Page last updated: 2024-10-25

clofazimine and Carcinoma, Small Cell

clofazimine has been researched along with Carcinoma, Small Cell in 2 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Van Rensburg, CE2
Anderson, R1
Myer, MS1
Jooné, GK1
O'Sullivan, JF1
Durandt, C1

Other Studies

2 other studies available for clofazimine and Carcinoma, Small Cell

ArticleYear
The riminophenazine agents clofazimine and B669 reverse acquired multidrug resistance in a human lung cancer cell line.
    Cancer letters, 1994, Sep-30, Volume: 85, Issue:1

    Topics: Anti-Infective Agents; Antineoplastic Agents; Carbon Radioisotopes; Carcinoma, Small Cell; Cell Divi

1994
Effects of tetramethylpiperidine (TMP)-substituted phenazines on membrane stability and P-glycoprotein function.
    International journal of oncology, 2001, Volume: 19, Issue:3

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzothiazoles; Carcinoma, Small Cell; Cell

2001