clofazimine has been researched along with Ehlers-Danlos Syndrome in 1 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Ehlers-Danlos Syndrome: A heterogeneous group of autosomally inherited COLLAGEN DISEASES caused by defects in the synthesis or structure of FIBRILLAR COLLAGEN. There are numerous subtypes: classical, hypermobility, vascular, and others. Common clinical features include hyperextensible skin and joints, skin fragility and reduced wound healing capability.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The term "granulomatous slack skin" (GSS) was introduced by Ackerman for a disease first described by Convit et al." | 2.39 | ["Granulomatous slack skin"--cutaneous elastolytic lymphoma]. ( Mielke, V; Simon, M; Staib, G; Sterry, W; Tacke, J; von den Driesch, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| von den Driesch, P | 1 |
| Mielke, V | 1 |
| Simon, M | 1 |
| Staib, G | 1 |
| Tacke, J | 1 |
| Sterry, W | 1 |
1 review available for clofazimine and Ehlers-Danlos Syndrome
| Article | Year |
|---|---|
["Granulomatous slack skin"--cutaneous elastolytic lymphoma].
Topics: Biopsy; Clofazimine; Combined Modality Therapy; Ehlers-Danlos Syndrome; Elastic Tissue; Etretinate; | 1994 |