clofazimine has been researched along with Corneal Opacity in 1 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Corneal Opacity: Disorder occurring in the central or peripheral area of the cornea. The usual degree of transparency becomes relatively opaque.
| Excerpt | Relevance | Reference |
|---|---|---|
| " He received clofazimine (Lamprene) at a dosage of 100 mg twice daily." | 1.28 | Polychromatic corneal and conjunctival crystals secondary to clofazimine therapy in a leper. ( Font, RL; Matoba, A; Sobol, W, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Font, RL | 1 |
| Sobol, W | 1 |
| Matoba, A | 1 |
1 other study available for clofazimine and Corneal Opacity
| Article | Year |
|---|---|
Polychromatic corneal and conjunctival crystals secondary to clofazimine therapy in a leper.
Topics: Aged; Biopsy; Clofazimine; Conjunctiva; Conjunctival Diseases; Corneal Opacity; Crystallization; Hum | 1989 |