; Devaux, J; Pizzi, M; Privat, Y, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Oberoi, A | 1 |
| Poojari, V | 1 |
| Shah, I | 1 |
| Rodríguez, G | 1 |
| Pinto, R | 1 |
| López, F | 1 |
| Gómez, Y | 1 |
| Kieu, V | 1 |
| Williams, R | 1 |
| Hill, P | 1 |
| Kelly, R | 1 |
| Belaube, P | 2 |
| Devaux, J | 3 |
| Pizzi, M | 2 |
| Boutboul, R | 3 |
| Privat, Y | 2 |
| Pariente, EA | 1 |
| Le Treut, YP | 1 |
| de Micco, C | 1 |
| Bricot, R | 1 |
| Galland, MC | 1 |
| Hameed, A | 1 |
| Beach, FX | 1 |
| Kennedy, RH | 1 |
| Barry, RE | 1 |
| Levine, S | 1 |
| Saltzman, A | 1 |
| Davy, C | 1 |
| Riveau, E | 1 |
| Bousquet, JC | 1 |
| Curet, P | 1 |
| Vayre, P | 3 |
| Cortez, A | 4 |
| Grellet, J | 1 |
| Venencie, PY | 2 |
| Orieux, G | 2 |
| Jost, JL | 2 |
| Chomette, G | 3 |
| Puissant, A | 2 |
| Debbasch, L | 1 |
| Karkouche, B | 1 |
13 other studies available for clofazimine and Intestinal Diseases
| Article | Year |
|---|---|
A Rare Case of Clofazimine-induced Pigmentary Enteropathy.
Topics: Clofazimine; Digestive System Abnormalities; Humans; Intestinal Diseases; Pigmentation | 2021 |
[Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy].
Topics: Abdominal Pain; Adult; Arthritis, Rheumatoid; Child; Child, Preschool; Clofazimine; Constipation; Di | 2009 |
Clofazimine-induced enteropathy in treatment-resistant nodular vasculitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; Clofazimine; Drug Therapy, Co | 2012 |
Small bowel deposition of crystals associated with the use of clofazimine (Lamprene) in the treatment of prurigo nodularis.
Topics: Clofazimine; Crystallization; Female; Humans; Intestinal Diseases; Middle Aged; Prurigo | 1983 |
[Drug-induced enteropathies].
Topics: Clofazimine; Humans; Intestinal Diseases | 1982 |
[Clofazimine-induced enteropathy: a case report with ultrastructural study (author's transl)].
Topics: Adult; Clofazimine; Female; Humans; Ileum; Intestinal Diseases; Intestine, Small; Jejunum; Male; Mid | 1982 |
[Deposits of crystals in the mucous membrane of the small intestine during treatment with clofazimine].
Topics: Celiac Disease; Clofazimine; Crystallization; Female; Humans; Intestinal Diseases; Intestinal Mucosa | 1982 |
A case of clofazimine enteropathy.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Fatal Outcome; Humans; Intestinal | 1998 |
Clofazimine enteropathy: possible relation to Peyer's patches.
Topics: Animals; Clofazimine; Female; Granuloma; Intestinal Diseases; Lymph Nodes; Male; Mice; Peyer's Patch | 1986 |
[Small intestine transit anomalies in a patient with chronic abdominal pain and treated for Hansen's disease].
Topics: Abdomen; Chronic Disease; Clofazimine; Female; Gastrointestinal Motility; Humans; Intestinal Disease | 1986 |
Clofazimine enteropathy.
Topics: Clofazimine; Female; Humans; Intestinal Diseases; Middle Aged | 1986 |
[Enteropathy caused by clofazimine].
Topics: Clofazimine; Female; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Lymph Nodes; | 1986 |
[Clofazimine enteropathy. Apropos of a new anatomoclinical case].
Topics: Clofazimine; Female; Humans; Intestinal Diseases; Intestinal Mucosa; Lymph Nodes; Mesentery; Middle | 1985 |