clofazimine has been researched along with Cell Transformation, Neoplastic in 1 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scagliola, A | 1 |
| Miluzio, A | 1 |
| Ventura, G | 1 |
| Oliveto, S | 1 |
| Cordiglieri, C | 1 |
| Manfrini, N | 1 |
| Cirino, D | 1 |
| Ricciardi, S | 1 |
| Valenti, L | 1 |
| Baselli, G | 1 |
| D'Ambrosio, R | 1 |
| Maggioni, M | 1 |
| Brina, D | 1 |
| Bresciani, A | 1 |
| Biffo, S | 1 |
1 other study available for clofazimine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Protein-beta; Cell Line; Cell Transformat | 2021 |