clofazimine has been researched along with Hodgkin Disease in 2 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Hodgkin Disease: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The term "granulomatous slack skin" (GSS) was introduced by Ackerman for a disease first described by Convit et al." | 2.39 | ["Granulomatous slack skin"--cutaneous elastolytic lymphoma]. ( Mielke, V; Simon, M; Staib, G; Sterry, W; Tacke, J; von den Driesch, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aram, H | 1 |
| von den Driesch, P | 1 |
| Mielke, V | 1 |
| Simon, M | 1 |
| Staib, G | 1 |
| Tacke, J | 1 |
| Sterry, W | 1 |
2 reviews available for clofazimine and Hodgkin Disease
| Article | Year |
|---|---|
Acquired ichthyosis and related conditions.
Topics: Aged; Cimetidine; Clofazimine; Female; Hodgkin Disease; Humans; Ichthyosis; Lymphoma; Male; Neoplasm | 1984 |
["Granulomatous slack skin"--cutaneous elastolytic lymphoma].
Topics: Biopsy; Clofazimine; Combined Modality Therapy; Ehlers-Danlos Syndrome; Elastic Tissue; Etretinate; | 1994 |