clofazimine has been researched along with Abdominal Pain in 5 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clofazimine enterophathy is a serious complication of clofazimine when used at high doses for treatment of type 2 lepra or or erythema nodosum leprosum." | 7.75 | [Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy]. ( Gómez, Y; López, F; Pinto, R; Rodríguez, G, 2009) |
| "Clofazimine-induced crystal-storing histiocytosis is a rare but well-recognized condition in the literature." | 7.70 | Clofazimine-induced crystal-storing histiocytosis producing chronic abdominal pain in a leprosy patient. ( Akaraviputh, T; Chanchairujira, T; Hargrove, NS; Kachintorn, U; Manatsathit, S; Siritanaratkul, N; Sukpanichnant, S; Thakerngpol, K, 2000) |
| "We describe a 41 yr old leprosy patient treated for 10 yrs with clofazimine who underwent laparotomy for severe abdominal pain." | 7.68 | Severe abdominal pain in low dosage clofazimine. ( Chong, PY; Ti, TK, 1993) |
| "Clofazimine enterophathy is a serious complication of clofazimine when used at high doses for treatment of type 2 lepra or or erythema nodosum leprosum." | 3.75 | [Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy]. ( Gómez, Y; López, F; Pinto, R; Rodríguez, G, 2009) |
| "Clofazimine-induced crystal-storing histiocytosis is a rare but well-recognized condition in the literature." | 3.70 | Clofazimine-induced crystal-storing histiocytosis producing chronic abdominal pain in a leprosy patient. ( Akaraviputh, T; Chanchairujira, T; Hargrove, NS; Kachintorn, U; Manatsathit, S; Siritanaratkul, N; Sukpanichnant, S; Thakerngpol, K, 2000) |
| "We describe a 41 yr old leprosy patient treated for 10 yrs with clofazimine who underwent laparotomy for severe abdominal pain." | 3.68 | Severe abdominal pain in low dosage clofazimine. ( Chong, PY; Ti, TK, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodríguez, G | 1 |
| Pinto, R | 1 |
| López, F | 1 |
| Gómez, Y | 1 |
| Pais, AV | 1 |
| Pereira, S | 1 |
| Garg, I | 1 |
| Stephen, J | 1 |
| Antony, M | 1 |
| Inchara, YK | 1 |
| Chong, PY | 1 |
| Ti, TK | 1 |
| Soriano, V | 1 |
| Moreno, V | 1 |
| Alba, A | 1 |
| Laguna, F | 1 |
| González-Lahoz, J | 1 |
| Sukpanichnant, S | 1 |
| Hargrove, NS | 1 |
| Kachintorn, U | 1 |
| Manatsathit, S | 1 |
| Chanchairujira, T | 1 |
| Siritanaratkul, N | 1 |
| Akaraviputh, T | 1 |
| Thakerngpol, K | 1 |
1 review available for clofazimine and Abdominal Pain
| Article | Year |
|---|---|
Intra-abdominal, crystal-storing histiocytosis due to clofazimine in a patient with lepromatous leprosy and concurrent carcinoma of the colon.
Topics: Abdominal Pain; Adenocarcinoma; Adult; Clofazimine; Colonic Neoplasms; Crystallization; Female; Hist | 2004 |
4 other studies available for clofazimine and Abdominal Pain
| Article | Year |
|---|---|
[Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy].
Topics: Abdominal Pain; Adult; Arthritis, Rheumatoid; Child; Child, Preschool; Clofazimine; Constipation; Di | 2009 |
Severe abdominal pain in low dosage clofazimine.
Topics: Abdominal Pain; Adult; Clofazimine; Humans; Leprosy; Lymph Nodes; Male | 1993 |
Kussmaul respiration and abdominal pain secondary to metabolic acidosis in AIDS patients with disseminated Mycobacterium avium complex infection receiving clofazimine.
Topics: Abdominal Pain; Acidosis; Acquired Immunodeficiency Syndrome; Clofazimine; Humans; Male; Mycobacteri | 1993 |
Clofazimine-induced crystal-storing histiocytosis producing chronic abdominal pain in a leprosy patient.
Topics: Abdominal Pain; Adult; Biopsy; Chronic Disease; Clofazimine; Crystallization; Cytoplasm; Diagnosis, | 2000 |