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clofazimine and Hyperpigmentation

clofazimine has been researched along with Hyperpigmentation in 9 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Hyperpigmentation: Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Fischer, JL1
Tolisano, AM1
Strausborger, SL1
Lewin-Smith, MR1
Olivier, KN1
Riley, CA1
Rato, M1
Monteiro, AF1
Aranha, J1
Tavares, E1
Nguyen, K1
Khachemoune, A1
Bishnoi, A1
Chatterjee, D1
Narang, T2
Dogra, S2
Khardenavis, S1
Deshpande, A1
Sakia, UN1
Levis, WR1
Spencer, TI1
Ladizinski, B1
Nenoff, P1
Uhlemann, R1
Grünewald, T1
Nenning, H1
Grunewald, S1
Paasch, U1
Gallais, V1
Lacour, JP1
Ortonne, JP1

Reviews

2 reviews available for clofazimine and Hyperpigmentation

ArticleYear
Ashy dermatosis: a review.
    Dermatology online journal, 2019, May-15, Volume: 25, Issue:5

    Topics: Anti-Inflammatory Agents; Clofazimine; Disease Management; Humans; Hyperpigmentation; Skin; Terminol

2019
[Cutaneous pigmentation disorders in human immunodeficiency virus infection].
    Annales de dermatologie et de venereologie, 1992, Volume: 119, Issue:6-7

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; Antiviral Agents; Bleomycin; Clofazimine;

1992

Other Studies

7 other studies available for clofazimine and Hyperpigmentation

ArticleYear
A Novel Case of Clofazimine-Induced Purple Nasal Mucosal Discoloration.
    JAMA otolaryngology-- head & neck surgery, 2021, 11-01, Volume: 147, Issue:11

    Topics: Aged; Anti-Bacterial Agents; Clofazimine; Female; Humans; Hyperpigmentation; Nasal Mucosa

2021
Ashy dermatosis with involvement of mucous membranes.
    Anais brasileiros de dermatologia, 2017, Volume: 92, Issue:5 Suppl 1

    Topics: Anti-Inflammatory Agents; Biopsy; Clofazimine; Erythema; Female; Humans; Hyperpigmentation; Middle A

2017
Image Gallery: Clofazimine-induced hyperpigmentation of leprosy plaques.
    The British journal of dermatology, 2019, Volume: 181, Issue:4

    Topics: Clofazimine; Drug Therapy, Combination; Face; Humans; Hyperpigmentation; Leprosy; Male; Skin

2019
Borderline tuberculoid leprosy with type 1/reversal reaction.
    BMJ case reports, 2014, Jan-30, Volume: 2014

    Topics: Clofazimine; Facial Nerve Diseases; Facial Paralysis; Humans; Hyperpigmentation; Leprostatic Agents;

2014
Persistent serpentine supravenous hyperpigmented eruption in lepromatous leprosy after minocycline.
    Leprosy review, 2015, Volume: 86, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Clofazimine; Humans; Hyperpigmentation; Leprostatic Agents; Leprosy, L

2015
Minocycline is effective and cosmetically preferred to clofazimine by leprosy patients in New York.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:8

    Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Hyperpigmentation; Leprostatic Agents; Lepr

2010
[Atypical mycobacteriosis of the skin caused by Mycobacterium abscessus in an immunocompetent woman].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2007, Volume: 58, Issue:12

    Topics: Antitubercular Agents; Biopsy; Buruli Ulcer; Clofazimine; Drug Therapy, Combination; Female; Follow-

2007