clofazimine has been researched along with Genetic Predisposition in 2 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Velayati, AA | 1 |
| Farnia, P | 1 |
| Khalizadeh, S | 1 |
| Farahbod, AM | 1 |
| Hasanzadh, M | 1 |
| Sheikolslam, MF | 1 |
| Sekar, B | 1 |
| Arunagiri, K | 1 |
| Kumar, BN | 1 |
| Narayanan, S | 1 |
| Menaka, K | 1 |
| Oommen, PK | 1 |
2 other studies available for clofazimine and Genetic Predisposition
| Article | Year |
|---|---|
Interferon-gamma receptor-1 gene promoter polymorphisms and susceptibility to leprosy in children of a single family.
Topics: Child; Clofazimine; Family; Genetic Predisposition to Disease; Humans; Interferon gamma Receptor; Le | 2011 |
Detection of mutations in folp1, rpoB and gyrA genes of M. leprae by PCR- direct sequencing--a rapid tool for screening drug resistance in leprosy.
Topics: Animals; Bacterial Proteins; Biopsy; Clofazimine; Cross-Sectional Studies; Dapsone; Dihydropteroate | 2011 |