clofazimine has been researched along with Anemia, Hemolytic in 3 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Multidrug therapy for leprosy is currently done with dapsone, clofazimine and rifampicin." | 7.78 | Hemolytic anemia in patients receiving daily dapsone for the treatment of leprosy. ( Deps, P; Guerra, P; Nasser, S; Simon, M, 2012) |
| "Multidrug therapy for leprosy is currently done with dapsone, clofazimine and rifampicin." | 3.78 | Hemolytic anemia in patients receiving daily dapsone for the treatment of leprosy. ( Deps, P; Guerra, P; Nasser, S; Simon, M, 2012) |
| "Multidrug therapy (WHO/MDT) in multibacillary leprosy consists of treatment with rifampicin, dapsone and clofazimine." | 3.75 | Agranulocytosis induced by multidrug therapy in leprosy treatment: a case report. ( Guedes Filho, G; Guedes, WR; Oliveira, BB; Oliveira, CA; Oliveira, DA; Silva, IM, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silva, IM | 1 |
| Oliveira, CA | 1 |
| Guedes, WR | 1 |
| Oliveira, BB | 1 |
| Oliveira, DA | 1 |
| Guedes Filho, G | 1 |
| Deps, P | 1 |
| Guerra, P | 1 |
| Nasser, S | 1 |
| Simon, M | 1 |
| Leiker, DL | 1 |
1 review available for clofazimine and Anemia, Hemolytic
| Article | Year |
|---|---|
Chemotherapy in Leprosy.
Topics: Acetamides; Anemia, Hemolytic; Aniline Compounds; Animals; Clofazimine; Dapsone; Disease Models, Ani | 1975 |
2 other studies available for clofazimine and Anemia, Hemolytic
| Article | Year |
|---|---|
Agranulocytosis induced by multidrug therapy in leprosy treatment: a case report.
Topics: Adult; Agranulocytosis; Anemia, Hemolytic; Clofazimine; Dapsone; Drug Therapy, Combination; Female; | 2009 |
Hemolytic anemia in patients receiving daily dapsone for the treatment of leprosy.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Brazil; Clofazimine; Dapsone; Drug Therapy, Combination; | 2012 |