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clofazimine and Hemoptysis

clofazimine has been researched along with Hemoptysis in 2 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Hemoptysis: Expectoration or spitting of blood originating from any part of the RESPIRATORY TRACT, usually from hemorrhage in the lung parenchyma (PULMONARY ALVEOLI) and the BRONCHIAL ARTERIES.

Research Excerpts

ExcerptRelevanceReference
"A patient of lepromatous leprosy, who received a high dose of clofazimine as part of multidrug therapy, for chronic erythema nodosum leprosum (ENL) had frequent 'haemoptysis'."3.68Red discoloration of the sputum by clofazimine simulating haemoptysis--a case report. ( Chauhan, SL; Girdhar, A; Girdhar, BK; Malaviya, GN; Venkatesan, K, 1992)
"Clofazimine is an anti-leprosy drug that is normally only prescribed for a few years."1.56Fatal course of clofazimine-induced pulmonary crystal deposition in a patient with Melkersson-Rosenthal syndrome. ( Bittmann, I; Ganzert, C; Lücke, E; Schreiber, J; Wu, Q, 2020)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Wu, Q1
Ganzert, C1
Lücke, E1
Bittmann, I1
Schreiber, J1
Girdhar, A1
Venkatesan, K1
Chauhan, SL1
Malaviya, GN1
Girdhar, BK1

Other Studies

2 other studies available for clofazimine and Hemoptysis

ArticleYear
Fatal course of clofazimine-induced pulmonary crystal deposition in a patient with Melkersson-Rosenthal syndrome.
    International journal of clinical pharmacology and therapeutics, 2020, Volume: 58, Issue:9

    Topics: Biopsy; Clofazimine; Fatal Outcome; Hemoptysis; Humans; Male; Melkersson-Rosenthal Syndrome; Respira

2020
Red discoloration of the sputum by clofazimine simulating haemoptysis--a case report.
    Leprosy review, 1992, Volume: 63, Issue:1

    Topics: Adolescent; Clofazimine; Diagnostic Errors; Erythema Nodosum; Hemoptysis; Humans; Leprosy, Lepromato

1992