clofazimine has been researched along with Dermatitis Medicamentosa in 7 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Side-effects of leprosy treatment with dapsone are said to be uncommon, with drug allergy occurring in only one of every several hundred patients treated with dapsone." | 7.68 | Dapsone syndrome in Vanuatu: a high incidence during multidrug treatment (MDT) of leprosy. ( Ala, J; Hall, JJ; Reeve, PA, 1992) |
| "Side-effects of leprosy treatment with dapsone are said to be uncommon, with drug allergy occurring in only one of every several hundred patients treated with dapsone." | 3.68 | Dapsone syndrome in Vanuatu: a high incidence during multidrug treatment (MDT) of leprosy. ( Ala, J; Hall, JJ; Reeve, PA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krop, LC | 1 |
| Johnson, DP | 1 |
| Baxt, RD | 1 |
| Reeve, PA | 1 |
| Ala, J | 1 |
| Hall, JJ | 1 |
| Fitzpatrick, JE | 1 |
| Job, CK | 1 |
| Yoder, L | 1 |
| Jacobson, RR | 1 |
| Hastings, RC | 1 |
| Patki, AH | 1 |
| Jadhav, VH | 1 |
| Mehta, JM | 1 |
| Pavithran, K | 1 |
1 review available for clofazimine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
New histopathologic findings in drug eruptions.
Topics: Amiodarone; Antineoplastic Agents; Cephalosporins; Clofazimine; Drug Eruptions; Humans; Naproxen; Pi | 1992 |
6 other studies available for clofazimine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Cutaneous disease and drug reactions in HIV infection.
Topics: Clofazimine; Drug Eruptions; HIV Infections; Humans; Pigmentation Disorders; Skin Diseases | 1993 |
Lepromatous leprosy with drug reaction.
Topics: Clofazimine; Dapsone; Drug Eruptions; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy | 2000 |
Dapsone syndrome in Vanuatu: a high incidence during multidrug treatment (MDT) of leprosy.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Clofazimine; Dapsone; Drug Eruptions; Dru | 1992 |
Skin pigmentation from clofazimine therapy in leprosy patients: a reappraisal.
Topics: Aged; Aged, 80 and over; Clofazimine; Drug Eruptions; Female; Humans; Leprosy, Lepromatous; Male; Ne | 1990 |
A study of dermatological conditions in leprosy in-patients.
Topics: Clofazimine; Drug Eruptions; Female; Humans; Inpatients; Keratosis; Leprosy; Male; Pigmentation Diso | 1989 |
Exfoliative dermatitis after clofazimine.
Topics: Clofazimine; Dermatitis, Exfoliative; Drug Eruptions; Humans; Leprosy; Male; Middle Aged | 1985 |