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clofazimine and Immune System Diseases

clofazimine has been researched along with Immune System Diseases in 1 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Immune System Diseases: Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both.

Research Excerpts

ExcerptRelevanceReference
"Treatment with clofazimine resulted in a marked improvement of the lesions."1.27Malignant pyoderma. Report of a case associated with a disorder of the immune system. ( Aram, H, 1985)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aram, H1

Other Studies

1 other study available for clofazimine and Immune System Diseases

ArticleYear
Malignant pyoderma. Report of a case associated with a disorder of the immune system.
    Dermatologica, 1985, Volume: 171, Issue:2

    Topics: Adult; Clofazimine; Diagnosis, Differential; Humans; Immune System Diseases; Male; Middle Aged; Pyod

1985