Compounds > clofazimine
Page last updated: 2024-10-25

clofazimine and Delayed Hypersensitivity

clofazimine has been researched along with Delayed Hypersensitivity in 4 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhattacharya, SN1
Chattopadhaya, D1
Saha, K1
Naafs, B2
Bourée, P1
de Brette, A1
de Carsalade, GY1

Reviews

1 review available for clofazimine and Delayed Hypersensitivity

ArticleYear
Bangkok Workshop on Leprosy Research. Treatment of reactions and nerve damage.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1996, Volume: 64, Issue:4 Suppl

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Cyclosporine; Drug A

1996

Other Studies

3 other studies available for clofazimine and Delayed Hypersensitivity

ArticleYear
Tumor necrosis factor: status in reactions in leprosy before and after treatment.
    International journal of dermatology, 1993, Volume: 32, Issue:6

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Clofazimine; Eryt

1993
Viewpoint: leprosy after the year 2000.
    Tropical medicine & international health : TM & IH, 2000, Volume: 5, Issue:6

    Topics: Clofazimine; Drug Therapy, Combination; Global Health; Humans; Hypersensitivity, Delayed; Leprostati

2000
[Late reversal leprous reaction appearing 18 months after the termination of treatment].
    Presse medicale (Paris, France : 1983), 2001, Mar-03, Volume: 30, Issue:8

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Clofazimine; Coloring Age

2001