clofarabine has been researched along with Acute Lymphoid Leukemia in 84 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 31 (36.90) | 29.6817 |
| 2010's | 42 (50.00) | 24.3611 |
| 2020's | 11 (13.10) | 2.80 |
| Authors | Studies |
|---|---|
| Baer, MR; Blackford, AL; Carraway, HE; Dezern, A; Ghosh, N; Gojo, I; Gore, L; Gore, SD; Greer, J; Karp, JE; Lee, MJ; Lee, S; Levis, MJ; Piekarz, R; Pratz, KW; Sawalha, Y; Smith, BD; Tomita, Y; Trepel, JB; Yuno, A | 1 |
| Berger, W; Brettner, R; Bruchbacher, A; Clozel, T; Compérat, E; Elemento, O; Ertl, IE; Gutmann, M; Haitel, A; Hassler, MR; Ilijazi, D; Koren, A; Kronabitter, H; Kubicek, S; Lardeau, CH; Lemberger, U; Mohr, T; Oszwald, A; Shariat, SF; Vician, P; Wasinger, G; Zeitler, G | 1 |
| Campana, D; Cheng, C; Choi, J; Coustan-Smith, E; Gruber, TA; Inaba, H; Jeha, S; Metzger, ML; Pauley, JL; Pei, D; Pui, CH; Raimondi, SC; Ribeiro, RC; Rubnitz, JE; Swanson, HD | 1 |
| Bhatia, M; Foti, A; George, D; Hijiya, N; Levine, J; Satwani, P; Seidel, D; Stein, D; Williams, O | 1 |
| Andrade, AM; Carvalho, JL; Figueiredo, ACMG; Pogue, R; Teixeira, VR | 1 |
| Baruchel, A; Boëlle-Le Corfec, E; Geffriaud-Ricouard, C; Goto, H; Jeha, S; Pieters, R; Shin, HY | 1 |
| Boddy, AV; Haber, M; Langenhorst, J; Lau, L; Lock, RB; Marshall, GM; Punt, AM; Sia, KCS; Span, M; Sutton, R; Trahair, T; Tyrrell, V; van Maarseveen, E; Venn, N; Xie, J | 1 |
| Kaufman-Szymczyk, A; Lubecka, K | 1 |
| Dykes, J; Håkansson, Y; Król, L; Pronk, C; Toporski, J; Turkiewicz, D | 1 |
| Cho, B; Cho, H; Choi, JY; Chung, NG; Hahn, SM; Han, JW; Hong, CR; Hong, KT; Im, HJ; Jang, PS; Jeon, IS; Kang, HJ; Kim, H; Kim, S; Koh, KN; Koo, HH; Kook, H; Lee, JW; Lim, YT; Lyu, CJ; Seo, JJ; Shin, HY; Yang, EJ; Yoo, KH | 1 |
| Borkhardt, A; Dilloo, D; Escherich, G; Faber, J; Feuchtinger, T; Horstmann, MA; Imschweiler, T; Jorch, N; Pekrun, A; Schmid, I; Schramm, F; Spohn, M; Zimmermann, M; Zur Stadt, U | 1 |
| Isaac McGraw, B; Savaşan, S; Sweeney, C | 1 |
| Bossio, S; De Stefano, L; Gentile, M; Greco, R; Mazzone, C; Morabito, F; Morelli, R; Musolino, C; Palummo, A; Petrungaro, A; Recchia, AG; Uccello, G; Vigna, E | 1 |
| Borowitz, M; Burke, MJ; Carroll, AJ; Carroll, WL; Chen, S; Devidas, M; Gore, L; Heerema, NA; Hilden, JM; Hunger, SP; Larsen, EC; Loh, ML; Raetz, EA; Salzer, WL; Winick, NJ; Wood, B | 1 |
| Campbell, JD; Chapman, RH; Kumar, VM; McQueen, RB; Ollendorf, DA; Pearson, SD; Tice, JA; Whittington, MD | 1 |
| Cheng, YF; Liu, GL; Lu, AD; Suo, P; Wang, B; Wu, J; Zhang, LP; Zuo, YX | 1 |
| Bücklein, V; Engel, N; Fritsch, S; Hausmann, A; Hill, W; Hubmann, M; Ledderose, G; Prevalsek, D; Schulz, C; Stemmler, HJ; Tischer, J; Zoellner, AK | 1 |
| Escherich, G; Horstmann, MA; Zimmermann, M; Zur Stadt, U | 1 |
| Kobos, R; Renaud, T; Shukla, N; Steinherz, LJ; Steinherz, PG | 1 |
| Burke, MJ; Gorman, MF; Gossai, N; Karras, NA; Patel, NJ; Verneris, MR | 1 |
| Balakrishnan, K; Borthakur, G; Burger, J; Cortes, J; Faderl, S; Feliu, J; Ferrajoli, A; Gandhi, V; Kadia, T; Kantarjian, HM; O'Brien, S; Plunkett, W; Ravandi, F; Thomas, DA | 1 |
| Bolognia, J; Marks, P; Podoltsev, N; Zhang, B | 1 |
| Böhm, A; Bojic, M; Greinix, H; Hauswirth, A; Jaeger, U; Kalhs, P; Keil, F; Rabitsch, W; Schellongowski, P; Sliwa, T; Sperr, WR; Valent, P; Wöhrer, S; Worel, N | 1 |
| Bilger, K; Blaise, D; Chevallier, P; de La Tour, RP; Delaunay, J; El-Cheikh, J; Furst, S; Guillaume, T; Labopin, M; Lioure, B; Michallet, M; Milpied, N; Mohty, M; Moreau, P; Socié, G; Tabrizi, R; Vigouroux, S | 1 |
| Dombret, H; Huguet, F; Ifrah, N; Leguay, T; Pigneux, A; Raffoux, E; Rousselot, P; Vey, N | 1 |
| Imai, K | 1 |
| Aoki, T; Arakawa, Y; Hanada, R; Hayashi, M; Koh, K; Kubota, Y; Mori, M; Oyama, R | 1 |
| Pieters, R; Schneider, P; Stam, RW; Stumpel, DJ | 1 |
| Alyea, E; Ballen, KK; Chen, YB; Cutler, C; Dey, BR; Driscoll, J; El-Jawahri, A; Ho, VT; Hunnewell, C; Li, S; McAfee, SL; Poliquin, C; Saylor, M; Soiffer, RJ; Spitzer, TR | 1 |
| Baruchel, A; Bertrand, Y; Brethon, B; Cave, H; Galambrun, C; Gandemer, V; Leverger, G; Nelken, B; Plat, G; Rohrlich, P; Schmitt, C; Thomas, C; Vérité, C | 1 |
| Aoki, Y; Imai, K; Ishiwata, Y; Kajiwara, M; Miyawaki, R; Mizutani, S; Morio, T; Takagi, M; Tomizawa, D; Yasuhara, M | 1 |
| Chiang, AK; Ha, SY; Lee, V; Li, CK; Liu, AP | 1 |
| Goto, H; Goto, S; Yokosuka, T | 1 |
| Cai, Z; Cheng, Y; Ding, L; Du, X; Fang, Y; Huang, X; Jia, Y; Li, Y; Lu, A; Lu, J; Tan, F; Wang, B; Wu, J; Yu, K; Zhang, L; Zhao, L; Zuo, Y | 1 |
| Ecstein-Fraisse, E; Inagaki, J; Kikuta, A; Koh, K; Kudo, K; Mizukami, H; Morimoto, T; Ogawa, C; Okamoto, Y | 1 |
| Le Jeune, C; Thomas, X | 1 |
| Gilbert, KS; Parker, WB; Shaddix, SC; Shepherd, RV; Waud, WR | 1 |
| Vij, R | 1 |
| Brock, R; Ganser, A; Hilderink, J; Müller, I; Roth, G; van Galen, JC; van Leeuwen, FN; Wammes, JJ; Wiesmüller, KH | 1 |
| Capria, S; Fiocchi, C; Foà, R; Grammatico, S; Meloni, G; Vitale, A | 1 |
| Abichandani, R; Barry, E; Carroll, WL; Chu, R; Cooper, T; Gaynon, P; Hijiya, N; Jeha, S; Kadota, R; Rytting, M; Shen, V; Silverman, L; Steinherz, P; Thomson, B | 1 |
| Barberi, W; Bernardo, ME; Bertaina, A; Giraldi, E; Locatelli, F; Merli, P; Parasole, R; Pession, A; Rizzari, C; Testi, AM; Zecca, M | 1 |
| Jeha, S | 1 |
| Einsele, H; Grigoleit, GU; Kapp, M; Mielke, S; Stuhler, G; Tan, SM; Topp, MS; Unzicker, C | 1 |
| Faderl, S | 1 |
| Baytan, B; Dönmez, O; Gunes, AM; Ozdemir, O | 1 |
| Kobos, R; Shukla, N; Steinherz, L; Steinherz, PG | 1 |
| Advani, AS; Appelbaum, FR; Coutre, SE; Gundacker, HM; Lai, R; Lancet, JE; Mims, MP; Radich, JP; Sala-Torra, O; Slovak, ML; Stiff, PJ; Stuart, RK | 1 |
| Abonour, R; Baute, J; Cox, E; Farag, SS; Jones, DR; Kane, K; Nelson, RP; Robertson, MJ; Schwartz, JE; Secrest, A; Srivastava, S; Sullivan, C; Wood, LL | 1 |
| Dressel, A; Kwari, M; McGreal, AM | 1 |
| Sekeres, MA; Tiu, RV; Traina, F | 1 |
| Caswell, M; Connor, P; Cummins, M; Kearns, PR; Mitchell, C; Motwani, J; O'Connor, D; Sibson, K; Taj, M; Vora, A; Wynn, R | 1 |
| Barry, E; Borowitz, MJ; Carroll, WL; Cooper, T; Dahl, G; Gaynon, PS; Hijiya, N; Isakoff, MS; Jeha, S; Kadota, R; Maloney, K; Paul, JA; Shen, V; Silverman, LB; Steinherz, PG; Thomson, B; Thottassery, JV | 1 |
| Barisone, E; Bertorello, N; Calvillo, M; De Rossi, G; Dufour, C; Lo Nigro, L; Luciani, M; Messina, C; Miano, M; Micalizzi, C; Parasole, R; Petruzziello, F; Pistorio, A; Putti, MC; Varotto, S; Ziino, O | 1 |
| Arceci, RJ; Barry, E; Hijiya, N | 1 |
| Barba, P; Bueno, J; Calbacho, M; Fernández, P; García-Boyero, R; Gonzalez, J; Martínez-Sánchez, P; Ribera, JM; Sampol, A; Serrano, J | 1 |
| Carraway, HE; Gladstone, DE; Gore, SD; Greer, JM; Karp, JE; Levis, MJ; McDevitt, MA; Pratz, KW; Ricklis, RM; Showel, MM; Smith, BD; Yun, HD; Zeidan, AM | 1 |
| Buchholz, S; Chevallier, P; Ciceri, F; Faul, C; Finke, J; Ganser, A; Guillerm, G; Huynh, A; Kolb, HJ; Labopin, M; Lioure, B; Mohty, M; Nagler, A; Polge, E; Schubert, J | 1 |
| Alousi, A; Andersson, BS; Basset, R; Champlin, RE; Ciurea, S; de Lima, M; Hosing, C; Jones, RB; Kebriaei, P; Khouri, I; Ledesma, C; Nieto, Y; Parmar, S; Popat, U; Qazilbash, M; Shpall, EJ | 1 |
| Abd Elmoneim, A; Arceci, RJ; Boklan, J; Cooper, T; Gore, L; Narendran, A; Ricklis, RM; Rolla, K; Scott, T | 1 |
| Ahmed, AB; Bruserud, O; Hatfield, KJ; Kittang, AO; Reikvam, H; Sjo, M; Tvedt, TH | 1 |
| Adlard, K; Alonzo, TA; Cooper, TM; Gamis, AS; Gerbing, R; Perentesis, J; Raetz, E; Razzouk, BI; Whitlock, JA | 1 |
| Akinaga, S; Shimizu, M; Takahashi, T | 1 |
| Cortes, J; Du, M; Faderl, S; Gandhi, V; Giles, F; Ibrahim, N; Jeha, S; Kantarjian, HM; Keating, M; Khuri, F; Kozuch, P; McLaughlin, P; O'Brien, S; Plunkett, W; Rios, MB | 1 |
| Cortes, J; Craig, A; Davis, J; Du, M; Faderl, S; Freireich, EJ; Gandhi, V; Garcia-Manero, G; Giles, F; Jeha, S; Kantarjian, H; Keating, M; O'Brien, S; Plunkett, W; Shaked, Z; Verstovsek, S | 1 |
| Bumgardner, A; Chiao, N; Duvic, M | 1 |
| Brandt, M; Chan, KW; Gandhi, V; Jeha, S; Kantarjian, H; Keating, M; Madden, R; McDonald, L; Plunkett, W; Ramirez, I; Rytting, M | 1 |
| Ayres, M; Bonate, P; Du, M; Faderl, S; Gandhi, V; Kantarjian, H; Keating, MJ; Plunkett, W; Rios, MB | 1 |
| Bonate, PL; Craig, A; Gandhi, V; Gaynon, P; Jeha, S; Kadota, R; Lam, GN; Plunkett, W; Razzouk, B; Rytting, M; Steinherz, P; Weitman, S | 1 |
| Cooper, T; Gandhi, V; Kantarjian, H; Plunkett, W | 1 |
| Jeha, S; Kirkpatrick, P; Pui, CH | 1 |
| Jeha, S; Pui, CH | 1 |
| Curran, MP; Perry, CM | 1 |
| Kline, JP; Larson, RA | 1 |
| Albano, E; Altman, A; Arceci, RJ; Bomgaars, LR; Franklin, J; Gaynon, PS; Goldman, S; Gordon, B; Griffin, T; Jeha, S; Kadota, R; Luchtman-Jones, L; Razzouk, BI; Rheingold, S; Ritchey, K; Rytting, M; Shen, V; Steinherz, L; Steinherz, P; Weitman, S | 1 |
| Gandhi, V; Plunkett, W | 1 |
| Arthaud, L; Bonate, PL; Cantrell, WR; Secrist, JA; Stephenson, K; Weitman, S | 1 |
| McCarthy, CH; McDonald, LR | 1 |
| Jeha, S; Kantarjian, H | 1 |
| Beesley, AH; Cummings, AJ; de Klerk, NH; Firth, MJ; Ford, J; Freitas, JR; Kees, UR; Palmer, ML; Perera, KU; Weller, RE | 1 |
| Balakrishnan, K; Briel, J; Carraway, H; Gandhi, V; Gore, SD; Greer, J; Karp, JE; Levis, MJ; McDevitt, MA; Ricklis, RM; Smith, BD | 1 |
| Jeha, S; Meyers, PA; Steinherz, LJ; Steinherz, PG | 1 |
| Johnston, DL; Mandel, KM | 1 |
| Larson, RA | 1 |
17 review(s) available for clofarabine and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
A systematic review on the cost-effectiveness assessment of tisagenlecleucel for refractory or relapsing B-cell acute lymphoblastic leukemia (R/R B-ALL) treatment in children and young adults.
Topics: Child; Clofarabine; Cost-Benefit Analysis; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Antigen, T-Cell; Recurrence; Young Adult | 2023 |
Patient-Level Meta-analysis of Clofarabine in Acute Lymphoblastic Leukemia.
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Clinical Trials, Phase II as Topic; Clofarabine; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2023 |
Clofarabine for the treatment of adult acute lymphoid leukemia: the Group for Research on Adult Acute Lymphoblastic Leukemia intergroup.
Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Clofarabine; Dose-Response Relationship, Drug; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Stem Cell Transplantation; Treatment Outcome | 2015 |
[Treatment of adult Ph-negative acute lymphoblastic leukemia].
Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Boronic Acids; Bortezomib; Clofarabine; Combined Modality Therapy; Consolidation Chemotherapy; Hematopoietic Stem Cell Transplantation; Histocompatibility; HLA Antigens; Humans; Induction Chemotherapy; Maintenance Chemotherapy; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrazines; Recurrence; Transplantation Conditioning; Young Adult | 2014 |
Treating adults with acute lymphocytic leukemia: new pharmacotherapy options.
Topics: Adenine Nucleotides; Adult; Antibodies, Monoclonal; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Disease-Free Survival; Drug Discovery; Humans; Molecular Targeted Therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleosides; Pyrimidinones; Quality of Life; Recurrence; Salvage Therapy | 2016 |
Recent progress in the treatment of acute lymphoblastic leukemia: clofarabine.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2009 |
Clofarabine for myelodysplastic syndromes.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Humans; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2011 |
Clofarabine in pediatric acute leukemia: current findings and issues.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clinical Trials as Topic; Clofarabine; Cyclophosphamide; Cytarabine; Etoposide; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2012 |
High-dose etoposide in allogeneic stem cell transplantation.
Topics: Adenine Nucleotides; Anthracyclines; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Busulfan; Carboplatin; Carmustine; Clinical Trials as Topic; Clofarabine; Cyclophosphamide; Dose Fractionation, Radiation; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Leukemia; Leukemia, Myeloid, Acute; Lomustine; Mucositis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, Adjuvant; Severity of Illness Index; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2012 |
Clofarabine-induced acral erythema during the treatment of patients with myelodysplasia and acute leukemia: report of two cases.
Topics: Adenine Nucleotides; Adolescent; Arabinonucleosides; Clofarabine; Dose-Response Relationship, Drug; Erythema; Female; Foot Dermatoses; Hand Dermatoses; Humans; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2003 |
Clofarabine.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Child; Clinical Trials as Topic; Clofarabine; DNA; Humans; Nucleic Acid Synthesis Inhibitors; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ribonucleotide Reductases; Treatment Outcome | 2005 |
Clofarabine in the treatment of acute myeloid leukaemia and acute lymphoblastic leukaemia: a review.
Topics: Adenine Nucleotides; Arabinonucleosides; Clofarabine; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2005 |
Clofarabine and nelarabine: two new purine nucleoside analogs.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Humans; Leukemia; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2006 |
Discovery and development of clofarabine: a nucleoside analogue for treating cancer.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Drug Approval; Drug Design; Humans; Leukemia, Myeloid, Acute; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2006 |
Nursing considerations for clofarabine in the treatment of acute lymphoblastic leukemia in children.
Topics: Adenine Nucleotides; Arabinonucleosides; Child; Clinical Trials, Phase II as Topic; Clofarabine; Drug Administration Schedule; Drug Monitoring; Humans; Nurse's Role; Oncology Nursing; Practice Guidelines as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Remission Induction; Survival Rate; Treatment Outcome | 2006 |
Clofarabine for the treatment of acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2007 |
Three new drugs for acute lymphoblastic leukemia: nelarabine, clofarabine, and forodesine.
Topics: Adenine Nucleotides; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clofarabine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Pyrimidinones | 2007 |
29 trial(s) available for clofarabine and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Phase 1 study of the histone deacetylase inhibitor entinostat plus clofarabine for poor-risk Philadelphia chromosome-negative (newly diagnosed older adults or adults with relapsed refractory disease) acute lymphoblastic leukemia or biphenotypic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Lineage; Clofarabine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Histone Deacetylase Inhibitors; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Pyridines; Salvage Therapy; Young Adult | 2021 |
The combination of clofarabine, etoposide, and cyclophosphamide shows limited efficacy as a bridge to transplant for children with refractory acute leukemia: results of a monitored prospective study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Treatment Outcome; Young Adult | 2021 |
Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acut
Topics: Acute Disease; Antineoplastic Agents; Child; Clofarabine; Cytarabine; Disease-Free Survival; Humans; Lymphoma, Non-Hodgkin; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2022 |
Toxicity associated with intensive postinduction therapy incorporating clofarabine in the very high-risk stratum of patients with newly diagnosed high-risk B-lymphoblastic leukemia: A report from the Children's Oncology Group study AALL1131.
Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Child; Child, Preschool; Clofarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Pancreatitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Severity of Illness Index; Young Adult | 2018 |
Clofarabine in combination with pegylated asparaginase in the frontline treatment of childhood acute lymphoblastic leukaemia: a feasibility report from the CoALL 08-09 trial.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Asparaginase; Child; Child, Preschool; Clofarabine; Drug Administration Schedule; Female; Humans; Male; Neoplasm, Residual; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2013 |
Phase II trial of clofarabine with topotecan, vinorelbine, and thiotepa in pediatric patients with relapsed or refractory acute leukemia.
Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Thiotepa; Topotecan; Vinblastine; Vinorelbine | 2014 |
Phase I and extension study of clofarabine plus cyclophosphamide in patients with relapsed/refractory acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Drug Administration Schedule; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome; Young Adult | 2014 |
Results from a clofarabine-busulfan-containing, reduced-toxicity conditioning regimen prior to allogeneic stem cell transplantation: the phase 2 prospective CLORIC trial.
Topics: Adenine Nucleotides; Adult; Aged; Antilymphocyte Serum; Arabinonucleosides; Busulfan; Clofarabine; Drug Administration Schedule; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloablative Agonists; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous | 2014 |
Phase II Trial of Reduced-Intensity Busulfan/Clofarabine Conditioning with Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Acute Lymphoid Leukemia.
Topics: Adenine Nucleotides; Adult; Aged; Arabinonucleosides; Busulfan; Chronic Disease; Clofarabine; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning | 2016 |
A Phase I Study of Clofarabine With Multiagent Chemotherapy in Childhood High Risk Relapse of Acute Lymphoblastic Leukemia (VANDEVOL Study of the French SFCE Acute Leukemia Committee).
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Asparaginase; Child; Child, Preschool; Clofarabine; Dexamethasone; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Male; Maximum Tolerated Dose; Mitoxantrone; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Young Adult | 2016 |
Efficacy, safety and pharmacokinetics of clofarabine in Chinese pediatric patients with refractory or relapsed acute lymphoblastic leukemia: a phase II, multi-center study.
Topics: Adenine Nucleotides; Adolescent; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Drug Resistance, Neoplasm; Humans; Infant; Infant, Newborn; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome | 2016 |
Phase 1 study of clofarabine in pediatric patients with relapsed/refractory acute lymphoblastic leukemia in Japan.
Topics: Adenine Nucleotides; Adolescent; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Dose-Response Relationship, Drug; Half-Life; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome | 2016 |
A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia.
Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Salvage Therapy; Treatment Outcome; Young Adult | 2009 |
Clofarabine, cyclophosphamide and etoposide as single-course re-induction therapy for children with refractory/multiple relapsed acute lymphoblastic leukaemia.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Survival Analysis; Treatment Outcome | 2009 |
Southwest Oncology Group Study S0530: a phase 2 trial of clofarabine and cytarabine for relapsed or refractory acute lymphocytic leukaemia.
Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Connective Tissue Growth Factor; Cytarabine; Female; Humans; Male; Neoplasm Proteins; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Treatment Outcome | 2010 |
Phase I trial and pharmacokinetic study of high-dose clofarabine and busulfan and allogeneic stem cell transplantation in adults with high-risk and refractory acute leukemia.
Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Busulfan; Clofarabine; Combined Modality Therapy; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Stem Cell Transplantation; Survival Rate; Tissue Distribution; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Young Adult | 2011 |
Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Female; Humans; Infant; Kaplan-Meier Estimate; Male; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Risk Factors; RNA, Messenger; Young Adult | 2011 |
Clofarabine, cyclophosphamide and etoposide for the treatment of relapsed or resistant acute leukemia in pediatric patients.
Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Gastrointestinal Diseases; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Remission Induction; Treatment Outcome | 2012 |
Phase 1 dose-escalation trial of clofarabine followed by escalating dose of fractionated cyclophosphamide in adults with relapsed or refractory acute leukaemias.
Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Remission Induction; Salvage Therapy; Treatment Outcome; Young Adult | 2012 |
Clofarabine combined with busulfan provides excellent disease control in adult patients with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation.
Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Busulfan; Clofarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Transplantation Conditioning; Young Adult | 2012 |
Phase I dose-escalation trial of clofarabine followed by escalating doses of fractionated cyclophosphamide in children with relapsed or refractory acute leukemias.
Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; DNA Damage; Drug Administration Schedule; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Young Adult | 2012 |
Phase I/II trial of clofarabine and cytarabine in children with relapsed/refractory acute lymphoblastic leukemia (AAML0523): a report from the Children's Oncology Group.
Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Infant; Kaplan-Meier Estimate; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult | 2013 |
Phase I clinical and pharmacology study of clofarabine in patients with solid and hematologic cancers.
Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Agents; Arabinonucleosides; Bone Marrow; Breast Neoplasms; Clofarabine; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Hematologic Neoplasms; Humans; Infusions, Intravenous; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Liver; Lung Neoplasms; Male; Middle Aged; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2003 |
Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia.
Topics: Adenine Nucleotides; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Survival Rate; Treatment Outcome | 2003 |
Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia.
Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Agents; Arabinonucleosides; Child; Child, Preschool; Clofarabine; DNA, Neoplasm; Drug Tolerance; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2004 |
Pharmacokinetics and pharmacodynamics of plasma clofarabine and cellular clofarabine triphosphate in patients with acute leukemias.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clofarabine; DNA; Dose-Response Relationship, Drug; Humans; Leukemia; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Models, Chemical; Neoplastic Cells, Circulating; Oligonucleotides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors | 2003 |
Clofarabine in adult acute leukemias: clinical success and pharmacokinetics.
Topics: Adenine Nucleotides; Adult; Antimetabolites, Antineoplastic; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Cohort Studies; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Models, Chemical; Myelodysplastic Syndromes; Neoplasm Metastasis; Neoplasms; Nucleosides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2004 |
Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Adolescent; Adult; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Female; Humans; Infant; Infusions, Intravenous; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome | 2006 |
A phase 1 clinical-laboratory study of clofarabine followed by cyclophosphamide for adults with refractory acute leukemias.
Topics: Acute Disease; Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arabinonucleosides; Clofarabine; Cyclophosphamide; DNA Damage; DNA Repair; Female; Histones; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Recurrence, Local; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2007 |
38 other study(ies) available for clofarabine and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound.
Topics: Animals; Carcinoma, Transitional Cell; Clofarabine; Early Detection of Cancer; Humans; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Urinary Bladder Neoplasms | 2022 |
Clofarabine treatment of KMT2Ar infantile patients with acute lymphoblastic leukemia in St. Jude Total Therapy Study 16.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clofarabine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2022 |
Clofarabine for Lymphodepletion Before CAR-T-Cell Infusion: A Brief Case Report.
Topics: Clofarabine; Humans; Immunotherapy, Adoptive; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; T-Lymphocytes | 2023 |
Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clofarabine; Cyclophosphamide; Etoposide; Humans; Mice; Precision Medicine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Xenograft Model Antitumor Assays | 2020 |
The effects of clofarabine in ALL inhibition through DNA methylation regulation.
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Clofarabine; Cyclin-Dependent Kinase Inhibitor p21; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic | 2020 |
Effectiveness and Safety of Clofarabine Monotherapy or Combination Treatment in Relapsed/Refractory Childhood Acute Lymphoblastic Leukemia: A Pragmatic, Non-interventional Study in Korea.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Child; Child, Preschool; Clofarabine; Combined Modality Therapy; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Prospective Studies; Republic of Korea; Salvage Therapy; Survival Rate; Young Adult | 2021 |
Recurrent urinary tract infections and low secretory IgA following CD19-directed CAR T-cell therapy for relapsed acute lymphoblastic leukemia.
Topics: Antigens, CD19; Antimetabolites, Antineoplastic; B-Lymphocytes; Bacteriuria; Child; Clofarabine; Cytarabine; Escherichia coli; Escherichia coli Infections; Female; Humans; Immunoglobulin A, Secretory; Immunoglobulin G; Immunoglobulin M; Immunotherapy, Adoptive; Lymphocyte Count; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteus Infections; Proteus mirabilis; Urinary Tract Infections | 2018 |
Ponatinib-Induced Graft-versus-Host Disease/Graft-versus-Leukemia Effect in a Patient with Philadelphia-Positive Acute Lymphoblastic Leukemia without the T315I Mutation Relapsing after Allogeneic Transplant.
Topics: Adenine Nucleotides; Adult; Arabinonucleosides; Bone Marrow; Clofarabine; Cyclophosphamide; Disease-Free Survival; Female; Fusion Proteins, bcr-abl; Graft vs Host Disease; Humans; Imidazoles; Immunophenotyping; Mutation; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Protein Kinase Inhibitors; Pyridazines; Recurrence; Salvage Therapy; Transplantation, Homologous | 2017 |
Long-term Survival and Value of Chimeric Antigen Receptor T-Cell Therapy for Pediatric Patients With Relapsed or Refractory Leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Chronic Disease; Clofarabine; Cost-Benefit Analysis; Humans; Immunotherapy, Adoptive; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quality-Adjusted Life Years; Receptors, Antigen, T-Cell; Receptors, Chimeric Antigen; Recurrence; Treatment Outcome; Young Adult | 2018 |
[Therapeutic effect of clofarabine in children with relapsed or refractory acute lymphoblastic leukemia].
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Agents; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Female; Follow-Up Studies; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2013 |
Feasibility of clofarabine cytoreduction followed by haploidentical hematopoietic stem cell transplantation in patients with relapsed or refractory advanced acute leukemia.
Topics: Adenine Nucleotides; Adult; Aged; Arabinonucleosides; Clofarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Young Adult | 2013 |
A clofarabine-based bridging regimen in patients with relapsed ALL and persistent minimal residual disease (MRD).
Topics: Adenine Nucleotides; Adolescent; Antimetabolites, Antineoplastic; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Neoplasm Recurrence, Local; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Probability; Remission Induction; Time Factors; Treatment Outcome; Young Adult | 2014 |
Enhanced skin toxicity associated with the combination of clofarabine plus cytarabine for the treatment of acute leukemia.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies; Skin Diseases | 2014 |
Clofarabine/cyclophosphamide for debulking before stem cell transplantation.
Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Drug Administration Schedule; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Transplantation, Homologous; Treatment Outcome; Young Adult | 2014 |
Clofarabine-based combination chemotherapy for relapse and refractory childhood acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Adolescent; Analgesics, Opioid; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cefazolin; Child; Clofarabine; Cyclophosphamide; Etoposide; Fentanyl; Humans; Induction Chemotherapy; Male; Pain; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Shock, Septic; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2014 |
The potential of clofarabine in MLL-rearranged infant acute lymphoblastic leukaemia.
Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cell Line, Tumor; Cell Survival; Clofarabine; Cytarabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Synergism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Infant; Inhibitory Concentration 50; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; Tumor Cells, Cultured | 2015 |
Haploidentical Bone Marrow Transplantation With Clofarabine and Busulfan Conditioning for a Child With Multiple Recurrent Acute Lymphoblastic Leukemia.
Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Arabinonucleosides; Bone Marrow Transplantation; Busulfan; Child, Preschool; Clofarabine; Humans; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning; Transplantation, Homologous | 2016 |
Refractory acute lymphoblastic leukemia in Chinese children: bridging to stem cell transplantation with clofarabine, cyclophosphamide and etoposide.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Asian People; Child; Child, Preschool; Clofarabine; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Young Adult | 2016 |
The combination effects of bendamustine with antimetabolites against childhood acute lymphoblastic leukemia cells.
Topics: Adenine Nucleotides; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Bendamustine Hydrochloride; Cell Line, Tumor; Cell Proliferation; Child; Cladribine; Clofarabine; Cytarabine; Drug Administration Schedule; Drug Synergism; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 2016 |
Enhancement of the in vivo antitumor activity of clofarabine by 1-beta-D-[4-thio-arabinofuranosyl]-cytosine.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Drug Synergism; Drug Therapy, Combination; Humans; Mice; Mice, Nude; Mice, SCID; Neoplasms, Experimental; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2009 |
Clofarabine: a size that fits all, may not fit all.
Topics: Adenine Nucleotides; Arabinonucleosides; Clofarabine; Drug Administration Schedule; Humans; Leukemia; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2009 |
Diffusion-driven device for a high-resolution dose-response profiling of combination chemotherapy.
Topics: Adenine Nucleotides; Annexin A5; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cell Death; Clofarabine; Diffusion; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Fluorescent Dyes; Humans; Miniaturization; Phosphatidylserines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Toxicity Tests; Tumor Cells, Cultured | 2009 |
Advanced Philadelphia chromosome positive acute lymphoblastic leukemia patients relapsed after treatment with tyrosine-kinase inhibitors: successful response to clofarabine and cyclophosphamide.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Female; Humans; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Recurrence | 2009 |
Clofarabine-based salvage chemotherapy for relapsed or refractory acute leukemia before allogeneic stem cell transplantation: results from a case series.
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Male; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2009 |
Last exit clofarabine?
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Humans; Leukemia; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2009 |
Clofarabine-induced capillary leak syndrome in a child with refractory acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Capillary Leak Syndrome; Child; Clofarabine; Female; Hemofiltration; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2010 |
Remission re-induction chemotherapy with clofarabine, topotecan, thiotepa, and vinorelbine for patients with relapsed or refractory leukemia.
Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Thiotepa; Topotecan; Vinblastine; Vinorelbine | 2010 |
Nursing considerations for optimal outpatient management of adult patients with leukemia treated with clofarabine.
Topics: Adenine Nucleotides; Adult; Ambulatory Care; Antineoplastic Agents; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Humans; Monitoring, Physiologic; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2011 |
Early UK experience in the use of clofarabine in the treatment of relapsed and refractory paediatric acute lymphoblastic leukaemia.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Drug Evaluation; Female; Humans; Infant; Infant, Newborn; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome | 2011 |
Clofarabine-based chemotherapy for relapsed/refractory adult acute lymphoblastic leukemia and lymphoblastic lymphoma. The Spanish experience.
Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Male; Middle Aged; Off-Label Use; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Salvage Therapy; Spain; Young Adult | 2012 |
Clofarabine-containing conditioning regimen for allo-SCT in AML/ALL patients: a survey from the Acute Leukemia Working Party of EBMT.
Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Arabinonucleosides; Clofarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Stem Cell Transplantation; Transplantation Conditioning; Young Adult | 2012 |
Mechanisms of the apoptotic activity of Cl-F-araA in a human T-ALL cell line, CCRF-CEM.
Topics: Adenine Nucleotides; Apoptosis; Arabinonucleosides; cdc25 Phosphatases; Clofarabine; Down-Regulation; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 2002 |
Population pharmacokinetics of clofarabine, a second-generation nucleoside analog, in pediatric patients with acute leukemia.
Topics: Adenine Nucleotides; Adolescent; Adult; Arabinonucleosides; Child; Child, Preschool; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clofarabine; Computer Simulation; Half-Life; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Metabolic Clearance Rate; Models, Biological; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reproducibility of Results | 2004 |
Clofarabine.
Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Arabinonucleosides; Clofarabine; Drugs, Investigational; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2005 |
Clofarabine: in pediatric patients with acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Adolescent; Arabinonucleosides; Child; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clofarabine; Humans; Infant; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2005 |
In vitro cytotoxicity of nelarabine, clofarabine and flavopiridol in paediatric acute lymphoblastic leukaemia.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Burkitt Lymphoma; Child; Clofarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flavonoids; Humans; Inhibitory Concentration 50; Leukemia-Lymphoma, Adult T-Cell; Piperidines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 2007 |
Clofarabine induced durable complete remission in heavily pretreated adolescents with relapsed and refractory leukemia.
Topics: Acute Disease; Adenine Nucleotides; Adolescent; Arabinonucleosides; Clofarabine; Female; Humans; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 2007 |
Fatal skin and liver toxicity in a patient treated with clofarabine.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Child; Clofarabine; Fatal Outcome; Female; Humans; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Skin Diseases | 2008 |