clofazimine has been researched along with Hand Deformities, Acquired in 2 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Hand Deformities, Acquired: Deformities of the hand, or a part of the hand, acquired after birth as the result of injury or disease.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, P | 1 |
| Kar, HK | 1 |
| Misra, RS | 1 |
| Mukherjee, A | 1 |
| Kaur, H | 1 |
| Mukherjee, R | 1 |
| Rani, R | 1 |
| Ramu, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety Study of Immunomodulator (Mycobacterium w) as an Adjunct Therapy in Category-II Pulmonary Tuberculosis Along With Assessment of Immunological Parameters[NCT00265226] | Phase 3 | 1,020 participants (Actual) | Interventional | 2005-03-31 | Completed | ||
| Efficacy and Safety of Immunomodulator (Mycobacterium w.) as an Adjunct Therapy in Category I Pulmonary Tuberculosis and Along With Assessment of Immunological Parameters[NCT00341328] | Phase 3 | 300 participants (Actual) | Interventional | 2007-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for clofazimine and Hand Deformities, Acquired
| Article | Year |
|---|---|
Disabilities in multibacillary leprosy following multidrug therapy with and without immunotherapy with Mycobacterium w antileprosy vaccine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Vaccines; Clofazimine; Disabled Persons; Double-B | 1999 |
Disabilities in multibacillary leprosy following multidrug therapy with and without immunotherapy with Mycobacterium w antileprosy vaccine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Vaccines; Clofazimine; Disabled Persons; Double-B | 1999 |
Disabilities in multibacillary leprosy following multidrug therapy with and without immunotherapy with Mycobacterium w antileprosy vaccine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Vaccines; Clofazimine; Disabled Persons; Double-B | 1999 |
Disabilities in multibacillary leprosy following multidrug therapy with and without immunotherapy with Mycobacterium w antileprosy vaccine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Vaccines; Clofazimine; Disabled Persons; Double-B | 1999 |
Management of reactions in leprosy.
Topics: Adrenal Cortex Hormones; Clofazimine; Hand Deformities, Acquired; Humans; Leprosy; Neuritis; Skin Ul | 1973 |