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clofazimine and Complications, Infectious Pregnancy

clofazimine has been researched along with Complications, Infectious Pregnancy in 4 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Research Excerpts

ExcerptRelevanceReference
"Clofazimine enterophathy is a serious complication of clofazimine when used at high doses for treatment of type 2 lepra or or erythema nodosum leprosum."7.75[Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy]. ( Gómez, Y; López, F; Pinto, R; Rodríguez, G, 2009)
"Little is known of the perinatal consequences of the use of clofazimine (B663, Lamprene) to treat leprosy."7.66Clofazimine in pregnancy complicated by leprosy. ( Farb, H; Pedvis-Leftick, A; West, DP, 1982)
"Clofazimine enterophathy is a serious complication of clofazimine when used at high doses for treatment of type 2 lepra or or erythema nodosum leprosum."3.75[Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy]. ( Gómez, Y; López, F; Pinto, R; Rodríguez, G, 2009)
"Little is known of the perinatal consequences of the use of clofazimine (B663, Lamprene) to treat leprosy."3.66Clofazimine in pregnancy complicated by leprosy. ( Farb, H; Pedvis-Leftick, A; West, DP, 1982)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rodríguez, G1
Pinto, R1
López, F1
Gómez, Y1
Farb, H1
West, DP1
Pedvis-Leftick, A1
Bhargava, P1
Kuldeep, CM1
Mathur, NK1
Holdiness, MR1

Other Studies

4 other studies available for clofazimine and Complications, Infectious Pregnancy

ArticleYear
[Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy].
    Biomedica : revista del Instituto Nacional de Salud, 2009, Volume: 29, Issue:1

    Topics: Abdominal Pain; Adult; Arthritis, Rheumatoid; Child; Child, Preschool; Clofazimine; Constipation; Di

2009
Clofazimine in pregnancy complicated by leprosy.
    Obstetrics and gynecology, 1982, Volume: 59, Issue:1

    Topics: Adult; Clofazimine; Female; Humans; Infant, Newborn; Leprosy; Pregnancy; Pregnancy Complications, In

1982
Antileprosy drugs, pregnancy and fetal outcome.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1996, Volume: 64, Issue:4

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combina

1996
Clofazimine in pregnancy.
    Early human development, 1989, Volume: 18, Issue:4

    Topics: Clofazimine; Female; Fetal Death; Fetal Diseases; Humans; Leprosy; Pregnancy; Pregnancy Complication

1989