clofazimine has been researched along with Hematologic Diseases in 2 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Hematologic Diseases: Disorders of the blood and blood forming tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clofazimine (Lamprene) is an antimycobacterial drug that has antiinflammatory activity in a number of chronic autoimmune skin disorders." | 6.68 | Treatment of chronic graft-versus-host disease with clofazimine. ( Antin, JH; Bierer, BE; Lee, SJ; McGarigle, CJ; Wegner, SA, 1997) |
| "Clofazimine (Lamprene) is an antimycobacterial drug that has antiinflammatory activity in a number of chronic autoimmune skin disorders." | 2.68 | Treatment of chronic graft-versus-host disease with clofazimine. ( Antin, JH; Bierer, BE; Lee, SJ; McGarigle, CJ; Wegner, SA, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murray, JC | 1 |
| Lee, SJ | 1 |
| Wegner, SA | 1 |
| McGarigle, CJ | 1 |
| Bierer, BE | 1 |
| Antin, JH | 1 |
1 review available for clofazimine and Hematologic Diseases
| Article | Year |
|---|---|
Pyoderma gangrenosum with IgA gammopathy.
Topics: Arthritis; Clofazimine; Gastrointestinal Diseases; Hematologic Diseases; Humans; Hypergammaglobuline | 1983 |
1 trial available for clofazimine and Hematologic Diseases
| Article | Year |
|---|---|
Treatment of chronic graft-versus-host disease with clofazimine.
Topics: Adjuvants, Immunologic; Adult; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Transplantation; | 1997 |