clofazimine has been researched along with Besnier-Boeck Disease in 6 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sarcoidosis is a chronic systemic granulomatous disease that occasionally affects the larynx." | 5.31 | Laryngeal sarcoidosis: treatment with the antileprosy drug clofazimine. ( Fradis, M; Golz, A; Löhle, E; Ridder, GJ; Strohhäcker, H, 2000) |
| " Under clofazimine (Lampren), at an initial dosage of 3 x 100 mg daily by mouth, gradually reduced over 4 months, the cutaneous lesions healed completely and lastingly." | 1.31 | [Disseminated small-node cutaneous sarcoidosis]. ( Djawari, D; Schwarzenbach, R, 2000) |
| "Sarcoidosis is a chronic systemic granulomatous disease that occasionally affects the larynx." | 1.31 | Laryngeal sarcoidosis: treatment with the antileprosy drug clofazimine. ( Fradis, M; Golz, A; Löhle, E; Ridder, GJ; Strohhäcker, H, 2000) |
| " Recurrences have been suppressed with a reduced maintenance dosage of this agent." | 1.29 | Granulomatous glossitis as an unusual manifestation of Melkersson-Rosenthal syndrome. ( Boateng, BI; Hornstein, OP; Kiesewetter, FF; Mahler, VB, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aftab, H | 1 |
| Nielsen, SD | 1 |
| Nielsen, SL | 1 |
| Due, E | 1 |
| Bygbjerg, IC | 1 |
| Thybo, S | 1 |
| Aram, H | 1 |
| Mahler, VB | 1 |
| Hornstein, OP | 1 |
| Boateng, BI | 1 |
| Kiesewetter, FF | 1 |
| Schwarzenbach, R | 1 |
| Djawari, D | 1 |
| Ridder, GJ | 1 |
| Strohhäcker, H | 1 |
| Löhle, E | 1 |
| Golz, A | 1 |
| Fradis, M | 1 |
| Burdick, AE | 1 |
| Hendi, A | 1 |
| Elgart, GW | 1 |
| Barquin, L | 1 |
| Scollard, DM | 1 |
1 review available for clofazimine and Besnier-Boeck Disease
| Article | Year |
|---|---|
Acquired ichthyosis and related conditions.
Topics: Aged; Cimetidine; Clofazimine; Female; Hodgkin Disease; Humans; Ichthyosis; Lymphoma; Male; Neoplasm | 1984 |
5 other studies available for clofazimine and Besnier-Boeck Disease
| Article | Year |
|---|---|
A case of leprosy mistaken for cutaneous sarcoidosis.
Topics: Adult; Clofazimine; Dapsone; Diagnostic Errors; Drug Therapy, Combination; Female; Humans; Leprostat | 2012 |
Granulomatous glossitis as an unusual manifestation of Melkersson-Rosenthal syndrome.
Topics: Clofazimine; Diagnosis, Differential; Edema; Glossitis; Granuloma; Humans; Lip Diseases; Male; Melke | 1995 |
[Disseminated small-node cutaneous sarcoidosis].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Clofazimine; Female; Humans; Progn | 2000 |
Laryngeal sarcoidosis: treatment with the antileprosy drug clofazimine.
Topics: Adult; Airway Obstruction; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biopsy | 2000 |
Hansen's disease in a patient with a history of sarcoidosis.
Topics: Anti-Inflammatory Agents; Biopsy; Clofazimine; Dapsone; Dermatologic Agents; Electromyography; Femal | 2000 |