clofazimine has been researched along with Autoimmune Diseases in 2 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Autoimmune Diseases: Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Its use in other autoimmune diseases has to be considered." | 1.26 | Clofazimine in dermatology. ( Mackey, JP, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mackey, JP | 1 |
| Pavithran, K | 1 |
2 other studies available for clofazimine and Autoimmune Diseases
| Article | Year |
|---|---|
Clofazimine in dermatology.
Topics: Autoimmune Diseases; Clofazimine; Humans; Ireland; Lupus Erythematosus, Discoid; Skin Diseases | 1976 |
Vitiligo following type II lepra reaction.
Topics: Autoimmune Diseases; Clofazimine; Dapsone; Drug Therapy, Combination; Follow-Up Studies; Humans; Lep | 1989 |