Page last updated: 2024-09-03

clofarabine and Acute Disease

clofarabine has been researched along with Acute Disease in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (59.09)29.6817
2010's6 (27.27)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Alatrash, G; Alousi, AM; Anderlini, P; Bassett, R; Champlin, RE; Chen, J; Daher, M; Hosing, C; Kawedia, J; Kebriaei, P; Ledesma, C; Lu, Y; Marin, D; Mehta, R; Nieto, Y; Olson, A; Oran, B; Popat, U; Qazilbash, M; Rondon, G; Saberian, C; Shpall, EJ; Thall, PF; Valdez, BC1
Baruchel, A; Boƫlle-Le Corfec, E; Geffriaud-Ricouard, C; Goto, H; Jeha, S; Pieters, R; Shin, HY1
Borkhardt, A; Dilloo, D; Escherich, G; Faber, J; Feuchtinger, T; Horstmann, MA; Imschweiler, T; Jorch, N; Pekrun, A; Schmid, I; Schramm, F; Spohn, M; Zimmermann, M; Zur Stadt, U1
Boddy, N; Burrows, F; Pallis, M; Russell, N; Seedhouse, C; Whittall, A1
Boulad, F; Castro-Malaspina, H; Giralt, SA; Kernan, NA; Kobos, R; O'Reilly, RJ; Papadopoulos, EB; Perales, MA; Prockop, SE; Scaradavou, A; Spitzer, B; Webb, N; Young, JW; Zabor, EC1
Feldman, E; Ippoliti, C; James, S; Roboz, GJ; Savva, D; Thomas, CM; van Besien, K1
Badowska, W; Balcerska, A; Balwierz, W; Derwich, K; Gil, L; Komarnicki, M; Kowalczyk, J; Krawczuk-Rybak, M; Matysiak, M; Sobol, G; Sonta-Jakimczyk, D; Stefaniak, J; Styczynski, J; Urasinski, T; Wachowiak, J; Wieczorek, M; Wysocki, M1
Albano, E; Altman, A; Arceci, R; Bomgaars, L; Gaynon, P; Goldman, S; Jeha, S; Kadota, R; Luchtman-Jones, L; Razzouk, B; Rheingold, S; Ritchey, K; Rytting, M; Steinherz, L; Steinherz, P; Stine, K1
Abichandani, R; Barry, E; Carroll, WL; Chu, R; Cooper, T; Gaynon, P; Hijiya, N; Jeha, S; Kadota, R; Rytting, M; Shen, V; Silverman, L; Steinherz, P; Thomson, B1
Einsele, H; Grigoleit, GU; Kapp, M; Mielke, S; Stuhler, G; Tan, SM; Topp, MS; Unzicker, C1
Faderl, S1
Amin, C; Barr, ND; Chiu, WM; Foster, MC; Ivanova, A; Richards, KL; Shea, T; van Deventer, HW; Voorhees, PM; Whitman, J1
Barisone, E; Bertorello, N; Calvillo, M; De Rossi, G; Dufour, C; Lo Nigro, L; Luciani, M; Messina, C; Miano, M; Micalizzi, C; Parasole, R; Petruzziello, F; Pistorio, A; Putti, MC; Varotto, S; Ziino, O1
Abd Elmoneim, A; Arceci, RJ; Boklan, J; Cooper, T; Gore, L; Narendran, A; Ricklis, RM; Rolla, K; Scott, T1
Giles, FJ1
Estey, EH; Thall, PF1
Albertioni, F; Eriksson, S; Gruber, A; Karlsson, MO; Liliemark, J; Lindemalm, S; Wang, Y1
Beran, M; Bonate, P; Cortes, J; Du, M; Estey, E; Estrov, Z; Faderl, S; Ferrajoli, A; Gandhi, V; Garcia-Manero, G; Giles, FJ; Kantarjian, H; Keating, M; Kwari, M; O'Brien, S; Plunkett, W; Wierda, W1
Beran, M; Cortes, J; Estrov, Z; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Giles, FJ; Kantarjian, HM; Koller, C; Kwari, M; O'Brien, S; Ravandi, F; Verstovsek, S; Wierda, W1
Estey, EH1
Balakrishnan, K; Briel, J; Carraway, H; Gandhi, V; Gore, SD; Greer, J; Karp, JE; Levis, MJ; McDevitt, MA; Ricklis, RM; Smith, BD1
Jeha, S; Meyers, PA; Steinherz, LJ; Steinherz, PG1

Reviews

2 review(s) available for clofarabine and Acute Disease

ArticleYear
Patient-Level Meta-analysis of Clofarabine in Acute Lymphoblastic Leukemia.
    Advances in therapy, 2023, Volume: 40, Issue:12

    Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Clinical Trials, Phase II as Topic; Clofarabine; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

2023
New drugs in acute myeloid leukemia.
    Current oncology reports, 2002, Volume: 4, Issue:5

    Topics: Acute Disease; Adenine Nucleotides; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Bevacizumab; Boronic Acids; Bortezomib; Clofarabine; Cytosine; Decitabine; Dioxolanes; Humans; Indoles; Leukemia, Myeloid; Phthalazines; Pyrazines; Pyridines; Pyrroles; Thionucleotides

2002

Trials

11 trial(s) available for clofarabine and Acute Disease

ArticleYear
Vorinostat Combined with Busulfan, Fludarabine, and Clofarabine Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Leukemia: Long-Term Study Outcomes.
    Transplantation and cellular therapy, 2022, Volume: 28, Issue:8

    Topics: Acute Disease; Busulfan; Clofarabine; Drug Therapy, Combination; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Recurrence; Vidarabine; Vorinostat

2022
Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acut
    Haematologica, 2022, 05-01, Volume: 107, Issue:5

    Topics: Acute Disease; Antineoplastic Agents; Child; Clofarabine; Cytarabine; Disease-Free Survival; Humans; Lymphoma, Non-Hodgkin; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome

2022
Second Allogeneic Stem Cell Transplantation for Acute Leukemia Using a Chemotherapy-Only Cytoreduction with Clofarabine, Melphalan, and Thiotepa.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:8

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Adult; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Melphalan; Myeloablative Agonists; Remission Induction; Salvage Therapy; Survival Analysis; Thiotepa; Transplantation, Homologous; Young Adult

2016
Phase II study of clofarabine in pediatric patients with refractory or relapsed acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-10, Volume: 27, Issue:26

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Agents; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Drug Resistance, Neoplasm; Female; Fever; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Nausea; Neutropenia; Recurrence; Remission Induction; Treatment Outcome; Young Adult

2009
A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia.
    Leukemia, 2009, Volume: 23, Issue:12

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Salvage Therapy; Treatment Outcome; Young Adult

2009
A phase I dose-escalation study of clofarabine in combination with fractionated gemtuzumab ozogamicin in patients with refractory or relapsed acute myeloid leukemia.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:7

    Topics: Acute Disease; Adenine Nucleotides; Adult; Alanine Transaminase; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Aspartate Aminotransferases; Clofarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gemtuzumab; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Neutropenia; Recurrence; Survival Analysis; Treatment Outcome; Young Adult

2012
Clofarabine, cyclophosphamide and etoposide for the treatment of relapsed or resistant acute leukemia in pediatric patients.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:9

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Gastrointestinal Diseases; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Remission Induction; Treatment Outcome

2012
Phase I dose-escalation trial of clofarabine followed by escalating doses of fractionated cyclophosphamide in children with relapsed or refractory acute leukemias.
    Pediatric blood & cancer, 2012, Dec-15, Volume: 59, Issue:7

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; DNA Damage; Drug Administration Schedule; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Young Adult

2012
Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias.
    Blood, 2005, Feb-01, Volume: 105, Issue:3

    Topics: Acute Disease; Adenine Nucleotides; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Karyotyping; Leukemia; Male; Middle Aged; Recurrence; Treatment Outcome

2005
Clofarabine and cytarabine combination as induction therapy for acute myeloid leukemia (AML) in patients 50 years of age or older.
    Blood, 2006, Jul-01, Volume: 108, Issue:1

    Topics: Acute Disease; Adenine Nucleotides; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chromosome Aberrations; Clofarabine; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome

2006
A phase 1 clinical-laboratory study of clofarabine followed by cyclophosphamide for adults with refractory acute leukemias.
    Blood, 2007, Sep-15, Volume: 110, Issue:6

    Topics: Acute Disease; Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arabinonucleosides; Clofarabine; Cyclophosphamide; DNA Damage; DNA Repair; Female; Histones; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Recurrence, Local; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome

2007

Other Studies

9 other study(ies) available for clofarabine and Acute Disease

ArticleYear
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells.
    BMC pharmacology & toxicology, 2013, Jun-15, Volume: 14

    Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Azacitidine; Cell Line, Tumor; Cell Survival; Clofarabine; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Humans; Leukemia, Myeloid; Piperidines; Purines; RNA Polymerase II; RNA, Neoplasm; Roscovitine; Sirolimus; TOR Serine-Threonine Kinases

2013
Clofarabine as a bridge to hematopoietic stem cell transplant.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:1

    Topics: Acute Disease; Adenine Nucleotides; Adult; Aged; Antimetabolites, Antineoplastic; Arabinonucleosides; Clofarabine; Combined Modality Therapy; Female; Fever; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Survival Analysis

2017
Comparison of clofarabine activity in childhood and adult acute leukemia: individual tumor response study.
    Anticancer research, 2009, Volume: 29, Issue:5

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Adult; Antineoplastic Agents; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Humans; Infant; Leukemia; Middle Aged; Treatment Outcome; Young Adult

2009
Clofarabine-based salvage chemotherapy for relapsed or refractory acute leukemia before allogeneic stem cell transplantation: results from a case series.
    Leukemia & lymphoma, 2009, Volume: 50, Issue:12

    Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Male; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome

2009
Last exit clofarabine?
    Leukemia & lymphoma, 2009, Volume: 50, Issue:12

    Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Humans; Leukemia; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome

2009
New designs for phase 2 clinical trials.
    Blood, 2003, Jul-15, Volume: 102, Issue:2

    Topics: Acute Disease; Adenine Nucleotides; Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Bayes Theorem; Bias; Biomarkers; Clinical Trials, Phase II as Topic; Clofarabine; Confounding Factors, Epidemiologic; Cytarabine; Daunorubicin; Drug Carriers; False Negative Reactions; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid; Liposomes; Middle Aged; Patient Selection; Randomized Controlled Trials as Topic; Remission Induction; Research Design; Thalidomide; Topotecan; Treatment Outcome

2003
Comparison of cytotoxicity of 2-chloro- 2'-arabino-fluoro-2'-deoxyadenosine (clofarabine) with cladribine in mononuclear cells from patients with acute myeloid and chronic lymphocytic leukemia.
    Haematologica, 2003, Volume: 88, Issue:3

    Topics: Acute Disease; Adenine Nucleotides; Adult; Aged; Aged, 80 and over; Arabinonucleosides; Cell Survival; Cladribine; Clofarabine; Drug Evaluation; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukocytes, Mononuclear; Male; Middle Aged

2003
Advances in the management of AML in the elderly.
    Clinical advances in hematology & oncology : H&O, 2007, Volume: 5, Issue:3

    Topics: Acute Disease; Adenine Nucleotides; Aged; Antineoplastic Agents; Arabinonucleosides; Cause of Death; Clofarabine; Humans; Hydrazines; Leukemia, Myeloid; Sulfonamides

2007
Clofarabine induced durable complete remission in heavily pretreated adolescents with relapsed and refractory leukemia.
    Journal of pediatric hematology/oncology, 2007, Volume: 29, Issue:9

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Arabinonucleosides; Clofarabine; Female; Humans; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction

2007