clodronic acid has been researched along with Osteoarthritis of Knee in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Bailey, KN; Furman, BD; Guilak, F; Kimmerling, KA; Olson, SA; Wu, CL; Zeitlin, J | 1 |
| Cantarini, L; Conticini, E; Falsetti, P; Frediani, B; Giannotti, S; Migliore, A; Nicosia, A; Pierguidi, S; Toscano, C | 1 |
| Bonazzi, S; Casabella, A; Comini, L; Ferrari, P; Ghellere, F; Lul, AA; Molfetta, L; Niccolò, E; Saviola, G | 1 |
| Aikawa, J; Inoue, G; Iwabuchi, K; Iwase, D; Matsumoto, T; Minatani, A; Miyagi, M; Mukai, M; Satoh, M; Takano, S; Takaso, M; Uchida, K | 1 |
| Adami, S; Fracassi, E; Gatti, D; Idolazzi, L; Orsolini, G; Povino, MR; Rossini, M; Viapiana, O | 1 |
| Adami, S; Bianchi, G; Lapadula, G; Olivieri, I; Ramonda, R; Rossini, M; Viapiana, O | 1 |
| Iannitti, T; Palmieri, B; Rottigni, V | 1 |
| Blom, AB; Holthuysen, AE; Libregts, S; van den Berg, WB; van der Kraan, PM; van Lent, PL; van Rooijen, N | 1 |
4 trial(s) available for clodronic acid and Osteoarthritis of Knee
| Article | Year |
|---|---|
Intramuscular Clodronate in Long-Term Treatment of Symptomatic Knee Osteoarthritis: A Randomized Controlled Study.
Topics: Aged; Bone Density Conservation Agents; Clodronic Acid; Dose-Response Relationship, Drug; Female; Humans; Male; Osteoarthritis, Knee; Pain; Pain Measurement; Time Factors; Treatment Outcome | 2020 |
Effects of intra-articular clodronate in the treatment of knee osteoarthritis: results of a double-blind, randomized placebo-controlled trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Bone Density Conservation Agents; Clodronic Acid; Double-Blind Method; Female; Humans; Injections, Intra-Articular; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Treatment Outcome | 2015 |
Intra-articular clodronate for the treatment of knee osteoarthritis: dose ranging study vs hyaluronic acid.
Topics: Aged; Analysis of Variance; Bone Density Conservation Agents; Clodronic Acid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hyaluronic Acid; Injections, Intra-Articular; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Range of Motion, Articular; Treatment Outcome | 2009 |
Preliminary study of highly cross-linked hyaluronic acid-based combination therapy for management of knee osteoarthritis-related pain.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Blood Sedimentation; C-Reactive Protein; Clodronic Acid; Cross-Linking Reagents; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hyaluronic Acid; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Treatment Outcome | 2013 |
4 other study(ies) available for clodronic acid and Osteoarthritis of Knee
| Article | Year |
|---|---|
Intra-articular depletion of macrophages increases acute synovitis and alters macrophage polarity in the injured mouse knee.
Topics: Animals; Apoptosis; Calcium-Binding Proteins; Clodronic Acid; Genes, Transgenic, Suicide; Injections, Intra-Articular; Intra-Articular Fractures; Knee Injuries; Lectins, C-Type; Liposomes; Macrophages; Male; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Transgenic; Nitric Oxide Synthase Type II; Osteoarthritis, Knee; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Synovitis; Tacrolimus; X-Ray Microtomography | 2020 |
Use of clodronate for painful knee prosthesis in osteoarthritis patients: a 6-month pilot study.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Arthralgia; Arthroplasty, Replacement, Knee; Body Mass Index; Bone Density Conservation Agents; Clodronic Acid; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Knee Prosthesis; Male; Osteoarthritis, Knee; Pain Measurement; Pain, Postoperative; Pilot Projects; Prospective Studies; Regression Analysis; Time Factors | 2020 |
Nerve growth factor regulation and production by macrophages in osteoarthritic synovium.
Topics: Aged; Aged, 80 and over; Animals; Cells, Cultured; Clodronic Acid; Disease Models, Animal; Female; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1beta; Lipopolysaccharide Receptors; Liposomes; Macrophages; Male; Mice; Nerve Growth Factor; Osteoarthritis; Osteoarthritis, Knee; Polymerase Chain Reaction; Synovial Membrane; Tumor Necrosis Factor-alpha | 2017 |
Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3.
Topics: Animals; Arthritis, Experimental; Bone Density Conservation Agents; Cartilage, Articular; Clodronic Acid; Immunoenzyme Techniques; Macrophages; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Osteoarthritis, Knee; Peptide Fragments; Synovial Membrane | 2007 |