clofazimine has been researched along with Complications, Infectious Pregnancy in 4 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Excerpt | Relevance | Reference |
---|---|---|
"Clofazimine enterophathy is a serious complication of clofazimine when used at high doses for treatment of type 2 lepra or or erythema nodosum leprosum." | 7.75 | [Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy]. ( Gómez, Y; López, F; Pinto, R; Rodríguez, G, 2009) |
"Little is known of the perinatal consequences of the use of clofazimine (B663, Lamprene) to treat leprosy." | 7.66 | Clofazimine in pregnancy complicated by leprosy. ( Farb, H; Pedvis-Leftick, A; West, DP, 1982) |
"Clofazimine enterophathy is a serious complication of clofazimine when used at high doses for treatment of type 2 lepra or or erythema nodosum leprosum." | 3.75 | [Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy]. ( Gómez, Y; López, F; Pinto, R; Rodríguez, G, 2009) |
"Little is known of the perinatal consequences of the use of clofazimine (B663, Lamprene) to treat leprosy." | 3.66 | Clofazimine in pregnancy complicated by leprosy. ( Farb, H; Pedvis-Leftick, A; West, DP, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Rodríguez, G | 1 |
Pinto, R | 1 |
López, F | 1 |
Gómez, Y | 1 |
Farb, H | 1 |
West, DP | 1 |
Pedvis-Leftick, A | 1 |
Bhargava, P | 1 |
Kuldeep, CM | 1 |
Mathur, NK | 1 |
Holdiness, MR | 1 |
4 other studies available for clofazimine and Complications, Infectious Pregnancy
Article | Year |
---|---|
[Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy].
Topics: Abdominal Pain; Adult; Arthritis, Rheumatoid; Child; Child, Preschool; Clofazimine; Constipation; Di | 2009 |
Clofazimine in pregnancy complicated by leprosy.
Topics: Adult; Clofazimine; Female; Humans; Infant, Newborn; Leprosy; Pregnancy; Pregnancy Complications, In | 1982 |
Antileprosy drugs, pregnancy and fetal outcome.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combina | 1996 |
Clofazimine in pregnancy.
Topics: Clofazimine; Female; Fetal Death; Fetal Diseases; Humans; Leprosy; Pregnancy; Pregnancy Complication | 1989 |