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clofazimine and Anasarca

clofazimine has been researched along with Anasarca in 8 studies

Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.

Research Excerpts

ExcerptRelevanceReference
" The patient began treatment with clofazimine, rifampicin, and dapsone, but 15 days afterwards he complained of acral edema with godet sign."3.73Remitting seronegative symmetrical synovitis with pitting edema in leprosy. ( Helling, CA; Locursio, A; Manzur, ME; Sormani de Fonseca, ML, 2006)
" Prednisolone in standard dosage schedule as recommended by WHO is now being widely used in control programmes."1.32Reactions and their management. ( Ganapati, R; Pai, VV, 2004)
" Recurrences have been suppressed with a reduced maintenance dosage of this agent."1.29Granulomatous glossitis as an unusual manifestation of Melkersson-Rosenthal syndrome. ( Boateng, BI; Hornstein, OP; Kiesewetter, FF; Mahler, VB, 1995)
" ENL was also more frequent in regimens C and D and was not prevented by CLO in the dosage used."1.27Prospective study on the relationship between intensive bactericidal therapy and leprosy reactions. ( Coussens, L; Groenen, G; Janssens, L; Kayembe, T; Nollet, E; Pattyn, SR, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hafiz, A1
Mufeed, A1
Kandasamy, G1
Krishnapillai, R1
Ganapati, R1
Pai, VV1
Helling, CA1
Locursio, A1
Manzur, ME1
Sormani de Fonseca, ML1
Mahler, VB1
Hornstein, OP1
Boateng, BI1
Kiesewetter, FF1
Tyagi, PY1
Oommen, T1
Venkateswarlu, B1
Venkataramana, D1
Rao, AV1
Prabhakar, MC1
Reddy, BM1
Helander, I1
Aho, HJ1
Groenen, G1
Janssens, L1
Kayembe, T1
Nollet, E1
Coussens, L1
Pattyn, SR1

Other Studies

8 other studies available for clofazimine and Anasarca

ArticleYear
Uncommon inflammatory swelling of the lips: orofacial granulomatosis.
    BMJ case reports, 2016, Jan-12, Volume: 2016

    Topics: Anti-Inflammatory Agents; Child; Clofazimine; Edema; Female; Granuloma; Granulomatosis, Orofacial; H

2016
Reactions and their management.
    Journal of the Indian Medical Association, 2004, Volume: 102, Issue:12

    Topics: Arthritis; Cicatrix; Clofazimine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Ad

2004
Remitting seronegative symmetrical synovitis with pitting edema in leprosy.
    Clinical rheumatology, 2006, Volume: 25, Issue:1

    Topics: Aged; Clofazimine; Dapsone; Drug Therapy, Combination; Edema; Foot; Humans; Leprostatic Agents; Lepr

2006
Granulomatous glossitis as an unusual manifestation of Melkersson-Rosenthal syndrome.
    Cutis, 1995, Volume: 55, Issue:4

    Topics: Clofazimine; Diagnosis, Differential; Edema; Glossitis; Granuloma; Humans; Lip Diseases; Male; Melke

1995
Pedal edema following clofazimine therapy; a case report.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1993, Volume: 61, Issue:4

    Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Edema; Foot Diseases; Humans; Leprosy, Borderline;

1993
Role of rifampin and clofazimine ointments in the treatment of leprosy.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1992, Volume: 60, Issue:2

    Topics: Clofazimine; Dermatitis; Drug Combinations; Edema; Erythema; Humans; Leprosy, Tuberculoid; Ointments

1992
Solid facial edema as a complication of acne vulgaris: treatment with isotretinoin and clofazimine.
    Acta dermato-venereologica, 1987, Volume: 67, Issue:6

    Topics: Acne Vulgaris; Adolescent; Adult; Clofazimine; Dermatologic Agents; Edema; Face; Female; Humans; Iso

1987
Prospective study on the relationship between intensive bactericidal therapy and leprosy reactions.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1986, Volume: 54, Issue:2

    Topics: Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Edema; Erythema Nodosum; Ethionamide;

1986