Page last updated: 2024-10-25

clofazimine and Eye Disorders

clofazimine has been researched along with Eye Disorders in 5 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ravanes, JM1
Cellona, RV1
Balagon, M1
Abalos, RM1
Walsh, GP1
Walsh, DS1
Moore, VJ1
Greer, KE1
Cooper, PH1
Forster, DJ1
Causey, DM1
Rao, NA1
Ffytche, TJ1
McDougall, AC1

Reviews

1 review available for clofazimine and Eye Disorders

ArticleYear
Sweet's syndrome (acute febrile neutrophilic dermatosis).
    Clinics in rheumatic diseases, 1982, Volume: 8, Issue:2

    Topics: Adult; Arthritis; Clofazimine; Diagnosis, Differential; Eye Diseases; Female; Fever; Humans; Indomet

1982

Trials

1 trial available for clofazimine and Eye Disorders

ArticleYear
Longitudinal ocular survey of 202 Filipino patients with multi-bacillary (MB) leprosy treated with 2 year WHO-multiple drug therapy.
    The Southeast Asian journal of tropical medicine and public health, 2011, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Clofazimine; Dapsone; Drug Ther

2011

Other Studies

3 other studies available for clofazimine and Eye Disorders

ArticleYear
A review of side-effects experienced by patients taking clofazimine.
    Leprosy review, 1983, Volume: 54, Issue:4

    Topics: Clofazimine; Digestive System; Eye Diseases; Humans; Leprosy; Pigmentation Disorders; Time Factors

1983
Bull's eye retinopathy and clofazimine.
    Annals of internal medicine, 1992, May-15, Volume: 116, Issue:10

    Topics: Adult; Clofazimine; Eye Diseases; Humans; Male; Pigment Epithelium of Eye

1992
Leprosy and the eye: a review.
    Journal of the Royal Society of Medicine, 1985, Volume: 78, Issue:5

    Topics: Bacterial Vaccines; Clofazimine; Dapsone; Drug Therapy, Combination; Eye Diseases; Humans; Leprosy;

1985