Page last updated: 2024-09-03

clofarabine and Breast Neoplasms

clofarabine has been researched along with Breast Neoplasms in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (33.33)	29.6817
2010's	4 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fabianowska-Majewska, K; Kaufman-Szymczyk, A; Lubecka, K	1
Cebula-Obrzut, B; Fabianowska-Majewska, K; Kaufman-Szymczyk, A; Lubecka, K; Smolewski, P; Szemraj, J	1
Cebula-Obrzut, B; Fabianowska-Majewska, K; Kaufman-Szymczyk, A; Lubecka-Pietruszewska, K; Smolewski, P; Stefanska, B	2
Beijnen, J; Borst, P; de Haas, M; de Wolf, C; Jansen, R; van de Wetering, K; Wijnholds, J; Yamaguchi, H	1
Cortes, J; Du, M; Faderl, S; Gandhi, V; Giles, F; Ibrahim, N; Jeha, S; Kantarjian, HM; Keating, M; Khuri, F; Kozuch, P; McLaughlin, P; O'Brien, S; Plunkett, W; Rios, MB	1

Trials

1 trial(s) available for clofarabine and Breast Neoplasms

Article	Year
Phase I clinical and pharmacology study of clofarabine in patients with solid and hematologic cancers. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-15, Volume: 21, Issue:6 Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Agents; Arabinonucleosides; Bone Marrow; Breast Neoplasms; Clofarabine; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Hematologic Neoplasms; Humans; Infusions, Intravenous; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Liver; Lung Neoplasms; Male; Middle Aged; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome	2003

Article

Year

Phase I clinical and pharmacology study of clofarabine in patients with solid and hematologic cancers.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-15, Volume: 21, Issue:6

Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Agents; Arabinonucleosides; Bone Marrow; Breast Neoplasms; Clofarabine; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Hematologic Neoplasms; Humans; Infusions, Intravenous; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Liver; Lung Neoplasms; Male; Middle Aged; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome

2003

Other Studies

5 other study(ies) available for clofarabine and Breast Neoplasms

Article	Year
Inhibition of breast cancer cell growth by the combination of clofarabine and sulforaphane involves epigenetically mediated CDKN2A upregulation. Nucleosides, nucleotides & nucleic acids, 2018, Volume: 37, Issue:5 Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Breast Neoplasms; Cell Line, Tumor; Clofarabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Isothiocyanates; Molecular Targeted Therapy; Signal Transduction; Sulfoxides; Up-Regulation	2018
Novel Clofarabine-Based Combinations with Polyphenols Epigenetically Reactivate Retinoic Acid Receptor Beta, Inhibit Cell Growth, and Induce Apoptosis of Breast Cancer Cells. International journal of molecular sciences, 2018, Dec-10, Volume: 19, Issue:12 Topics: Apoptosis; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Clofarabine; Cyclin-Dependent Kinase Inhibitor p21; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genistein; Humans; Inhibitory Concentration 50; Polyphenols; Promoter Regions, Genetic; PTEN Phosphohydrolase; Receptors, Retinoic Acid; Transcription, Genetic; Up-Regulation	2018
Clofarabine, a novel adenosine analogue, reactivates DNA methylation-silenced tumour suppressor genes and inhibits cell growth in breast cancer cells. European journal of pharmacology, 2014, Jan-15, Volume: 723 Topics: Adenine Nucleotides; Adenomatous Polyposis Coli Protein; Antimetabolites, Antineoplastic; Apoptosis; Arabinonucleosides; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Clofarabine; Cyclin-Dependent Kinase Inhibitor p21; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Female; Humans; Promoter Regions, Genetic; PTEN Phosphohydrolase; Receptors, Retinoic Acid; RNA, Messenger; Tumor Suppressor Protein p53	2014
Sulforaphane Alone and in Combination with Clofarabine Epigenetically Regulates the Expression of DNA Methylation-Silenced Tumour Suppressor Genes in Human Breast Cancer Cells. Journal of nutrigenetics and nutrigenomics, 2015, Volume: 8, Issue:2 Topics: Adenine Nucleotides; Arabinonucleosides; Breast Neoplasms; Cell Line, Tumor; Clofarabine; DNA Methylation; Epigenesis, Genetic; Female; Genes, Tumor Suppressor; Humans; Isothiocyanates; Sulfoxides	2015
Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides. Molecular cancer therapeutics, 2008, Volume: 7, Issue:9 Topics: Adenine Nucleotides; Adenosine Monophosphate; Animals; Antineoplastic Agents; Arabinonucleosides; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Breast Neoplasms; Cell Line; Cladribine; Clofarabine; Dogs; Drug Resistance, Neoplasm; Gene Expression Regulation; Humans; Mercaptopurine; Mice; Neoplasm Proteins; Nucleosides; RNA, Messenger; Transfection; Transport Vesicles	2008