Page last updated: 2024-10-25

clofazimine and Cardiac Diseases

clofazimine has been researched along with Cardiac Diseases in 1 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Ng, PCI1
Chan, JYW1
Leung, RKK1
Li, J1
Ren, Z1
Chan, AWH1
Xu, Y1
Lee, SS1
Wang, R1
Ji, X1
Zheng, J1
Chan, DPC1
Yew, WW1
Lee, SMY1

Other Studies

1 other study available for clofazimine and Cardiac Diseases

ArticleYear
Role of oxidative stress in clofazimine-induced cardiac dysfunction in a zebrafish model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 132

    Topics: Acetylcysteine; Animals; Antitubercular Agents; Clofazimine; Disease Models, Animal; Gene Expression

2020