clofazimine has been researched along with Cheilitis Granulomatosa in 23 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A pilot study with the anti-leprosy agent clofazimine was conducted on seven patients with cheilitis granulomatosa or complete Melkersson-Rosenthal syndrome." | 7.67 | [Cheilitis granulomatosa (Melkersson-Rosenthal syndrome): treatment with clofazimine]. ( Fritsch, P; Neuhofer, J, 1984) |
| "Clofazimine is an anti-leprosy drug that is normally only prescribed for a few years." | 1.56 | Fatal course of clofazimine-induced pulmonary crystal deposition in a patient with Melkersson-Rosenthal syndrome. ( Bittmann, I; Ganzert, C; Lücke, E; Schreiber, J; Wu, Q, 2020) |
| "Clofazimine seems to be an effective treatment, although long-term application is necessary with frequent aggravation in the beginning." | 1.34 | Cheilitis granulomatosa and Melkersson-Rosenthal syndrome: evaluation of gastrointestinal involvement and therapeutic regimens in a series of 14 patients. ( Ratzinger, G; Sepp, N; Tilg, H; Vogetseder, W, 2007) |
| "The management of cheilitis granulomatosa remains a challenge." | 1.31 | Cheilitis granulomatosa: overview of 13 patients with long-term follow-up--results of management. ( Schulten, EA; Starink, TM; van de Scheur, MR; van der Meij, EH; van der Waal, I; van der Waal, RI, 2002) |
| " Recurrences have been suppressed with a reduced maintenance dosage of this agent." | 1.29 | Granulomatous glossitis as an unusual manifestation of Melkersson-Rosenthal syndrome. ( Boateng, BI; Hornstein, OP; Kiesewetter, FF; Mahler, VB, 1995) |
| "Treatment with clofazimine (100 mg 4 times weekly for 3-11 months) was associated with complete remission in 5/10 patients and clinical improvement in 3/10 patients with moderate constant swelling." | 1.28 | Melkersson-Rosenthal syndrome: clinical, pathologic, and therapeutic considerations. ( Steinberg, S; Sussman, GL; Yang, WH, 1992) |
| "Treatment with clofazimine dramatically improved swelling of the lips." | 1.28 | [Melkersson-Rosenthal syndrome. A case treated with clofazimine]. ( Cusano, F; Errico, A; Errico, G; Lamparelli, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, Q | 1 |
| Ganzert, C | 1 |
| Lücke, E | 1 |
| Bittmann, I | 1 |
| Schreiber, J | 1 |
| Sachdeva, S | 1 |
| Raina, A | 1 |
| Sardana, K | 1 |
| Malhotra, P | 1 |
| López-Urbano, MJ | 1 |
| Villar, MA | 1 |
| Ruiz Villaverde, R | 2 |
| Avila, IR | 1 |
| Vijayalakshmi, AM | 1 |
| Jayavardhana, A | 1 |
| Sánchez Cano, D | 1 |
| Banks, T | 1 |
| Gada, S | 1 |
| Madke, BS | 1 |
| Ghia, D | 1 |
| Gadkari, R | 1 |
| Nayak, C | 1 |
| Nagel, F | 1 |
| Foelster-Holst, R | 1 |
| Ratzinger, G | 1 |
| Sepp, N | 1 |
| Vogetseder, W | 1 |
| Tilg, H | 1 |
| Bygum, A | 1 |
| Toft-Petersen, M | 1 |
| Neuhofer, J | 1 |
| Fritsch, P | 1 |
| Mahler, VB | 1 |
| Hornstein, OP | 1 |
| Boateng, BI | 1 |
| Kiesewetter, FF | 1 |
| Mahler, V | 1 |
| Kiesewetter, F | 1 |
| Heinz, C | 1 |
| Weinmann, I | 1 |
| Heiligenhaus, A | 1 |
| Altmeyer, P | 1 |
| Steuhl, KP | 1 |
| Ridder, GJ | 1 |
| Fradis, M | 1 |
| Löhle, E | 1 |
| van der Waal, RI | 1 |
| Schulten, EA | 1 |
| van der Meij, EH | 1 |
| van de Scheur, MR | 1 |
| Starink, TM | 1 |
| van der Waal, I | 1 |
| Sussman, GL | 1 |
| Yang, WH | 1 |
| Steinberg, S | 1 |
| Tausch, I | 1 |
| Sönnichsen, N | 1 |
| Cusano, F | 1 |
| Lamparelli, A | 1 |
| Errico, A | 1 |
| Errico, G | 1 |
| Friedrich, W | 1 |
| Timmermann, J | 1 |
| Gall, Y | 1 |
| Bureau, B | 1 |
| Stalder, JF | 1 |
| Litoux, P | 1 |
| Bosco, G | 1 |
| Leoni, A | 1 |
| Podmore, P | 1 |
| Burrows, D | 1 |
3 reviews available for clofazimine and Cheilitis Granulomatosa
| Article | Year |
|---|---|
A comprehensive review of current treatments for granulomatous cheilitis.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Clofazimine; Humans; Immun | 2012 |
[Cheilitis granulomatosa Melkersson-Rosenthal syndrome].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Humans; Melkersson-Ro | 2006 |
Cheilitis granulomatosa Miescher: treatment with clofazimine and review of the literature.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Coloring Agents; Female; Humans; M | 2001 |
20 other studies available for clofazimine and Cheilitis Granulomatosa
| Article | Year |
|---|---|
Fatal course of clofazimine-induced pulmonary crystal deposition in a patient with Melkersson-Rosenthal syndrome.
Topics: Biopsy; Clofazimine; Fatal Outcome; Hemoptysis; Humans; Male; Melkersson-Rosenthal Syndrome; Respira | 2020 |
A case of orofacial granulomatosis evolving into Melkersson Rosenthal syndrome in a child treated with a steroid free regimen of Clofazimine and Minocycline.
Topics: Adolescent; Clofazimine; Female; Granulomatosis, Orofacial; Humans; Melkersson-Rosenthal Syndrome; M | 2021 |
Granulomatous cheilitis: a condition that merits inclusion in the differential diagnosis of angioedema.
Topics: Adult; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Diagnosis, Differential; Hu | 2009 |
Persistent swelling of lip.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Clofazimine; Humans; Lip; Male; Melkersson-Rosenthal | 2009 |
Successful treatment of granulomatous cheilitis with adalimumab.
Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Biopsy; Clofazimine; Female | 2012 |
Cheilitis granulomatosa (Miescher granulomatous macrocheilitis) with trisomy 21.
Topics: Adult; Anti-Inflammatory Agents; Clofazimine; Down Syndrome; Humans; Male; Melkersson-Rosenthal Synd | 2012 |
Cheilitis granulomatosa and Melkersson-Rosenthal syndrome: evaluation of gastrointestinal involvement and therapeutic regimens in a series of 14 patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Capsule Endoscopy; Clo | 2007 |
[Melkersson-Rosenthal syndrome treated with clofazimine].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Female; Humans; Melkersson-Rosenthal Sy | 2008 |
[Cheilitis granulomatosa (Melkersson-Rosenthal syndrome): treatment with clofazimine].
Topics: Adolescent; Adult; Clofazimine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; | 1984 |
Granulomatous glossitis as an unusual manifestation of Melkersson-Rosenthal syndrome.
Topics: Clofazimine; Diagnosis, Differential; Edema; Glossitis; Granuloma; Humans; Lip Diseases; Male; Melke | 1995 |
[Glossitis granulomatosa symptom of oligosymptomatic Melkersson-Rosenthal syndrome].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Clofazimine; Diagnosis, Differential; Glossitis; Hu | 1996 |
Bilateral conjunctival lesions in Melkersson-Rosenthal syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Conjunctival Diseases; Humans; Male; Melkersso | 2001 |
Cheilitis granulomatosa: overview of 13 patients with long-term follow-up--results of management.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle | 2002 |
Melkersson-Rosenthal syndrome: clinical, pathologic, and therapeutic considerations.
Topics: Adolescent; Adult; Biopsy; Child; Clofazimine; Female; Humans; Lip; Male; Melkersson-Rosenthal Syndr | 1992 |
[Experiences with clofazimine therapy of Melkersson-Rosenthal syndrome].
Topics: Adult; Biopsy; Clofazimine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; | 1992 |
[Melkersson-Rosenthal syndrome. A case treated with clofazimine].
Topics: Biopsy; Clofazimine; Drug Evaluation; Female; Humans; Lip; Melkersson-Rosenthal Syndrome; Middle Age | 1991 |
[Miescher's granulomatous cheilitis. Diagnostic and therapeutic aspects].
Topics: Adrenal Cortex Hormones; Adult; Clofazimine; Drug Administration Schedule; Female; Humans; Lip; Melk | 1990 |
[Miescher's granulomatous macrocheilitis. Treatment with clofazimine].
Topics: Cheilitis; Child; Clofazimine; Female; Humans; Melkersson-Rosenthal Syndrome | 1989 |
[A case of Melkersson-Rosenthal syndrome].
Topics: Clofazimine; Humans; Male; Melkersson-Rosenthal Syndrome; Middle Aged | 1987 |
Clofazimine--an effective treatment for Melkersson-Rosenthal syndrome or Miescher's cheilitis.
Topics: Adolescent; Adult; Cheilitis; Clofazimine; Female; Humans; Male; Melkersson-Rosenthal Syndrome; Skin | 1986 |