Page last updated: 2024-10-25

clofazimine and Co-infection

clofazimine has been researched along with Co-infection in 3 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Research Excerpts

ExcerptRelevanceReference
"Clofazimine was associated with improved culture conversion in the treatment of XDR-TB/HIV."5.40Clofazimine in the treatment of extensively drug-resistant tuberculosis with HIV coinfection in South Africa: a retrospective cohort study. ( Gopal, M; Master, I; Naidoo, K; Naidoo, R; O'Donnell, MR; Padayatchi, N; Werner, L, 2014)
"Clofazimine was associated with improved culture conversion in the treatment of XDR-TB/HIV."1.40Clofazimine in the treatment of extensively drug-resistant tuberculosis with HIV coinfection in South Africa: a retrospective cohort study. ( Gopal, M; Master, I; Naidoo, K; Naidoo, R; O'Donnell, MR; Padayatchi, N; Werner, L, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Padayatchi, N1
Gopal, M1
Naidoo, R1
Werner, L1
Naidoo, K1
Master, I1
O'Donnell, MR1
Markowitz, N1
Agarwal, U1
Baxa, D1
Ganesan, V1
Mandal, J1

Other Studies

3 other studies available for clofazimine and Co-infection

ArticleYear
Clofazimine in the treatment of extensively drug-resistant tuberculosis with HIV coinfection in South Africa: a retrospective cohort study.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:11

    Topics: Adult; Antitubercular Agents; Clofazimine; Cohort Studies; Coinfection; Extensively Drug-Resistant T

2014
Hypothesis: Can clofazimine prevent IRIS in HIV/TB co-infected individuals?
    The Indian journal of tuberculosis, 2014, Volume: 61, Issue:4

    Topics: Anti-Inflammatory Agents; Anti-Retroviral Agents; Antitubercular Agents; Clofazimine; Coinfection; H

2014
Primary oral tuberculosis in a patient with lepromatous leprosy: Diagnostic dilemma.
    International journal of mycobacteriology, 2016, Volume: 5, Issue:1

    Topics: Anti-Inflammatory Agents; Clofazimine; Coinfection; Female; Humans; Leprostatic Agents; Leprosy, Lep

2016