Page last updated: 2024-09-03

clofarabine and Recrudescence

clofarabine has been researched along with Recrudescence in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (21.74)29.6817
2010's46 (66.67)24.3611
2020's8 (11.59)2.80

Authors

AuthorsStudies
Bierings, M; Boelens, JJ; Bresters, D; de Koning, CCH; Kollen, WJ; Lankester, AC; Lindemans, CA; Nierkens, S; Versluijs, AB1
Bakkus, M; Beel, K; Bellido, M; Beverloo, HB; Biemond, BJ; Boersma, RS; Breems, DA; Cornelissen, JJ; de Haas, V; de Weerdt, O; Deeren, D; Fijnheer, R; Gadisseur, A; Halkes, CJM; Havelange, V; Homburg, CHE; Jaspers, A; Legdeur, MC; Legrand, O; Maertens, JA; Mazure, D; Rijneveld, AW; Selleslag, D; Sinnige, HAM; Terpstra, WE; Tick, LW; Triffet, A; van de Loosdrecht, AA; van der Holt, B; van der Velden, VHJ; van der Velden, WJFM; van der Wagen, LE; van Gelder, M; van Lammeren-Venema, D; van Sluis, GL1
Bakunina, K; Breems, DA; Cloos, J; Cornelissen, JJ; de Wreede, LC; Gjertsen, BT; Koster, EAS; Löwenberg, B; Manz, MG; Ossenkoppele, GJ; Pabst, T; Passweg, J; Putter, H; Valk, PJM; van der Holt, B; Versluis, J1
Agrawal, AK; Forlenza, CJ; Kernan, NA; Mauguen, A; Ramaswamy, K; Roshal, M; Shukla, N; Steinherz, PG; Sulis, ML; Trippett, T1
Alatrash, G; Alousi, AM; Anderlini, P; Bassett, R; Champlin, RE; Chen, J; Daher, M; Hosing, C; Kawedia, J; Kebriaei, P; Ledesma, C; Lu, Y; Marin, D; Mehta, R; Nieto, Y; Olson, A; Oran, B; Popat, U; Qazilbash, M; Rondon, G; Saberian, C; Shpall, EJ; Thall, PF; Valdez, BC1
Carulli, A; Catania, C; Connor, MP; Frey, NV; Freyer, CW; Gill, SI; Hexner, EO; Hollander, L; Loren, AW; Luger, SM; Mangan, JK; Martin, ME; McCurdy, SR; Perl, AE; Porter, DL; Pratz, KW; Smith, J; Stadtmauer, EA; Timlin, C; Zebrowski, AM1
Andrade, AM; Carvalho, JL; Figueiredo, ACMG; Pogue, R; Teixeira, VR1
Baruchel, A; Boëlle-Le Corfec, E; Geffriaud-Ricouard, C; Goto, H; Jeha, S; Pieters, R; Shin, HY1
Alakel, N; Bornhäuser, M; Büttner, B; Ehninger, G; Knoth, H; Kramer, M; Middeke, JM; Oertel, R; Platzbecker, U; Röllig, C; Schetelig, J; Seeling, A; Sockel, K; Stölzel, F; von Bonin, M1
Bossio, S; De Stefano, L; Gentile, M; Greco, R; Mazzone, C; Morabito, F; Morelli, R; Musolino, C; Palummo, A; Petrungaro, A; Recchia, AG; Uccello, G; Vigna, E1
Andreeff, M; Bueso-Ramos, C; Cortes, JE; Coyle, M; Daver, N; DiNardo, CD; Futreal, PA; Garcia-Manero, G; Gumbs, C; Issa, GC; Jabbour, E; Jorgensen, J; Kadia, T; Kantarjian, HM; Konopleva, M; Little, L; Morita, K; Patel, KP; Pemmaraju, N; Ravandi, F; Sasaki, K; Song, X; Takahashi, K; Thornton, R; Tippen, S; Wang, F; Wang, S; Yan, Y; Zhang, J1
Campbell, JD; Chapman, RH; Kumar, VM; McQueen, RB; Ollendorf, DA; Pearson, SD; Tice, JA; Whittington, MD1
Alary, AS; Bouscary, D; Deau, B; Fontenay, M; Hermine, O; Kosmider, O; Mondesir, J; Sibon, D; Suarez, F; Tamburini, J; Willems, L1
Cheng, YF; Liu, GL; Lu, AD; Suo, P; Wang, B; Wu, J; Zhang, LP; Zuo, YX1
Allen, CE; Beaupin, LK; Bilgi, M; Coulter, D; Garrington, T; Hicks, MJ; Jones, J; McCavit, TL; McClain, KL; Moore, C; Rivera-Ortegón, F; Shaffer, L; Simko, SJ; Stork, L; Tran, HD; Turcotte, L; Welsh, EC1
Kobos, R; Renaud, T; Shukla, N; Steinherz, LJ; Steinherz, PG1
Balakrishnan, K; Borthakur, G; Burger, J; Cortes, J; Faderl, S; Feliu, J; Ferrajoli, A; Gandhi, V; Kadia, T; Kantarjian, HM; O'Brien, S; Plunkett, W; Ravandi, F; Thomas, DA1
Advani, AS; Appelbaum, FR; Becker, M; Coutre, S; Elkins, S; McDonough, S; Mims, M; O'Donnell, M; Othus, M; Radich, J; Wood, B1
Bilger, K; Blaise, D; Chevallier, P; de La Tour, RP; Delaunay, J; El-Cheikh, J; Furst, S; Guillaume, T; Labopin, M; Lioure, B; Michallet, M; Milpied, N; Mohty, M; Moreau, P; Socié, G; Tabrizi, R; Vigouroux, S1
Abbi, KK; Claxton, DF; Ehmann, WC; Rybka, W1
Imai, K1
Aoki, T; Arakawa, Y; Hanada, R; Hayashi, M; Koh, K; Kubota, Y; Mori, M; Oyama, R1
DeAngelo, DJ; McDonnell, AM; Roberts, DA; Steensma, DP; Stone, RM; Wadleigh, M1
Dreyling, M; Engel, N; Fritsch, S; Haas, M; Hausmann, A; Hellmuth, JC; Herold, T; Hiddemann, W; Hubmann, M; Ledderose, G; Mumm, F; Prevalsek, D; Reibke, R; Rieger, CT; Tischer, J; Zoellner, AK1
Einsele, H; Grigoleit, GU; Heuschmann, PU; Hupp, E; Kapp, M; Loeffler, C; Loeffler, J; Malzahn, U; Mielke, S; Stuhler, G1
Alakel, N; Bethge, W; Bitz, U; Bornhäuser, M; Bug, G; Büttner, B; Ehninger, G; Hänel, M; Herbst, R; Klein, S; Knoth, H; Kramer, M; Middeke, JM; Morgner, A; Parmentier, S; Platzbecker, U; Röllig, C; Rösler, W; Schäfer-Eckart, K; Schaich, M; Schetelig, J; Sockel, K; Stölzel, F; Stuhler, G; Thiede, C; von Bonin, M1
Cai, Z; Cheng, Y; Ding, L; Du, X; Fang, Y; Huang, X; Jia, Y; Li, Y; Lu, A; Lu, J; Tan, F; Wang, B; Wu, J; Yu, K; Zhang, L; Zhao, L; Zuo, Y1
Ecstein-Fraisse, E; Inagaki, J; Kikuta, A; Koh, K; Kudo, K; Mizukami, H; Morimoto, T; Ogawa, C; Okamoto, Y1
Chevallier, P; Françoise, M; Grain, A; Guillaume, T; Mohty, M; Rialland, F; Sirvent, A; Strullu, M1
Ali, S; Burnett, AK; Burns, S; Cahalin, P; Clark, RE; Dennis, M; Freeman, S; Hills, RK; Kell, J; Milligan, D; Nielsen, OJ; Pocock, C; Russell, NH1
Le Jeune, C; Thomas, X1
Aoki, Y; Fujimura, J; Hoshino, A; Imai, K; Ishiwata, Y; Kajiwara, M; Kanegane, H; Mae, T; Matsumoto, K; Mitsuiki, N; Miyamoto, S; Mizutani, S; Morio, T; Nishimura, A; Takagi, M; Takikawa, K; Tanaka, M; Tomita, O; Tomizawa, D; Yanagimachi, M; Yasuhara, M1
Cairoli, R; Greco, R; Grillo, G; Mancini, V; Marbello, L; Molteni, A; Ravano, E; Riva, M; Zucchetti, E1
Brown, AW; McGregor, BA; Osswald, MB; Savona, MR1
Nabhan, C1
Capria, S; Fiocchi, C; Foà, R; Grammatico, S; Meloni, G; Vitale, A1
Albano, E; Altman, A; Arceci, R; Bomgaars, L; Gaynon, P; Goldman, S; Jeha, S; Kadota, R; Luchtman-Jones, L; Razzouk, B; Rheingold, S; Ritchey, K; Rytting, M; Steinherz, L; Steinherz, P; Stine, K1
Barberi, W; Bernardo, ME; Bertaina, A; Giraldi, E; Locatelli, F; Merli, P; Parasole, R; Pession, A; Rizzari, C; Testi, AM; Zecca, M1
Einsele, H; Grigoleit, GU; Kapp, M; Mielke, S; Stuhler, G; Tan, SM; Topp, MS; Unzicker, C1
Kobos, R; Shukla, N; Steinherz, L; Steinherz, PG1
Abonour, R; Baute, J; Cox, E; Farag, SS; Jones, D; Kane, K; Nelson, RP; Robertson, MJ; Schwartz, JE; Secrest, A; Srivastava, S; Sullivan, C; Wood, LL1
Advani, AS; Appelbaum, FR; Coutre, SE; Gundacker, HM; Lai, R; Lancet, JE; Mims, MP; Radich, JP; Sala-Torra, O; Slovak, ML; Stiff, PJ; Stuart, RK1
Agura, E; Berryman, RB; Cooper, B; Fay, J; Holmes, H; Li, S; Maisel, C; Saracino, G; Tadic-Ovcina, M; Vance, E1
Bitran, JD; Davis, N; Dewey, WM; Foss, S; Fried, W; Galvez, A; Nabhan, C; Tolzien, K; Venugopal, P1
Kwong, YL; Lee, HK; Leung, AY; Liu, HS; Sim, J; Tse, E; Yip, SF1
Appelbaum, FR; Becker, P; Estey, E; Hendrie, P; Knoebel, RW; McQuary, A; Petersdorf, S1
Caswell, M; Connor, P; Cummins, M; Kearns, PR; Mitchell, C; Motwani, J; O'Connor, D; Sibson, K; Taj, M; Vora, A; Wynn, R1
Bautista, F; Del Mar Andres, M; Fernandez-Navarro, JM; Moreno, L; Tasso, M; Verdeguer, A1
Baker, SD; Campana, D; Christensen, R; Coustan-Smith, E; Furmanski, BD; Heym, KM; Inaba, H; Li, L; Mascara, GP; Onciu, M; Pounds, SB; Pui, CH; Ribeiro, RC; Rubnitz, JE; Shurtleff, SA1
Barry, E; Borowitz, MJ; Carroll, WL; Cooper, T; Dahl, G; Gaynon, PS; Hijiya, N; Isakoff, MS; Jeha, S; Kadota, R; Maloney, K; Paul, JA; Shen, V; Silverman, LB; Steinherz, PG; Thomson, B; Thottassery, JV1
Buresova, L; Dvorakova, D; Jeziskova, I; Mayer, J; Racil, Z; Razga, F; Timilsina, S; Toskova, M1
Artz, AS; Del Cerro, P; Godley, LA; Kline, J; Larson, RA; Nguyen, V; O'Donnell, PH; Odenike, O; Rich, E; Stock, W; van Besien, K1
Amin, C; Barr, ND; Chiu, WM; Foster, MC; Ivanova, A; Richards, KL; Shea, T; van Deventer, HW; Voorhees, PM; Whitman, J1
Barisone, E; Bertorello, N; Calvillo, M; De Rossi, G; Dufour, C; Lo Nigro, L; Luciani, M; Messina, C; Miano, M; Micalizzi, C; Parasole, R; Petruzziello, F; Pistorio, A; Putti, MC; Varotto, S; Ziino, O1
Avigan, D; Collins, R; Craig, M; Faderl, S; Ganguly, S; Goldberg, S; Greiner, J; Hari, P; Huebner, D; Jagasia, M; Kantarjian, HM; Kovacsovics, T; Maris, M; Ravandi, F; Recher, C; Rizzieri, D; Schiller, G; Seiter, K; Stuart, R; Vasconcelles, M; Vey, N; Wang, ES; Wetzler, M1
Carraway, HE; Gladstone, DE; Gore, SD; Greer, JM; Karp, JE; Levis, MJ; McDevitt, MA; Pratz, KW; Ricklis, RM; Showel, MM; Smith, BD; Yun, HD; Zeidan, AM1
Abd Elmoneim, A; Arceci, RJ; Boklan, J; Cooper, T; Gore, L; Narendran, A; Ricklis, RM; Rolla, K; Scott, T1
Angelucci, E; Biagiotti, C; Borin, L; Bosi, A; Caracciolo, F; Cutini, I; Fanci, R; Gianfaldoni, G; Longo, G; Mannelli, F; Pogliani, EM; Romani, C; Scappini, B; Simonetti, F; Susini, MC1
Szer, J1
Abramson, JS; Barnes, JA; Brown, JR; Feng, Y; Fisher, DC; Hochberg, EP; Jacobsen, ED; Neuberg, DS; Takvorian, RW1
Cortes, J; Craig, A; Davis, J; Du, M; Faderl, S; Freireich, EJ; Gandhi, V; Garcia-Manero, G; Giles, F; Jeha, S; Kantarjian, H; Keating, M; O'Brien, S; Plunkett, W; Shaked, Z; Verstovsek, S1
Beran, M; Bonate, P; Cortes, J; Du, M; Estey, E; Estrov, Z; Faderl, S; Ferrajoli, A; Gandhi, V; Garcia-Manero, G; Giles, FJ; Kantarjian, H; Keating, M; Kwari, M; O'Brien, S; Plunkett, W; Wierda, W1
Albano, E; Altman, A; Arceci, RJ; Bomgaars, LR; Franklin, J; Gaynon, PS; Goldman, S; Gordon, B; Griffin, T; Jeha, S; Kadota, R; Luchtman-Jones, L; Razzouk, BI; Rheingold, S; Ritchey, K; Rytting, M; Shen, V; Steinherz, L; Steinherz, P; Weitman, S1
Bonate, PL; Du, M; Gandhi, V; Keating, MJ; Lerner, S; Nowak, B; Plunkett, W1
McCarthy, CH; McDonald, LR1
Higgins, EM; Mufti, GJ; Powell, S; Salisbury, JR; Williams, JS1
Jeha, S; Meyers, PA; Steinherz, LJ; Steinherz, PG1
Choi, J; Foss, F1
Craig, CM; Schiller, GJ1

Reviews

8 review(s) available for clofarabine and Recrudescence

ArticleYear
A systematic review on the cost-effectiveness assessment of tisagenlecleucel for refractory or relapsing B-cell acute lymphoblastic leukemia (R/R B-ALL) treatment in children and young adults.
    Cytotherapy, 2023, Volume: 25, Issue:9

    Topics: Child; Clofarabine; Cost-Benefit Analysis; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Antigen, T-Cell; Recurrence; Young Adult

2023
Patient-Level Meta-analysis of Clofarabine in Acute Lymphoblastic Leukemia.
    Advances in therapy, 2023, Volume: 40, Issue:12

    Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Clinical Trials, Phase II as Topic; Clofarabine; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

2023
[Treatment of adult Ph-negative acute lymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Boronic Acids; Bortezomib; Clofarabine; Combined Modality Therapy; Consolidation Chemotherapy; Hematopoietic Stem Cell Transplantation; Histocompatibility; HLA Antigens; Humans; Induction Chemotherapy; Maintenance Chemotherapy; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrazines; Recurrence; Transplantation Conditioning; Young Adult

2014
Treating adults with acute lymphocytic leukemia: new pharmacotherapy options.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:17

    Topics: Adenine Nucleotides; Adult; Antibodies, Monoclonal; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Disease-Free Survival; Drug Discovery; Humans; Molecular Targeted Therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleosides; Pyrimidinones; Quality of Life; Recurrence; Salvage Therapy

2016
The use of higher dose clofarabine in adults with relapsed acute lymphoblastic leukemia.
    American journal of hematology, 2009, Volume: 84, Issue:4

    Topics: Adenine Nucleotides; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation; Etoposide; Fatal Outcome; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Male; Mitoxantrone; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Recurrence; Remission Induction; Reoperation; Salvage Therapy; Vidarabine; Vincristine; Young Adult

2009
The prevalent predicament of relapsed acute myeloid leukemia.
    Hematology. American Society of Hematology. Education Program, 2012, Volume: 2012

    Topics: Adenine Nucleotides; Adult; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Decision Making; DNA Methylation; fms-Like Tyrosine Kinase 3; Gemtuzumab; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Recurrence; Remission Induction; Risk Factors; Salvage Therapy; Stem Cell Transplantation; TOR Serine-Threonine Kinases; Transplantation, Homologous

2012
Nursing considerations for clofarabine in the treatment of acute lymphoblastic leukemia in children.
    Clinical journal of oncology nursing, 2006, Volume: 10, Issue:6

    Topics: Adenine Nucleotides; Arabinonucleosides; Child; Clinical Trials, Phase II as Topic; Clofarabine; Drug Administration Schedule; Drug Monitoring; Humans; Nurse's Role; Oncology Nursing; Practice Guidelines as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Remission Induction; Survival Rate; Treatment Outcome

2006
Acute myeloid leukemia in the elderly: conventional and novel treatment approaches.
    Blood reviews, 2008, Volume: 22, Issue:4

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Arabinonucleosides; Arsenic Trioxide; Arsenicals; Azacitidine; Clofarabine; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Hydrazines; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Oxides; Recurrence; Sulfonamides

2008

Trials

33 trial(s) available for clofarabine and Recrudescence

ArticleYear
Clofarabine added to intensive treatment in adult patients with newly diagnosed ALL: the HOVON-100 trial.
    Blood advances, 2022, 02-22, Volume: 6, Issue:4

    Topics: Adult; Aged; Child; Clofarabine; Hematopoietic Stem Cell Transplantation; Humans; Neoplasm, Residual; Recurrence; Remission Induction

2022
The added value of multi-state modelling in a randomized controlled trial: The HOVON 102 study re-analyzed.
    Cancer medicine, 2022, Volume: 11, Issue:3

    Topics: Clofarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Recurrence; Remission Induction; Treatment Outcome

2022
Vorinostat Combined with Busulfan, Fludarabine, and Clofarabine Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Leukemia: Long-Term Study Outcomes.
    Transplantation and cellular therapy, 2022, Volume: 28, Issue:8

    Topics: Acute Disease; Busulfan; Clofarabine; Drug Therapy, Combination; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Recurrence; Vidarabine; Vorinostat

2022
Phase II trial of clofarabine with topotecan, vinorelbine, and thiotepa in pediatric patients with relapsed or refractory acute leukemia.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:3

    Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Thiotepa; Topotecan; Vinblastine; Vinorelbine

2014
Phase I and extension study of clofarabine plus cyclophosphamide in patients with relapsed/refractory acute lymphoblastic leukemia.
    Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:3

    Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Drug Administration Schedule; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome; Young Adult

2014
SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed/refractory acute lymphocytic leukaemia.
    British journal of haematology, 2014, Volume: 165, Issue:4

    Topics: Adenine Nucleotides; Adult; Aged; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Clofarabine; Cytarabine; Febrile Neutropenia; Female; Heart Arrest; Hematologic Diseases; Humans; Male; Middle Aged; Neoplasm, Residual; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Risk; Salvage Therapy; Sialic Acid Binding Ig-like Lectin 2; Treatment Outcome; Young Adult

2014
Results from a clofarabine-busulfan-containing, reduced-toxicity conditioning regimen prior to allogeneic stem cell transplantation: the phase 2 prospective CLORIC trial.
    Haematologica, 2014, Volume: 99, Issue:9

    Topics: Adenine Nucleotides; Adult; Aged; Antilymphocyte Serum; Arabinonucleosides; Busulfan; Clofarabine; Drug Administration Schedule; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloablative Agonists; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous

2014
Phase I/II study of clofarabine, etoposide, and mitoxantrone in patients with refractory or relapsed acute leukemia.
    Clinical lymphoma, myeloma & leukemia, 2015, Volume: 15, Issue:1

    Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Staging; Recurrence; Remission Induction; Treatment Outcome

2015
Low efficacy and high mortality associated with clofarabine treatment of relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes.
    Leukemia research, 2015, Volume: 39, Issue:2

    Topics: Adenine Nucleotides; Adult; Aged; Antimetabolites, Antineoplastic; Arabinonucleosides; Clofarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Risk Factors; Survival Rate; Time Factors

2015
Sequential therapy combining clofarabine and T-cell-replete HLA-haploidentical haematopoietic SCT is feasible and shows efficacy in the treatment of refractory or relapsed aggressive lymphoma.
    Bone marrow transplantation, 2015, Volume: 50, Issue:5

    Topics: Adenine Nucleotides; Adult; Aged; Allografts; Antimetabolites, Antineoplastic; Arabinonucleosides; Clofarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Recurrence; Retrospective Studies; Survival Rate

2015
Clofarabine salvage therapy before allogeneic hematopoietic stem cell transplantation in patients with relapsed or refractory AML: results of the BRIDGE trial.
    Leukemia, 2016, Volume: 30, Issue:2

    Topics: Adenine Nucleotides; Adult; Aged; Antimetabolites, Antineoplastic; Arabinonucleosides; Clofarabine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Recurrence; Salvage Therapy; Transplantation, Homologous

2016
Efficacy, safety and pharmacokinetics of clofarabine in Chinese pediatric patients with refractory or relapsed acute lymphoblastic leukemia: a phase II, multi-center study.
    Blood cancer journal, 2016, Feb-26, Volume: 6

    Topics: Adenine Nucleotides; Adolescent; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Drug Resistance, Neoplasm; Humans; Infant; Infant, Newborn; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome

2016
Phase 1 study of clofarabine in pediatric patients with relapsed/refractory acute lymphoblastic leukemia in Japan.
    International journal of hematology, 2016, Volume: 104, Issue:2

    Topics: Adenine Nucleotides; Adolescent; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Dose-Response Relationship, Drug; Half-Life; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome

2016
Phase II study of clofarabine in pediatric patients with refractory or relapsed acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-10, Volume: 27, Issue:26

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Agents; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Drug Resistance, Neoplasm; Female; Fever; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Nausea; Neutropenia; Recurrence; Remission Induction; Treatment Outcome; Young Adult

2009
Clofarabine, cyclophosphamide and etoposide as single-course re-induction therapy for children with refractory/multiple relapsed acute lymphoblastic leukaemia.
    British journal of haematology, 2009, Volume: 147, Issue:3

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Survival Analysis; Treatment Outcome

2009
A phase I trial of high-dose clofarabine, etoposide, and cyclophosphamide and autologous peripheral blood stem cell transplantation in patients with primary refractory and relapsed and refractory non-Hodgkin lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:7

    Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Clofarabine; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Filgrastim; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Hematopoietic Stem Cell Mobilization; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Recombinant Proteins; Recurrence; Salvage Therapy; Transplantation, Autologous; Treatment Outcome

2011
Southwest Oncology Group Study S0530: a phase 2 trial of clofarabine and cytarabine for relapsed or refractory acute lymphocytic leukaemia.
    British journal of haematology, 2010, Volume: 151, Issue:5

    Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Connective Tissue Growth Factor; Cytarabine; Female; Humans; Male; Neoplasm Proteins; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Treatment Outcome

2010
Report of a phase II study of clofarabine and cytarabine in de novo and relapsed and refractory AML patients and in selected elderly patients at high risk for anthracycline toxicity.
    The oncologist, 2011, Volume: 16, Issue:2

    Topics: Adenine Nucleotides; Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Recurrence, Local; Patient Selection; Recurrence; Remission Induction; Survival Analysis; Treatment Outcome

2011
Efficacy and safety of clofarabine in relapsed and/or refractory non-Hodgkin lymphoma, including rituximab-refractory patients.
    Cancer, 2011, Apr-01, Volume: 117, Issue:7

    Topics: Adenine Nucleotides; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Arabinonucleosides; Clofarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Recurrence; Retreatment; Rituximab; Salvage Therapy

2011
Phase I pharmacokinetic and pharmacodynamic study of the multikinase inhibitor sorafenib in combination with clofarabine and cytarabine in pediatric relapsed/refractory leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-20, Volume: 29, Issue:24

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Benzenesulfonates; Child; Clofarabine; Cytarabine; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Recurrence; Sorafenib

2011
Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia.
    Blood, 2011, Dec-01, Volume: 118, Issue:23

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Female; Humans; Infant; Kaplan-Meier Estimate; Male; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Risk Factors; RNA, Messenger; Young Adult

2011
Phase I-II study of clofarabine-melphalan-alemtuzumab conditioning for allogeneic hematopoietic cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:6

    Topics: Acute Kidney Injury; Adenine Nucleotides; Adult; Age Factors; Aged; Alemtuzumab; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Female; Glomerular Filtration Rate; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Melphalan; Middle Aged; Recurrence; Risk; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous

2012
A phase I dose-escalation study of clofarabine in combination with fractionated gemtuzumab ozogamicin in patients with refractory or relapsed acute myeloid leukemia.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:7

    Topics: Acute Disease; Adenine Nucleotides; Adult; Alanine Transaminase; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Aspartate Aminotransferases; Clofarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gemtuzumab; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Neutropenia; Recurrence; Survival Analysis; Treatment Outcome; Young Adult

2012
Clofarabine, cyclophosphamide and etoposide for the treatment of relapsed or resistant acute leukemia in pediatric patients.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:9

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Gastrointestinal Diseases; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Remission Induction; Treatment Outcome

2012
Clofarabine plus cytarabine compared with cytarabine alone in older patients with relapsed or refractory acute myelogenous leukemia: results from the CLASSIC I Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-10, Volume: 30, Issue:20

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Placebos; Recurrence

2012
Phase 1 dose-escalation trial of clofarabine followed by escalating dose of fractionated cyclophosphamide in adults with relapsed or refractory acute leukaemias.
    British journal of haematology, 2012, Volume: 158, Issue:2

    Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Remission Induction; Salvage Therapy; Treatment Outcome; Young Adult

2012
Phase I dose-escalation trial of clofarabine followed by escalating doses of fractionated cyclophosphamide in children with relapsed or refractory acute leukemias.
    Pediatric blood & cancer, 2012, Dec-15, Volume: 59, Issue:7

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; DNA Damage; Drug Administration Schedule; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Young Adult

2012
Cytarabine and clofarabine after high-dose cytarabine in relapsed or refractory AML patients.
    American journal of hematology, 2012, Volume: 87, Issue:12

    Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Treatment Outcome; Young Adult

2012
Oral clofarabine for relapsed/refractory non-Hodgkin lymphomas: results of a phase 1 study.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:9

    Topics: Adenine Nucleotides; Administration, Oral; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Arabinonucleosides; CD4 Lymphocyte Count; Clofarabine; Female; Follow-Up Studies; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Recurrence; Remission Induction; Treatment Outcome; Tumor Burden

2013
Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia.
    Blood, 2003, Oct-01, Volume: 102, Issue:7

    Topics: Adenine Nucleotides; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Survival Rate; Treatment Outcome

2003
Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias.
    Blood, 2005, Feb-01, Volume: 105, Issue:3

    Topics: Acute Disease; Adenine Nucleotides; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Karyotyping; Leukemia; Male; Middle Aged; Recurrence; Treatment Outcome

2005
Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Apr-20, Volume: 24, Issue:12

    Topics: Adenine Nucleotides; Adolescent; Adult; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Female; Humans; Infant; Infusions, Intravenous; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome

2006
Clinical and pharmacokinetic study of clofarabine in chronic lymphocytic leukemia: strategy for treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jul-01, Volume: 12, Issue:13

    Topics: Adenine Nucleotides; Aged; Arabinonucleosides; Clofarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Male; Maximum Tolerated Dose; Middle Aged; Molecular Structure; Neoplasm Staging; Recurrence; Tissue Distribution; Treatment Outcome

2006

Other Studies

28 other study(ies) available for clofarabine and Recrudescence

ArticleYear
Clofarabine-fludarabine-busulfan in HCT for pediatric leukemia: an effective, low toxicity, TBI-free conditioning regimen.
    Blood advances, 2022, 03-22, Volume: 6, Issue:6

    Topics: Busulfan; Child; Clofarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Recurrence; Vidarabine

2022
Clofarabine with topotecan, vinorelbine, and thiotepa reinduction regimen for children and young adults with relapsed AML.
    Blood advances, 2022, 04-26, Volume: 6, Issue:8

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Clofarabine; Humans; Leukemia, Myeloid, Acute; Recurrence; Thiotepa; Topotecan; Vinorelbine; Young Adult

2022
Clofarabine and Busulfan Myeloablative Conditioning in Allogeneic Hematopoietic Cell Transplantation for Patients With Active Myeloid Malignancies.
    Transplantation and cellular therapy, 2023, Volume: 29, Issue:2

    Topics: Adult; Aged; Busulfan; Clofarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myeloablative Agonists; Myeloproliferative Disorders; Recurrence; Retrospective Studies; Transplantation, Homologous; Young Adult

2023
Impact of pharmacokinetics on the toxicity and efficacy of clofarabine in patients with relapsed or refractory acute myeloid leukemia.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:12

    Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Area Under Curve; Clofarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Liver; Liver Function Tests; Male; Middle Aged; Recurrence; Skin; Treatment Outcome

2017
Ponatinib-Induced Graft-versus-Host Disease/Graft-versus-Leukemia Effect in a Patient with Philadelphia-Positive Acute Lymphoblastic Leukemia without the T315I Mutation Relapsing after Allogeneic Transplant.
    Chemotherapy, 2017, Volume: 62, Issue:6

    Topics: Adenine Nucleotides; Adult; Arabinonucleosides; Bone Marrow; Clofarabine; Cyclophosphamide; Disease-Free Survival; Female; Fusion Proteins, bcr-abl; Graft vs Host Disease; Humans; Imidazoles; Immunophenotyping; Mutation; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Protein Kinase Inhibitors; Pyridazines; Recurrence; Salvage Therapy; Transplantation, Homologous

2017
Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018, 06-20, Volume: 36, Issue:18

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Clofarabine; Cohort Studies; Cytarabine; DNA, Neoplasm; Female; High-Throughput Nucleotide Sequencing; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Recurrence; Sequence Analysis, DNA; Vidarabine

2018
Long-term Survival and Value of Chimeric Antigen Receptor T-Cell Therapy for Pediatric Patients With Relapsed or Refractory Leukemia.
    JAMA pediatrics, 2018, 12-01, Volume: 172, Issue:12

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Chronic Disease; Clofarabine; Cost-Benefit Analysis; Humans; Immunotherapy, Adoptive; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quality-Adjusted Life Years; Receptors, Antigen, T-Cell; Receptors, Chimeric Antigen; Recurrence; Treatment Outcome; Young Adult

2018
Impact of genotype in relapsed and refractory acute myeloid leukaemia patients treated with clofarabine and cytarabine: a retrospective study.
    British journal of haematology, 2019, Volume: 187, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clofarabine; Cytarabine; Drug Administration Schedule; Female; Follow-Up Studies; Genotype; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Recurrence; Retrospective Studies; Salvage Therapy; Survival Analysis; Young Adult

2019
[Therapeutic effect of clofarabine in children with relapsed or refractory acute lymphoblastic leukemia].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2013, Volume: 15, Issue:6

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Agents; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Female; Follow-Up Studies; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

2013
Clofarabine salvage therapy in refractory multifocal histiocytic disorders, including Langerhans cell histiocytosis, juvenile xanthogranuloma and Rosai-Dorfman disease.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:3

    Topics: Adenine Nucleotides; Adolescent; Antimetabolites, Antineoplastic; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Female; Histiocytosis, Langerhans-Cell; Histiocytosis, Sinus; Humans; Infant; Male; Recurrence; Salvage Therapy; Xanthogranuloma, Juvenile

2014
Clofarabine-based combination chemotherapy for relapse and refractory childhood acute lymphoblastic leukemia.
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:11

    Topics: Adenine Nucleotides; Adolescent; Analgesics, Opioid; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cefazolin; Child; Clofarabine; Cyclophosphamide; Etoposide; Fentanyl; Humans; Induction Chemotherapy; Male; Pain; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Shock, Septic; Systemic Inflammatory Response Syndrome; Treatment Outcome

2014
Control of relapsed or refractory acute myeloid leukemia by clofarabine in preparation for allogeneic stem cell transplant.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:12

    Topics: Adenine Nucleotides; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Drug Resistance, Neoplasm; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Retreatment; Retrospective Studies; Salvage Therapy; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Young Adult

2015
Sustained responses after clofarabine-based sequential allogeneic stem cell transplantation in children with high-risk, relapse and/or refractory acute myeloid leukemia or juvenile myelomonocytic leukemia: a study on behalf of the French society of bone m
    Leukemia & lymphoma, 2016, Volume: 57, Issue:12

    Topics: Adenine Nucleotides; Adolescent; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Combined Modality Therapy; Female; France; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Juvenile; Male; Recurrence; Retrospective Studies; Risk Factors; Transplantation, Homologous; Treatment Outcome; Young Adult

2016
A comparison of clofarabine with ara-C, each in combination with daunorubicin as induction treatment in older patients with acute myeloid leukaemia.
    Leukemia, 2017, Volume: 31, Issue:2

    Topics: Adenine Nucleotides; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cause of Death; Clofarabine; Cytarabine; Daunorubicin; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Survival Analysis; Treatment Outcome

2017
HLA haploidentical hematopoietic cell transplantation using clofarabine and busulfan for refractory pediatric hematological malignancy.
    International journal of hematology, 2017, Volume: 105, Issue:5

    Topics: Adenine Nucleotides; Arabinonucleosides; Busulfan; Child; Clofarabine; Female; Follow-Up Studies; Haploidy; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Leukemia; Male; Recurrence; Remission Induction; Time Factors; Transplantation Conditioning; Treatment Outcome

2017
Clofarabine-based chemotherapy as a bridge to transplant in the setting of refractory or relapsed acute myeloid leukemia, after at least one previous unsuccessful salvage treatment containing fludarabine: a single institution experience.
    International journal of hematology, 2017, Volume: 105, Issue:6

    Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Allografts; Arabinonucleosides; Clofarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Retrospective Studies; Salvage Therapy; Vidarabine

2017
Clofarabine in relapsed lymphoma: what is the optimal dose?
    Leukemia & lymphoma, 2009, Volume: 50, Issue:7

    Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Data Interpretation, Statistical; Drug Administration Schedule; Humans; Lymphoma, Non-Hodgkin; Medical Oncology; Recurrence; Remission Induction; Research Design

2009
Advanced Philadelphia chromosome positive acute lymphoblastic leukemia patients relapsed after treatment with tyrosine-kinase inhibitors: successful response to clofarabine and cyclophosphamide.
    Haematologica, 2009, Volume: 94, Issue:10

    Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Female; Humans; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Recurrence

2009
Clofarabine-based salvage chemotherapy for relapsed or refractory acute leukemia before allogeneic stem cell transplantation: results from a case series.
    Leukemia & lymphoma, 2009, Volume: 50, Issue:12

    Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Male; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome

2009
Remission re-induction chemotherapy with clofarabine, topotecan, thiotepa, and vinorelbine for patients with relapsed or refractory leukemia.
    Pediatric blood & cancer, 2010, Volume: 54, Issue:5

    Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Thiotepa; Topotecan; Vinblastine; Vinorelbine

2010
Clofarabine and high-dose cytosine arabinoside in the treatment of refractory or relapsed acute myeloid leukaemia.
    Annals of hematology, 2011, Volume: 90, Issue:11

    Topics: Adenine Nucleotides; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Treatment Outcome; Young Adult

2011
Infections in relapsed or refractory acute myeloid leukemia patients given clofarabine+cytarabine.
    Leukemia research, 2011, Volume: 35, Issue:9

    Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Drug Resistance, Neoplasm; Humans; Infections; Leukemia, Myeloid, Acute; Recurrence; Treatment Failure

2011
Early UK experience in the use of clofarabine in the treatment of relapsed and refractory paediatric acute lymphoblastic leukaemia.
    British journal of haematology, 2011, Volume: 154, Issue:4

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Drug Evaluation; Female; Humans; Infant; Infant, Newborn; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome

2011
Institutional experience with clofarabine and cytarabine in relapsed pediatric acute myeloid leukemia.
    Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:1

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Recurrence; Retrospective Studies; Transplantation, Homologous

2012
Treatment of molecular relapse in patients with acute myeloid leukemia using clofarabine monotherapy.
    American journal of hematology, 2012, Volume: 87, Issue:2

    Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Oncogene Proteins, Fusion; Recurrence; Remission Induction; Survival Analysis; Treatment Outcome

2012
Saccharomyces cerevisiae emboli in an immunocompromised patient with relapsed acute myeloid leukaemia.
    Clinical and experimental dermatology, 2007, Volume: 32, Issue:4

    Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Dermatomycoses; Female; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Middle Aged; Opportunistic Infections; Recurrence; Saccharomyces cerevisiae

2007
Clofarabine induced durable complete remission in heavily pretreated adolescents with relapsed and refractory leukemia.
    Journal of pediatric hematology/oncology, 2007, Volume: 29, Issue:9

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Arabinonucleosides; Clofarabine; Female; Humans; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction

2007
Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia.
    The Yale journal of biology and medicine, 2006, Volume: 79, Issue:3-4

    Topics: Adenine Nucleotides; Adult; Arabinonucleosides; Bone Marrow Neoplasms; Clinical Trials as Topic; Clofarabine; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Immunophenotyping; Leukemia-Lymphoma, Adult T-Cell; Male; Recurrence; Skin Neoplasms; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome

2006