clofazimine has been researched along with 2019 Novel Coronavirus Disease in 4 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Shi, Y | 1 |
| Guo, Z | 1 |
| Zhao, X | 1 |
| Wu, J | 1 |
| Cao, S | 1 |
| Liu, Y | 1 |
| Li, Y | 2 |
| Huang, W | 1 |
| Wang, Y | 1 |
| Liu, Q | 1 |
| Song, D | 1 |
| Koval, A | 1 |
| Xu, J | 1 |
| Williams, N | 1 |
| Schmolke, M | 1 |
| Krause, KH | 1 |
| Katanaev, VL | 1 |
| Lee, JH | 1 |
| An, HK | 1 |
| Sohn, MG | 1 |
| Kivela, P | 1 |
| Oh, S | 1 |
| Cerqueira, SRPS | 1 |
| Deps, PD | 1 |
| Cunha, DV | 1 |
| Bezerra, NVF | 1 |
| Barroso, DH | 1 |
| Pinheiro, ABS | 1 |
| Pillegi, GS | 1 |
| Repsold, TAR | 1 |
| Kurizky, PS | 1 |
| Collin, SM | 1 |
| Gomes, CM | 1 |
4 other studies available for clofazimine and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Clofazimine derivatives as potent broad-spectrum antiviral agents with dual-target mechanism.
Topics: Antiviral Agents; Clofazimine; COVID-19; Humans; SARS-CoV-2 | 2022 |
Wnt-Independent SARS-CoV-2 Infection in Pulmonary Epithelial Cells.
Topics: beta Catenin; Clofazimine; COVID-19; Epithelial Cells; Humans; Lung; SARS-CoV-2 | 2023 |
4,4'-Diaminodiphenyl Sulfone (DDS) as an Inflammasome Competitor.
Topics: Alzheimer Disease; Clofazimine; Cognitive Dysfunction; Coronavirus Infections; COVID-19; Dapsone; Hu | 2020 |
The influence of leprosy-related clinical and epidemiological variables in the occurrence and severity of COVID-19: A prospective real-world cohort study.
Topics: Adrenal Cortex Hormones; BCG Vaccine; Brazil; Clofazimine; Cohort Studies; COVID-19; COVID-19 Drug T | 2021 |