Page last updated: 2024-08-22

clodronic acid and Nerve Degeneration

clodronic acid has been researched along with Nerve Degeneration in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
El-Mufti, L; Han, X; Lan, X; Li, Q; Ren, H; Wang, J1
Hanlon, LA; Huh, JW; Raghupathi, R1
Cmarik, JL; Hanson, C; Li, X; Ruscetti, S1
Drabek, T; End, B; Jackson, EK; Janata, A; Janesko-Feldman, K; Kochanek, PM; Stezoski, J; Tisherman, SA; Vagni, VA; van Rooijen, N; Wilson, CD1
Biber, K; Boddeke, HW; Brouwer, N; Heinrich, A; Heppner, FL; Kälin, RE; Rooijen, Nv; Vinet, J; Weering, HR; Wegner, A1
Guan, Z; Huitinga, I; Popovich, PG; Stokes, BT; van Rooijen, N; Wei, P1
Liu, T; Tracey, DJ; van Rooijen, N1
Heyes, MP; Koennecke, LA; McAuliffe, MJ; McNally, B; van Rooijen, N; Zito, MA1

Other Studies

8 other study(ies) available for clodronic acid and Nerve Degeneration

ArticleYear
Microglial Depletion with Clodronate Liposomes Increases Proinflammatory Cytokine Levels, Induces Astrocyte Activation, and Damages Blood Vessel Integrity.
    Molecular neurobiology, 2019, Volume: 56, Issue:9

    Topics: Animals; Astrocytes; Blood Vessels; Clodronic Acid; Cytokines; Inflammation Mediators; Liposomes; Male; Mice, Inbred C57BL; Microglia; Neostriatum; Nerve Degeneration; Neuroglia; Up-Regulation

2019
Depletion of microglia immediately following traumatic brain injury in the pediatric rat: Implications for cellular and behavioral pathology.
    Experimental neurology, 2019, Volume: 316

    Topics: Analgesics, Non-Narcotic; Animals; Animals, Newborn; Behavior, Animal; Brain Injuries, Traumatic; Cerebral Cortex; Clodronic Acid; Female; Head Injuries, Closed; Male; Maze Learning; Memory; Microglia; Nerve Degeneration; Neurons; Psychomotor Performance; Rats; Rats, Sprague-Dawley; White Matter

2019
Neurodegeneration induced by PVC-211 murine leukemia virus is associated with increased levels of vascular endothelial growth factor and macrophage inflammatory protein 1 alpha and is inhibited by blocking activation of microglia.
    Journal of virology, 2009, Volume: 83, Issue:10

    Topics: Animals; Capillaries; Cells, Cultured; Cerebellum; Chemokine CCL3; Clodronic Acid; Demyelinating Diseases; Endothelium, Vascular; Inflammation; Leukemia Virus, Murine; Leukemia, Experimental; Microglia; Muscular Atrophy; Nerve Degeneration; Rats; Rats, Inbred F344; Retroviridae Infections; Tumor Virus Infections; Vascular Endothelial Growth Factor A

2009
Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats.
    Resuscitation, 2012, Volume: 83, Issue:4

    Topics: Animals; Cardiopulmonary Resuscitation; Cell Proliferation; Clodronic Acid; Disease Models, Animal; Heart Arrest; Hippocampus; Hypothermia, Induced; Injections, Intralesional; Liposomes; Male; Microglia; Nerve Degeneration; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Risk Assessment; Survival Rate

2012
Neuroprotective function for ramified microglia in hippocampal excitotoxicity.
    Journal of neuroinflammation, 2012, Jan-31, Volume: 9

    Topics: Animals; CD11b Antigen; Cell Death; Clodronic Acid; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Organ Culture Techniques; Phosphopyruvate Hydratase

2012
Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury.
    Experimental neurology, 1999, Volume: 158, Issue:2

    Topics: Animals; Axons; Clodronic Acid; Drug Carriers; Female; Hindlimb; Inflammation; Liposomes; Macrophages; Motor Activity; Nerve Degeneration; Rats; Rats, Inbred Lew; Spinal Cord; Spinal Cord Injuries

1999
Depletion of macrophages reduces axonal degeneration and hyperalgesia following nerve injury.
    Pain, 2000, Volume: 86, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Animals; Axons; Clodronic Acid; Drug Compounding; Hot Temperature; Hyperalgesia; Immunohistochemistry; Liposomes; Macrophages; Male; Nerve Degeneration; Pain Measurement; Rats; Rats, Wistar; Sciatic Neuropathy; Wallerian Degeneration

2000
Depletion of systemic macrophages by liposome-encapsulated clodronate attenuates striatal macrophage invasion and neurodegeneration following local endotoxin infusion in gerbils.
    Brain research, 2001, Feb-16, Volume: 892, Issue:1

    Topics: Analysis of Variance; Animals; Clodronic Acid; Corpus Striatum; Drug Carriers; Endotoxins; Gerbillinae; Infusions, Parenteral; Leukocytes; Lipopolysaccharides; Liposomes; Macrophages; Mice; Mice, Inbred C57BL; Nerve Degeneration; Salmonella

2001