clofazimine has been researched along with Incontinentia Pigmenti Achromians in 19 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the expression of several cell adhesion and lymphocyte activation molecules in erythema dyschromicum perstans lesions, and to evaluate the effect of clofazimine therapy on the expression of these molecules." | 7.69 | Involvement of cell adhesion and activation molecules in the pathogenesis of erythema dyschromicum perstans (ashy dermatitis). The effect of clofazimine therapy. ( Baranda, L; Cortes-Franco, R; Gonzalez-Amaro, R; Moncada, B; Portales-Perez, DP; Torres-Alvarez, B, 1997) |
| "To assess the expression of several cell adhesion and lymphocyte activation molecules in erythema dyschromicum perstans lesions, and to evaluate the effect of clofazimine therapy on the expression of these molecules." | 3.69 | Involvement of cell adhesion and activation molecules in the pathogenesis of erythema dyschromicum perstans (ashy dermatitis). The effect of clofazimine therapy. ( Baranda, L; Cortes-Franco, R; Gonzalez-Amaro, R; Moncada, B; Portales-Perez, DP; Torres-Alvarez, B, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Chavhan, SD | 1 |
| Jawade, S | 1 |
| Bhangale, NP | 1 |
| Abraham, P | 1 |
| Joshi, A | 1 |
| Desai, D | 1 |
| Dhillon, AS | 1 |
| Johnston, EL | 1 |
| Sanderson, JD | 1 |
| Raftopoulos, SC | 1 |
| Fermoyle, S | 1 |
| BROWNE, SG | 1 |
| McDougall, AC | 1 |
| Jones, RL | 1 |
| Granstein, RD | 1 |
| Sober, AJ | 1 |
| Moore, VJ | 1 |
| Kaufman, AC | 1 |
| Greene, CE | 1 |
| Rakich, PM | 1 |
| Weigner, DD | 1 |
| Krop, LC | 1 |
| Johnson, DP | 1 |
| Baranda, L | 1 |
| Torres-Alvarez, B | 1 |
| Cortes-Franco, R | 1 |
| Moncada, B | 1 |
| Portales-Perez, DP | 1 |
| Gonzalez-Amaro, R | 1 |
| Hameed, A | 1 |
| Beach, FX | 1 |
| Kennedy, RH | 1 |
| Barry, RE | 1 |
| Wålinder, PE | 1 |
| Gip, L | 1 |
| Stempa, M | 1 |
| Gallais, V | 1 |
| Lacour, JP | 1 |
| Ortonne, JP | 1 |
| Job, CK | 1 |
| Yoder, L | 1 |
| Jacobson, RR | 1 |
| Hastings, RC | 1 |
| Patki, AH | 1 |
| Jadhav, VH | 1 |
| Mehta, JM | 1 |
| Zhang, X | 2 |
| Langford, A | 2 |
| Gelderblom, H | 2 |
| Reichart, P | 1 |
| Pohle, HD | 1 |
| Reichart, PA | 1 |
| Kossard, S | 1 |
| Doherty, E | 1 |
| McColl, I | 1 |
| Ryman, W | 1 |
2 reviews available for clofazimine and Incontinentia Pigmenti Achromians
| Article | Year |
|---|---|
Drug- and heavy metal--induced hyperpigmentation.
Topics: Adrenocorticotropic Hormone; Amiodarone; Antimalarials; Antineoplastic Agents; Argyria; Arsenic; Bis | 1981 |
[Cutaneous pigmentation disorders in human immunodeficiency virus infection].
Topics: Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; Antiviral Agents; Bleomycin; Clofazimine; | 1992 |
17 other studies available for clofazimine and Incontinentia Pigmenti Achromians
| Article | Year |
|---|---|
Clofazimine induced pigmentation in leprosy patches.
Topics: Clofazimine; Humans; Leprosy; Pigmentation; Pigmentation Disorders | 2022 |
Clofazimine-related duodenal pigmentation.
Topics: Clofazimine; Duodenum; Humans; Pigmentation; Pigmentation Disorders | 2021 |
A Case of Unusual Ileal Discoloration.
Topics: Clofazimine; Crohn Disease; Histiocytosis; Humans; Ileal Diseases; Leprostatic Agents; Male; Mycobac | 2018 |
An unusual cause of small-intestine mucosal pigmentation.
Topics: Adult; Clofazimine; Duodenal Diseases; Endoscopy, Digestive System; Erythema Nodosum; Humans; Lepros | 2011 |
RED AND BLACK PIGMENTATION DEVELOPING DURING TREATMENT OF LEPROSY WITH 'B 663'.
Topics: Antitubercular Agents; Black People; Clofazimine; Drug Therapy; Humans; Leprosy; Pathology; Phenazin | 1965 |
Intra-neural ceroid-like pigment following the treatment of lepromatous leprosy with clofazimine (B663; Lamprene).
Topics: Adult; Ceroid; Clofazimine; Dapsone; Drug Therapy, Combination; Histocytochemistry; Humans; Leprosy; | 1981 |
A review of side-effects experienced by patients taking clofazimine.
Topics: Clofazimine; Digestive System; Eye Diseases; Humans; Leprosy; Pigmentation Disorders; Time Factors | 1983 |
Treatment of localized Mycobacterium avium complex infection with clofazimine and doxycycline in a cat.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clofazimine; Doxycycline; Granuloma; Leprostatic | 1995 |
Cutaneous disease and drug reactions in HIV infection.
Topics: Clofazimine; Drug Eruptions; HIV Infections; Humans; Pigmentation Disorders; Skin Diseases | 1993 |
Involvement of cell adhesion and activation molecules in the pathogenesis of erythema dyschromicum perstans (ashy dermatitis). The effect of clofazimine therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Cell Adhesion Molecules; Clofazimine; Erythem | 1997 |
A case of clofazimine enteropathy.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Fatal Outcome; Humans; Intestinal | 1998 |
Corneal changes in patients treated with clofazimine.
Topics: Adult; Aged; Clofazimine; Cornea; Corneal Diseases; Humans; Middle Aged; Pigmentation Disorders | 1976 |
Skin pigmentation from clofazimine therapy in leprosy patients: a reappraisal.
Topics: Aged; Aged, 80 and over; Clofazimine; Drug Eruptions; Female; Humans; Leprosy, Lepromatous; Male; Ne | 1990 |
A study of dermatological conditions in leprosy in-patients.
Topics: Clofazimine; Drug Eruptions; Female; Humans; Inpatients; Keratosis; Leprosy; Male; Pigmentation Diso | 1989 |
Ultrastructural findings in oral hyperpigmentation of HIV-infected patients.
Topics: Adult; Cheek; Clofazimine; Female; Gingival Diseases; HIV Infections; Humans; Ketoconazole; Male; Me | 1989 |
Oral hyperpigmentation in HIV-infected patients.
Topics: Adult; Clofazimine; Connective Tissue; Epithelium; Female; HIV Seropositivity; Humans; Ketoconazole; | 1989 |
Autofluorescence of clofazimine in discoid lupus erythematosus.
Topics: Aged; Clofazimine; Female; Fluorescence; Humans; Lupus Erythematosus, Discoid; Pigmentation Disorder | 1987 |