Page last updated: 2024-10-25

clofazimine and Breast Neoplasms

clofazimine has been researched along with Breast Neoplasms in 3 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"Among the 48 human ABC proteins, the breast cancer resistance protein (BCRP/ABCG2) has been described as a pivotal player in cancer resistance."2.82Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. ( Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF, 2022)
"We describe a case of Sweet's syndrome in association with generalized granuloma annulare (GA) which presented 3 years after a diagnosis of breast carcinoma."1.31Sweet's syndrome in association with generalized granuloma annulare in a patient with previous breast carcinoma. ( Antony, F; Holden, CA, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Zattoni, IF1
Delabio, LC1
Dutra, JP1
Kita, DH1
Scheiffer, G1
Hembecker, M1
Pereira, GDS1
Moure, VR1
Valdameri, G1
Bailly, N1
Thomas, M1
Klumperman, B1
Antony, F1
Holden, CA1

Reviews

1 review available for clofazimine and Breast Neoplasms

ArticleYear
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Dr

2022

Other Studies

2 other studies available for clofazimine and Breast Neoplasms

ArticleYear
Poly(N-vinylpyrrolidone)-block-poly(vinyl acetate) as a drug delivery vehicle for hydrophobic drugs.
    Biomacromolecules, 2012, Dec-10, Volume: 13, Issue:12

    Topics: Biocompatible Materials; Breast Neoplasms; Cell Line, Tumor; Clofazimine; Drug Carriers; Female; Hum

2012
Sweet's syndrome in association with generalized granuloma annulare in a patient with previous breast carcinoma.
    Clinical and experimental dermatology, 2001, Volume: 26, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Clofazimine; Estrogen Antagonists; Female

2001