clofazimine has been researched along with Ichthyosis in 4 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Ichthyosis: Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clofazimine is a valuable drug which is used worldwide in the treatment of leprosy." | 7.66 | Clofazimine-induced ichthyosis and its treatment. ( Caver, CV, 1982) |
| "Clofazimine is a valuable drug which is used worldwide in the treatment of leprosy." | 3.66 | Clofazimine-induced ichthyosis and its treatment. ( Caver, CV, 1982) |
| " The common side effect in all cases consisted of red and dark skin pigmentation of varying intensity occuring within 10 weeks of the commencement of therapy." | 1.26 | Side effects of clofazimine therapy. ( Iyer, GG; Ramu, G, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aram, H | 1 |
| Caver, CV | 1 |
| Bharadwaj, VP | 1 |
| Sritharan, V | 1 |
| Venkatesan, K | 1 |
| Girdhar, A | 1 |
| Ramu, G | 2 |
| Iyer, GG | 1 |
1 review available for clofazimine and Ichthyosis
| Article | Year |
|---|---|
Acquired ichthyosis and related conditions.
Topics: Aged; Cimetidine; Clofazimine; Female; Hodgkin Disease; Humans; Ichthyosis; Lymphoma; Male; Neoplasm | 1984 |
1 trial available for clofazimine and Ichthyosis
| Article | Year |
|---|---|
Vitamin A levels of ichthyotic and non-ichthyotic skin and plasma of leprosy patients with and without clofazimine therapy.
Topics: Clofazimine; Humans; Ichthyosis; Leprosy; Skin; Vitamin A | 1982 |
2 other studies available for clofazimine and Ichthyosis
| Article | Year |
|---|---|
Clofazimine-induced ichthyosis and its treatment.
Topics: Clofazimine; Humans; Ichthyosis; Leprosy | 1982 |
Side effects of clofazimine therapy.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Female; Humans; Ichthyosis; Isoniazid; Leprosy; Male; Skin | 1976 |