clofazimine has been researched along with Hyperpigmentation in 9 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Hyperpigmentation: Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (11.11) | 18.2507 |
2000's | 1 (11.11) | 29.6817 |
2010's | 6 (66.67) | 24.3611 |
2020's | 1 (11.11) | 2.80 |
Authors | Studies |
---|---|
Fischer, JL | 1 |
Tolisano, AM | 1 |
Strausborger, SL | 1 |
Lewin-Smith, MR | 1 |
Olivier, KN | 1 |
Riley, CA | 1 |
Rato, M | 1 |
Monteiro, AF | 1 |
Aranha, J | 1 |
Tavares, E | 1 |
Nguyen, K | 1 |
Khachemoune, A | 1 |
Bishnoi, A | 1 |
Chatterjee, D | 1 |
Narang, T | 2 |
Dogra, S | 2 |
Khardenavis, S | 1 |
Deshpande, A | 1 |
Sakia, UN | 1 |
Levis, WR | 1 |
Spencer, TI | 1 |
Ladizinski, B | 1 |
Nenoff, P | 1 |
Uhlemann, R | 1 |
Grünewald, T | 1 |
Nenning, H | 1 |
Grunewald, S | 1 |
Paasch, U | 1 |
Gallais, V | 1 |
Lacour, JP | 1 |
Ortonne, JP | 1 |
2 reviews available for clofazimine and Hyperpigmentation
Article | Year |
---|---|
Ashy dermatosis: a review.
Topics: Anti-Inflammatory Agents; Clofazimine; Disease Management; Humans; Hyperpigmentation; Skin; Terminol | 2019 |
[Cutaneous pigmentation disorders in human immunodeficiency virus infection].
Topics: Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; Antiviral Agents; Bleomycin; Clofazimine; | 1992 |
7 other studies available for clofazimine and Hyperpigmentation
Article | Year |
---|---|
A Novel Case of Clofazimine-Induced Purple Nasal Mucosal Discoloration.
Topics: Aged; Anti-Bacterial Agents; Clofazimine; Female; Humans; Hyperpigmentation; Nasal Mucosa | 2021 |
Ashy dermatosis with involvement of mucous membranes.
Topics: Anti-Inflammatory Agents; Biopsy; Clofazimine; Erythema; Female; Humans; Hyperpigmentation; Middle A | 2017 |
Image Gallery: Clofazimine-induced hyperpigmentation of leprosy plaques.
Topics: Clofazimine; Drug Therapy, Combination; Face; Humans; Hyperpigmentation; Leprosy; Male; Skin | 2019 |
Borderline tuberculoid leprosy with type 1/reversal reaction.
Topics: Clofazimine; Facial Nerve Diseases; Facial Paralysis; Humans; Hyperpigmentation; Leprostatic Agents; | 2014 |
Persistent serpentine supravenous hyperpigmented eruption in lepromatous leprosy after minocycline.
Topics: Adult; Anti-Bacterial Agents; Clofazimine; Humans; Hyperpigmentation; Leprostatic Agents; Leprosy, L | 2015 |
Minocycline is effective and cosmetically preferred to clofazimine by leprosy patients in New York.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Hyperpigmentation; Leprostatic Agents; Lepr | 2010 |
[Atypical mycobacteriosis of the skin caused by Mycobacterium abscessus in an immunocompetent woman].
Topics: Antitubercular Agents; Biopsy; Buruli Ulcer; Clofazimine; Drug Therapy, Combination; Female; Follow- | 2007 |