clodronic acid has been researched along with Osteoarthritis in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Abdou, WM; Geronikaki, A; Kamel, AA | 1 |
| Casabella, A; Molfetta, L; Palermo, A; Rosini, S; Saviola, G | 1 |
| Gimigliano, F; Ilardi, W; Iolascon, G; Liguori, S; Moretti, A; Paoletta, M; Snichelotto, F; Toro, G | 1 |
| Abdi-Ali, L; Campostrini, L; Carbonare, LD; Povino, MR; Sacco, S; Saviola, G | 1 |
| Aikawa, J; Inoue, G; Iwabuchi, K; Iwase, D; Matsumoto, T; Minatani, A; Miyagi, M; Mukai, M; Satoh, M; Takano, S; Takaso, M; Uchida, K | 1 |
| Biotti, A; Bovi, M; Cheri, S; Dalle Carbonare, L; Deiana, M; Mottes, M; Perduca, M; Pisani, A; Valenti, MT | 1 |
| Bianchi, G; Cantarini, L; Dalle Carbonare, L; Frediani, B; Giusti, A; Malavolta, N; Molfetta, L; Saviola, G | 1 |
| Düsterdieck-Zellmer, KF | 1 |
| Aikawa, J; Fujimaki, H; Inoue, G; Iwabuchi, K; Minatani, A; Miyagi, M; Sato, M; Takano, S; Takaso, M; Uchida, K | 1 |
| Abdi-Ali, L; Baiardi, P; Benucci, M; Campostrini, L; Manfredi, M; Mannoni, A; Sacco, S; Saviola, G | 1 |
| Blom, AB; Holthuysen, AE; Nabbe, KC; Smeets, RL; van den Berg, WB; van der Kraan, P; van Lent, PL; van Rooijen, N; Vitters, E | 1 |
| Ceponis, A; Ding, Y; Konttinen, YT; Lindy, O; López-Otín, C; Santavirta, S; Sorsa, T | 1 |
| Doyle, DV; Dunn, CJ; Willoughby, DA | 1 |
3 review(s) available for clodronic acid and Osteoarthritis
| Article | Year |
|---|---|
Role of the Osteochondral Unit in the Pathogenesis of Osteoarthritis: Focus on the Potential Use of Clodronate.
Topics: Bone and Bones; Cartilage, Articular; Clodronic Acid; Humans; Inflammation; Osteoarthritis | 2022 |
The Rationale for the Intra-Articular Administration of Clodronate in Osteoarthritis.
Topics: Animals; Clodronic Acid; Disease Models, Animal; Humans; Injections, Intra-Articular; Mice; Osteoarthritis; Rabbits | 2021 |
Clodronate in the management of different musculoskeletal conditions.
Topics: Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Humans; Muscle Neoplasms; Musculoskeletal Diseases; Orthopedic Procedures; Osteoarthritis; Osteoporosis | 2018 |
2 trial(s) available for clodronic acid and Osteoarthritis
| Article | Year |
|---|---|
Intramuscular clodronate in erosive osteoarthritis of the hand is effective on pain and reduces serum COMP: a randomized pilot trial-The ER.O.D.E. study (ERosive Osteoarthritis and Disodium-clodronate Evaluation).
Topics: Aged; Analgesics; Anti-Inflammatory Agents; Antirheumatic Agents; Bone Density Conservation Agents; Cartilage Oligomeric Matrix Protein; Clodronic Acid; Diphosphonates; Female; Hand Joints; Humans; Injections, Intramuscular; Male; Middle Aged; Osteoarthritis; Pain; Pilot Projects; Single-Blind Method; Treatment Outcome | 2017 |
Clodronate and hydroxychloroquine in erosive osteoarthritis: a 24-month open randomized pilot study.
Topics: Aged; Antirheumatic Agents; Bone Density Conservation Agents; Clodronic Acid; Female; Hand Joints; Hand Strength; Health Status; Humans; Hydroxychloroquine; Hyperalgesia; Male; Middle Aged; Osteoarthritis; Pain; Pain Measurement; Pilot Projects; Treatment Failure; Treatment Outcome | 2012 |
8 other study(ies) available for clodronic acid and Osteoarthritis
| Article | Year |
|---|---|
Inhibitory effect of novel S,N-bisphosphonates on some carcinoma cell lines, osteoarthritis, and chronic inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Biological Assay; Cell Line, Tumor; Chronic Disease; Computer-Aided Design; Diphosphonates; Female; Granuloma; Humans; Inflammation; Male; Mice; Osteoarthritis; Rats; Structure-Activity Relationship; Toxicity Tests | 2012 |
Nerve growth factor regulation and production by macrophages in osteoarthritic synovium.
Topics: Aged; Aged, 80 and over; Animals; Cells, Cultured; Clodronic Acid; Disease Models, Animal; Female; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1beta; Lipopolysaccharide Receptors; Liposomes; Macrophages; Male; Mice; Nerve Growth Factor; Osteoarthritis; Osteoarthritis, Knee; Polymerase Chain Reaction; Synovial Membrane; Tumor Necrosis Factor-alpha | 2017 |
Clodronate as a Therapeutic Strategy against Osteoarthritis.
Topics: Aged; Biomarkers; Cell Differentiation; Cells, Cultured; Chondrocytes; Chondrogenesis; Clodronic Acid; Collagen Type II; Cytokines; Female; Humans; Middle Aged; Nanoparticles; Osteoarthritis; Pain; Severity of Illness Index; SOX9 Transcription Factor; Stem Cells; Up-Regulation | 2017 |
[Use of bisphosphonates in horses - a review].
Topics: Animals; Clodronic Acid; Diphosphonates; Horse Diseases; Horses; Osteoarthritis; Tarsal Bones | 2018 |
Synovial macrophage-derived IL-1β regulates the calcitonin receptor in osteoarthritic mice.
Topics: Animals; Antigens, Differentiation; Calcitonin Gene-Related Peptide; Calcitonin Receptor-Like Protein; Cells, Cultured; Clodronic Acid; Disease Models, Animal; Gene Expression Regulation; Humans; Interleukin-1beta; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Osteoarthritis; Receptor Activity-Modifying Protein 1; Receptors, Calcitonin; Signal Transduction; Synovial Membrane | 2016 |
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation.
Topics: Animals; Antimetabolites; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Cells, Cultured; Chondrocytes; Clodronic Acid; Liposomes; Macrophages; Mesoderm; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Osteoarthritis; Periosteum; Stem Cells; Synovial Membrane; Transforming Growth Factor beta | 2004 |
Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cartilage, Articular; Clodronic Acid; Collagenases; Diphosphonates; Female; Humans; Immunoblotting; Immunohistochemistry; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Middle Aged; Osteoarthritis; Pamidronate; Penicillamine; Recombinant Proteins; RNA, Messenger; Synovial Membrane | 1997 |
Potassium permanganate induced calcergy: a model to study the effects of drugs on hydroxyapatite crystal deposition.
Topics: Animals; Calcinosis; Clodronic Acid; Dexamethasone; Disease Models, Animal; Etidronic Acid; Hydroxyapatites; Indomethacin; Male; Osteoarthritis; Potassium Permanganate; Rats; Spectrophotometry, Infrared; Time Factors | 1979 |