clofazimine has been researched along with Anasarca in 8 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The patient began treatment with clofazimine, rifampicin, and dapsone, but 15 days afterwards he complained of acral edema with godet sign." | 3.73 | Remitting seronegative symmetrical synovitis with pitting edema in leprosy. ( Helling, CA; Locursio, A; Manzur, ME; Sormani de Fonseca, ML, 2006) |
| " Prednisolone in standard dosage schedule as recommended by WHO is now being widely used in control programmes." | 1.32 | Reactions and their management. ( Ganapati, R; Pai, VV, 2004) |
| " Recurrences have been suppressed with a reduced maintenance dosage of this agent." | 1.29 | Granulomatous glossitis as an unusual manifestation of Melkersson-Rosenthal syndrome. ( Boateng, BI; Hornstein, OP; Kiesewetter, FF; Mahler, VB, 1995) |
| " ENL was also more frequent in regimens C and D and was not prevented by CLO in the dosage used." | 1.27 | Prospective study on the relationship between intensive bactericidal therapy and leprosy reactions. ( Coussens, L; Groenen, G; Janssens, L; Kayembe, T; Nollet, E; Pattyn, SR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hafiz, A | 1 |
| Mufeed, A | 1 |
| Kandasamy, G | 1 |
| Krishnapillai, R | 1 |
| Ganapati, R | 1 |
| Pai, VV | 1 |
| Helling, CA | 1 |
| Locursio, A | 1 |
| Manzur, ME | 1 |
| Sormani de Fonseca, ML | 1 |
| Mahler, VB | 1 |
| Hornstein, OP | 1 |
| Boateng, BI | 1 |
| Kiesewetter, FF | 1 |
| Tyagi, PY | 1 |
| Oommen, T | 1 |
| Venkateswarlu, B | 1 |
| Venkataramana, D | 1 |
| Rao, AV | 1 |
| Prabhakar, MC | 1 |
| Reddy, BM | 1 |
| Helander, I | 1 |
| Aho, HJ | 1 |
| Groenen, G | 1 |
| Janssens, L | 1 |
| Kayembe, T | 1 |
| Nollet, E | 1 |
| Coussens, L | 1 |
| Pattyn, SR | 1 |
8 other studies available for clofazimine and Anasarca
| Article | Year |
|---|---|
Uncommon inflammatory swelling of the lips: orofacial granulomatosis.
Topics: Anti-Inflammatory Agents; Child; Clofazimine; Edema; Female; Granuloma; Granulomatosis, Orofacial; H | 2016 |
Reactions and their management.
Topics: Arthritis; Cicatrix; Clofazimine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Ad | 2004 |
Remitting seronegative symmetrical synovitis with pitting edema in leprosy.
Topics: Aged; Clofazimine; Dapsone; Drug Therapy, Combination; Edema; Foot; Humans; Leprostatic Agents; Lepr | 2006 |
Granulomatous glossitis as an unusual manifestation of Melkersson-Rosenthal syndrome.
Topics: Clofazimine; Diagnosis, Differential; Edema; Glossitis; Granuloma; Humans; Lip Diseases; Male; Melke | 1995 |
Pedal edema following clofazimine therapy; a case report.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Edema; Foot Diseases; Humans; Leprosy, Borderline; | 1993 |
Role of rifampin and clofazimine ointments in the treatment of leprosy.
Topics: Clofazimine; Dermatitis; Drug Combinations; Edema; Erythema; Humans; Leprosy, Tuberculoid; Ointments | 1992 |
Solid facial edema as a complication of acne vulgaris: treatment with isotretinoin and clofazimine.
Topics: Acne Vulgaris; Adolescent; Adult; Clofazimine; Dermatologic Agents; Edema; Face; Female; Humans; Iso | 1987 |
Prospective study on the relationship between intensive bactericidal therapy and leprosy reactions.
Topics: Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Edema; Erythema Nodosum; Ethionamide; | 1986 |