clofazimine has been researched along with Duodenal Diseases in 3 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Duodenal Diseases: Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clofazimine, previously used in the treatment of leprosy, is now used for treatment of Mycobacterium avium complex infection in patients with acquired immune deficiency syndrome, dermatologic disorders, and graft-versus-host disease." | 3.71 | Clofazimine enteropathy in a pediatric bone marrow transplant recipient. ( Di Lorenzo, C; Goyal, RK; Parizhskaya, M; Youssef, NN, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Jin, B | 1 |
| Li, J | 1 |
| Zhao, S | 1 |
| Raftopoulos, SC | 1 |
| Fermoyle, S | 1 |
| Parizhskaya, M | 1 |
| Youssef, NN | 1 |
| Di Lorenzo, C | 1 |
| Goyal, RK | 1 |
3 other studies available for clofazimine and Duodenal Diseases
| Article | Year |
|---|---|
A rare case of enteral discoloration.
Topics: Adult; Antitubercular Agents; Clofazimine; Color; Duodenal Diseases; Endoscopy, Gastrointestinal; Fe | 2019 |
An unusual cause of small-intestine mucosal pigmentation.
Topics: Adult; Clofazimine; Duodenal Diseases; Endoscopy, Digestive System; Erythema Nodosum; Humans; Lepros | 2011 |
Clofazimine enteropathy in a pediatric bone marrow transplant recipient.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Bone Marrow Transplantation; Child; Clofazimine; Du | 2001 |