Page last updated: 2024-08-22

clodronic acid and Multiple Myeloma

clodronic acid has been researched along with Multiple Myeloma in 78 studies

Research

Studies (78)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (11.54)	18.7374
1990's	29 (37.18)	18.2507
2000's	14 (17.95)	29.6817
2010's	24 (30.77)	24.3611
2020's	2 (2.56)	2.80

Authors

Authors	Studies
Chatziravdeli, V; Doxani, C; Katsaras, D; Katsaras, GN; Stefanidis, I; Zintzaras, E	1
Adhikari, M; Amorim, T; Anderson, J; Bellido, T; Boeckman, RK; Cregor, M; Cuevas, PL; Delgado-Calle, J; Ebetino, FH; Ferrari, AJ; Helms, JA; Khan, S; Kurihara, N; Lehal, R; McAndrews, K; Roodman, GD; Sabol, HM; Srinivasan, V; Vigolo, M	1
Djulbegovic, B; Kumar, A; Mhaskar, R; Miladinovic, B	1
Bell, SE; Cairns, DA; Child, JA; Cook, G; Davies, FE; Drayson, MT; Gregory, WM; Jackson, GH; Morgan, GJ; Owen, RG; Royle, KL	1
Clark, KC; Coulter, EA; Croucher, PI; Evdokiou, A; Hewett, DR; Mrozik, KM; Noll, JE; Opperman, KS; Psaltis, PJ; Schwarz, N; Vandyke, K; Zannettino, AC	1
Cavo, M; Dimopoulos, MA; Drake, MT; Durie, BG; García-Sanz, R; Jurczyszyn, A; Leleu, X; Lentzsch, S; Merlini, G; Morgan, G; Munshi, N; Raje, N; Rajkumar, SV; Reiman, T; Roodman, GD; Sezer, O; Shimizu, K; Spencer, A; Terpos, E; Turesson, I	1
Boccadoro, M; Brioli, A; Child, JA; Cook, G; Davies, FE; Drayson, MT; Gregory, WM; Jackson, GH; Larocca, A; Morgan, GJ; Owen, RG; Palumbo, A; Russell, N; Szubert, A; Wu, P	1
Brown, J; Fullarton, JR; Palmieri, C	1
Alegre, A; Bailén, A; Giraldo, P; Gironella, M	1
Ashcroft, AJ; Bell, SE; Boyd, KD; Byrne, J; Child, JA; Cook, G; Davies, FE; Drayson, MT; Feyler, S; Gregory, WM; Jackson, GH; Morgan, GJ; Navarro Coy, N; Osborne, WL; Owen, RG; Roddie, H; Ross, FM; Rudin, C; Szubert, AJ; Wu, P	1
Ashcroft, AJ; Bell, SE; Byrne, J; Child, JA; Cocks, K; Cook, G; Davies, FE; Drayson, MT; Feyler, S; Gregory, WM; Jackson, GH; Morgan, GJ; Navarro-Coy, N; Owen, RG; Roddie, H; Ross, F; Rudin, C; Szubert, AJ	1
Rajkumar, SV	1
Berenson, J; Dimopoulos, MA; Terpos, E	1
Morgan, GJ	2
Ludwig, H; Zojer, N	1
Kyrgidis, A; Tzellos, TG	1
Kami, M; Matayoshi, T; Takeuchi, K; Tanimoto, T; Yagasaki, F	1
Adam, Z; Hájek, R; Jakubcová, R; Klincová, M; Krejcí, M; Mayer, J; Pour, L; Szturz, P; Zahradová, L	1
Ashcroft, AJ; Bell, SE; Byrne, J; Child, JA; Cocks, K; Cook, G; Davies, FE; Drayson, MT; Feyler, S; Gregory, WM; Jackson, GH; Morgan, GJ; Navarro-Coy, N; Owen, RG; Roddie, H; Ross, FM; Rudin, C; Szubert, AJ; Wu, P	1
Dimopoulos, MA; Terpos, E	1
Anderson, KC; Ghobrial, IM; Laubach, JP; Mahindra, A; Mitsiades, CS; Munshi, N; Raje, N; Richardson, PG; Rosenblatt, J; Schlossman, RL	1
Berenson, JR	2
Bains, M; Chandiwana, D; Delea, TE; El Ouagari, K; Kaura, S; Morgan, GJ; Rotter, J; Taylor, M	1
Ashcroft, AJ; Bell, SE; Child, JA; Davies, FE; Drayson, MT; Gregory, WM; Jackson, GH; Morgan, GJ; Owen, RG; Szubert, AJ	1
Clark, OA; Djulbegovic, B; Glasmacher, A; Kumar, A; Mhaskar, R; Miladinovic, B; Redzepovic, J; Wheatley, K	1
Anderson, K; Berenson, JR; Biermann, JS; Hillner, BE; Kyle, RA; Lipton, A; Yee, GC	1
Adam, Z; Lastůvková, I	1
Ashcroft, AJ; Davies, FE; Morgan, GJ	1
Ben-Dor, D; Lugassy, G; Nahlieli, O; Nemets, A; Shaham, R	1
Bagis, B; Durmus, A; Saracoglu Tekin, U; Senel, FC	1
Al-Nawas, B; Grötz, KA; Küttner, C; Walter, C	1
Erskine, JG; McQuaker, IG; Montazeri, AH	1
Andriani, A; Barbarano, L; Bibas, M; Cafro, AM; D'Avanzo, G; Gaglioti, D; Morra, E; Nichelatti, M; Nosari, AM; Riva, F; Taroni, A	1
Briancon, D; Chapuy, MC; Charhon, S; Delmas, PD; Edouard, C; Meunier, PJ; Vignon, E	1
Kanis, JA; Paterson, AD; Russell, RG	1
Beard, DJ; Cameron, EC; Douglas, DL; Kanis, JA; Paterson, AD; Preston, FE; Russell, RG	1
Chantraine, A; Donath, A; Jung, A; Kitler, ME; Mermillod, B; Turnill, D; van Ouwenaller, C	1
Conte, N; Di Virgilio, R; Roiter, I	1
Raisz, LG	1
Baquiran, DC; Canfield, RE; Osserman, EF; Schlatterer, JP; Sherman, WH; Siris, ES	1
Irjala, K; Laakso, M; Lahtinen, R; Mattila, K; Pelliniemi, TT; Pulkki, K; Rajamäki, A; Tienhaara, A	1
Adam, Z; Hájek, D; Prokes, B; Vorlícek, J	1
Adam, Z; Hájek, D; Hájek, J; Hejlová, N; Mayer, J; Penka, M; Prokes, B; Tomíska, M; Vorlícek, J	1
Elomaa, I; Laakso, M; Lahtinen, R; Virkkunen, P	1
Wasan, HS; Waxman, J	1
Abdulkadyrov, KM; Bessmel'tsev, SS	2
Clemens, MR; Fessele, K; Heim, ME	1
Jantunen, E; Laakso, M; Lahtinen, R	2
Elomaa, I; Laakso, M; Lahtinen, R; Risteli, J; Risteli, L; Virkkunen, P	1
Ashley, S; Hanson, J; Kanis, JA; McCloskey, E; Paterson, AH; Powles, TJ	1
Bauduer, F; Delmer, A	1
Adam, Z; Hájek, D; Hejlová, N; Krejcí, M; Prokes, B; Vorlícek, J; Znojĭl, V	1
Braun, HJ; Deicher, H; Fett, W; Harms, P; Kindler, U; Klinkenstein, C; Peest, D; Planker, M; Schäfer, E; Schumacher, K; Siecke, H	1
Body, JJ; Coleman, RE; Piccart, M	1
Jantunen, E; Laakso, M	1
Cieslar, P; Hulejová, H; Klener, P; Slabý, J; Spacek, P; Spicka, I	1
Apperley, JF; Croucher, PI; Rogers, MJ; Russell, RG; Shipman, CM	1
Chapman, C; Drayson, MT; Dunn, J; Kanis, JA; MacLennan, IC; McCloskey, EV	1
Bloomfield, DJ	1
Lipton, A	1
Bartl, R; Body, JJ; Burckhardt, P; Delmas, PD; Diel, IJ; Fleisch, H; Kanis, JA; Kyle, RA; Mundy, GR; Paterson, AH; Rubens, RD	1
Musto, P	1
Bruce, NJ; Guest, JF; Kanis, JA; McCloskey, EV	1
Berthaud, P; Jadaud, E; Lortholary, A	1
Berenson, J; Hortobagyi, G; Lipton, A; Major, PP	1
Ranganath, L; Semple, MJ	1
Kanis, JA; McCloskey, EV	1
Clark, RE; Durham, BH; Flory, AJ; Fraser, WD; Ion, EM; Woodcock, BE	1
Adam, Z; Dusek, L; Hájek, R; Prokes, B; Tomíska, M; Vorlícek, J	1
Drayson, MT; Dunn, JA; Kanis, JA; MacLennan, IC; McCloskey, EV	1
Elomaa, I; Laakso, M; Lahtinen, R; Palva, I; Virkkunen, P	1
Delmas, PD	1
Ascari, E; Attardo-Parrinello, G; Merlini, G	1
Canfield, RE; Jacobs, TP; Siris, ES	1

Reviews

25 review(s) available for clodronic acid and Multiple Myeloma

Article	Year
A systematic review and meta-analysis of interventional studies of bisphosphonates and denosumab in multiple myeloma and future perspectives. Journal of musculoskeletal & neuronal interactions, 2022, 12-01, Volume: 22, Issue:4 Topics: Clodronic Acid; Denosumab; Diphosphonates; Humans; Multiple Myeloma; Zoledronic Acid	2022
Bisphosphonates in multiple myeloma: an updated network meta-analysis. The Cochrane database of systematic reviews, 2017, 12-18, Volume: 12 Topics: Antineoplastic Agents; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Diphosphonates; Disease-Free Survival; Etidronic Acid; Fractures, Bone; Humans; Imidazoles; Multiple Myeloma; Pamidronate; Randomized Controlled Trials as Topic; Spinal Fractures; Zoledronic Acid	2017
Comparative efficacy of bisphosphonates in metastatic breast and prostate cancer and multiple myeloma: a mixed-treatment meta-analysis. Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Dec-15, Volume: 19, Issue:24 Topics: Breast Neoplasms; Clodronic Acid; Diphosphonates; Female; Humans; Ibandronic Acid; Imidazoles; Male; Multiple Myeloma; Neoplasm Metastasis; Pamidronate; Prostatic Neoplasms; Zoledronic Acid	2013
Zoledronic acid in the management of bone disease as a consequence of multiple myeloma: a review. European journal of haematology, 2014, Volume: 92, Issue:3 Topics: Antineoplastic Agents; Bone Diseases; Clodronic Acid; Diphosphonates; Drug Monitoring; Humans; Ibandronic Acid; Imidazoles; Multiple Myeloma; Pamidronate; Zoledronic Acid	2014
Established role of bisphosphonate therapy for prevention of skeletal complications from myeloma bone disease. Critical reviews in oncology/hematology, 2011, Volume: 77 Suppl 1 Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Female; Humans; Imidazoles; Mice; Multiple Myeloma; Osteolysis; Pamidronate; Risk Factors; Spinal Cord Compression; Zoledronic Acid	2011
Can bisphosphonates improve outcomes in patients with newly diagnosed multiple myeloma? Critical reviews in oncology/hematology, 2011, Volume: 77 Suppl 1 Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Breast Neoplasms; Clodronic Acid; Diphosphonates; Drug Evaluation, Preclinical; Female; Humans; Imidazoles; Male; Mice; Multiple Myeloma; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Treatment Outcome; Zoledronic Acid	2011
Supportive therapy in multiple myeloma. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2011, Volume: 183 Topics: Anemia; Blood Transfusion; Bone Diseases; Calcitonin; Clodronic Acid; Diphosphonates; Erythropoietin; Fractures, Bone; Hematinics; Humans; Hypercalcemia; Imidazoles; Multiple Myeloma; Osteoporosis; Pamidronate; Recombinant Proteins; Renal Insufficiency; Zoledronic Acid	2011
The Medical Research Council Myeloma IX trial: the impact on treatment paradigms. European journal of haematology, 2012, Volume: 88, Issue:1 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Disease-Free Survival; Female; Humans; Imidazoles; Infusions, Intravenous; Male; Multiple Myeloma; Osteolysis; Practice Guidelines as Topic; Zoledronic Acid	2012
Bisphosphonates in multiple myeloma: a network meta-analysis. The Cochrane database of systematic reviews, 2012, May-16, Issue:5 Topics: Antineoplastic Agents; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Diphosphonates; Etidronic Acid; Fractures, Bone; Humans; Imidazoles; Multiple Myeloma; Pamidronate; Randomized Controlled Trials as Topic; Zoledronic Acid	2012
Aetiology of bone disease and the role of bisphosphonates in multiple myeloma. The Lancet. Oncology, 2003, Volume: 4, Issue:5 Topics: Antineoplastic Agents; Bone and Bones; Bone Density; Bone Neoplasms; Chemokines; Clinical Trials as Topic; Clodronic Acid; Cytokines; Diphosphonates; Humans; Hypercalcemia; Imidazoles; Multiple Myeloma; Osteolysis; Patient Selection; Treatment Outcome; Zoledronic Acid	2003
Use of clodronate in multiple myeloma. Leukemia & lymphoma, 1995, Volume: 19, Issue:3-4 Topics: Antimetabolites; Bone Diseases; Clodronic Acid; Controlled Clinical Trials as Topic; Humans; Hypercalcemia; Multicenter Studies as Topic; Multiple Myeloma; Osteolysis	1995
[Multiple myeloma and bone manifestations. Role of clodronate]. Bulletin du cancer, 1996, Volume: 83, Issue:7 Topics: Analgesics, Non-Narcotic; Bone Density; Bone Diseases; Clodronic Acid; Humans; Hypercalcemia; Magnetic Resonance Imaging; Multiple Myeloma; Osteolysis; Pain; Quality of Life; Radiography; Treatment Outcome	1996
[Skeletal bone lesion and the effectiveness of Bonephos (clodronate) in the comprehensive therapy of multiple myeloma]. Voprosy onkologii, 1996, Volume: 42, Issue:4 Topics: Antineoplastic Agents; Clodronic Acid; Combined Modality Therapy; Humans; Multiple Myeloma	1996
Use of bisphosphonates in cancer patients. Cancer treatment reviews, 1996, Volume: 22, Issue:4 Topics: Alendronate; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Multiple Myeloma; Osteolysis; Pain; Pamidronate; Structure-Activity Relationship	1996
Bisphosphonate therapy in multiple myeloma. Acta oncologica (Stockholm, Sweden), 1996, Volume: 35 Suppl 5 Topics: Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Humans; Multiple Myeloma; Pamidronate	1996
[Clodronate and myeloma]. Duodecim; laaketieteellinen aikakauskirja, 1995, Volume: 111, Issue:12 Topics: Bone Resorption; Clodronic Acid; Diphosphonates; Humans; Multiple Myeloma	1995
Bisphosphonates in multiple myeloma. Cancer, 1997, Oct-15, Volume: 80, Issue:8 Suppl Topics: Bone Diseases; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Multiple Myeloma; Pain; Pamidronate; Randomized Controlled Trials as Topic	1997
Should bisphosphonates be part of the standard therapy of patients with multiple myeloma or bone metastases from other cancers? An evidence-based review. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:3 Topics: Analgesics, Non-Narcotic; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Evidence-Based Medicine; Female; Humans; Male; Multiple Myeloma; Pain; Pamidronate; Practice Guidelines as Topic; Prostatic Neoplasms; Randomized Controlled Trials as Topic	1998
Aredia: the once-monthly infusion for the treatment of bone metastases. Current opinion in oncology, 1998, Volume: 10 Suppl 1 Topics: Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Drug Administration Schedule; Etidronic Acid; Female; Humans; Male; Multiple Myeloma; Osteoclasts; Pamidronate; Randomized Controlled Trials as Topic	1998
Current use of bisphosphonates in oncology. International Bone and Cancer Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:12 Topics: Analgesics, Non-Narcotic; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandronic Acid; Multiple Myeloma; Pain; Pamidronate	1998
The role of bisphosphonates for the treatment of bone disease in multiple myeloma. Leukemia & lymphoma, 1998, Volume: 31, Issue:5-6 Topics: Adult; Aged; Aged, 80 and over; Bone Remodeling; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Humans; Hypercalcemia; Male; Middle Aged; Multicenter Studies as Topic; Multiple Myeloma; Osteolysis; Palliative Care; Pamidronate; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome	1998
[Bisphosphonates and bone metastases]. Bulletin du cancer, 1999, Volume: 86, Issue:9 Topics: Antineoplastic Agents; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Male; Multiple Myeloma; Pain; Pamidronate; Prostatic Neoplasms; Randomized Controlled Trials as Topic	1999
Oral bisphosphonates: A review of clinical use in patients with bone metastases. Cancer, 2000, Jan-01, Volume: 88, Issue:1 Topics: Alendronate; Biological Availability; Bone Density; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Clodronic Acid; Diphosphonates; Double-Blind Method; Etidronic Acid; Humans; Ibandronic Acid; Imidazoles; Male; Multiple Myeloma; Pamidronate; Prostatic Neoplasms; Pyridines; Randomized Controlled Trials as Topic; Risedronic Acid; Zoledronic Acid	2000
Bisphosphonates in multiple myeloma. Cancer, 2000, Jun-15, Volume: 88, Issue:12 Suppl Topics: Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Multiple Myeloma; Pain; Pamidronate	2000
The use of clodronate in multiple myeloma. Bone, 1991, Volume: 12 Suppl 1 Topics: Antineoplastic Agents; Bone Resorption; Calcium; Clodronic Acid; Combined Modality Therapy; Double-Blind Method; Humans; Hypercalcemia; Lymphokines; Multiple Myeloma; Neoplasm Proteins; Osteoclasts; Osteolysis	1991

Trials

24 trial(s) available for clodronic acid and Multiple Myeloma

Article	Year
Quality of life during and following sequential treatment of previously untreated patients with multiple myeloma: findings of the Medical Research Council Myeloma IX randomised study. British journal of haematology, 2018, Volume: 182, Issue:6 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clodronic Acid; Consolidation Chemotherapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Longitudinal Studies; Maintenance Chemotherapy; Male; Middle Aged; Multiple Myeloma; Quality of Life; Remission Induction; Self Report; Surveys and Questionnaires; Thalidomide; Transplantation, Autologous; Young Adult; Zoledronic Acid	2018
The impact of response on bone-directed therapy in patients with multiple myeloma. Blood, 2013, Oct-24, Volume: 122, Issue:17 Topics: Adult; Antineoplastic Agents; Bone and Bones; Bone Density Conservation Agents; Clodronic Acid; Diphosphonates; Disease-Free Survival; Female; Humans; Imidazoles; Male; Middle Aged; Multiple Myeloma; Remission Induction; Stem Cell Transplantation; Transplantation, Autologous; Treatment Outcome; Zoledronic Acid	2013
Osteonecrosis of the jaw and renal safety in patients with newly diagnosed multiple myeloma: Medical Research Council Myeloma IX Study results. British journal of haematology, 2014, Volume: 166, Issue:1 Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Clodronic Acid; Diphosphonates; Drug Administration Schedule; England; Female; Follow-Up Studies; Humans; Imidazoles; Incidence; Male; Middle Aged; Multiple Myeloma; Osteolysis; Zoledronic Acid	2014
First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial. Lancet (London, England), 2010, Dec-11, Volume: 376, Issue:9757 Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Imidazoles; Infusions, Intravenous; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Odds Ratio; Proportional Hazards Models; Research Design; Treatment Outcome; United Kingdom; Zoledronic Acid	2010
Safety and efficacy of zoledronic acid in multiple myeloma. Lancet (London, England), 2011, Jun-25, Volume: 377, Issue:9784 Topics: Clodronic Acid; Diphosphonates; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Humans; Imidazoles; Incidence; Male; Multiple Myeloma; Osteonecrosis; Prognosis; Risk Assessment; Safety Management; Severity of Illness Index; Survival Analysis; Thromboembolism; Zoledronic Acid	2011
Safety and efficacy of zoledronic acid in multiple myeloma. Lancet (London, England), 2011, Jun-25, Volume: 377, Issue:9784 Topics: Clodronic Acid; Diphosphonates; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Imidazoles; Male; Multiple Myeloma; Osteonecrosis; Prognosis; Risk Assessment; Safety Management; Survival Analysis; Thromboembolism; Treatment Outcome; Zoledronic Acid	2011
Effects of zoledronic acid versus clodronic acid on skeletal morbidity in patients with newly diagnosed multiple myeloma (MRC Myeloma IX): secondary outcomes from a randomised controlled trial. The Lancet. Oncology, 2011, Volume: 12, Issue:8 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Clodronic Acid; Diphosphonates; Female; Fractures, Spontaneous; Humans; Imidazoles; Infusions, Intravenous; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; United Kingdom; Zoledronic Acid	2011
Effects of induction and maintenance plus long-term bisphosphonates on bone disease in patients with multiple myeloma: the Medical Research Council Myeloma IX Trial. Blood, 2012, Jun-07, Volume: 119, Issue:23 Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Diphosphonates; Female; Follow-Up Studies; Humans; Imidazoles; Induction Chemotherapy; Male; Middle Aged; Multiple Myeloma; Thalidomide; Zoledronic Acid	2012
Long-term effects of dichloromethylene diphosphonate (CI2MDP) on skeletal lesions in multiple myeloma. Metabolic bone disease & related research, 1982, Volume: 4, Issue:3 Topics: Biopsy; Bone and Bones; Bone Resorption; Calcium; Clodronic Acid; Diphosphonates; Humans; Hydroxyproline; Multiple Myeloma; Radiography; Skull	1982
Use of dichloromethylene diphosphonate in metastatic bone disease. The New England journal of medicine, 1983, Jun-23, Volume: 308, Issue:25 Topics: Bone Neoplasms; Bone Resorption; Calcium; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Double-Blind Method; Humans; Hypercalcemia; Multiple Myeloma; Osteolysis; Random Allocation	1983
Effects of dichloromethylene diphosphonate on skeletal mobilization of calcium in multiple myeloma. The New England journal of medicine, 1980, Feb-07, Volume: 302, Issue:6 Topics: Adult; Aged; Bone and Bones; Bone Resorption; Calcium; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Double-Blind Method; Drug Evaluation; Female; Humans; Hydroxyproline; Male; Middle Aged; Multiple Myeloma; Osteoclasts; Time Factors	1980
Immunoreactive interleukin-6 and acute phase proteins as prognostic factors in multiple myeloma. Finnish Leukemia Group. Blood, 1995, Feb-01, Volume: 85, Issue:3 Topics: Acute-Phase Proteins; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Calcium; Clodronic Acid; Creatinine; Female; Hemoglobins; Humans; Interleukin-6; Male; Melphalan; Middle Aged; Multiple Myeloma; Predictive Value of Tests; Prednisone; Prognosis; Regression Analysis; Risk Factors; Serum Albumin; Survival Rate; Uric Acid	1995
Subgroup and cost-benefit analysis of the Finnish multicentre trial of clodronate in multiple myeloma. Finnish Leukaemia Group. British journal of haematology, 1994, Volume: 87, Issue:4 Topics: Aged; Bone and Bones; Clodronic Acid; Cost-Benefit Analysis; Disease Progression; Double-Blind Method; Female; Health Care Costs; Humans; Male; Middle Aged; Multiple Myeloma; Osteolysis; Paraneoplastic Syndromes; Risk Factors	1994
Multiple myeloma: effect of daily dichloromethylene bisphosphonate on skeletal complications. Annals of hematology, 1993, Volume: 66, Issue:3 Topics: Adult; Aged; Analgesia; Bone Diseases; Bone Resorption; Calcium; Clodronic Acid; Female; Fractures, Bone; Humans; Hypercalcemia; Male; Melphalan; Middle Aged; Multiple Myeloma; Osteoporosis; Prednisolone; Prospective Studies	1993
Monitoring the action of clodronate with type I collagen metabolites in multiple myeloma. European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:7 Topics: Aged; Alkaline Phosphatase; Analgesics, Non-Narcotic; Biomarkers, Tumor; Clodronic Acid; Collagen; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Myeloma; Osteoblasts; Osteoclasts; Prognosis; Protein Precursors; Survival Rate	1996
Pyridinium cross-links in multiple myeloma: correlation with clinical parameters and use for monitoring of intravenous clodronate therapy--a pilot study of the German Myeloma Treatment Group (GMTG). European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers, Tumor; Bone Resorption; Clodronic Acid; Collagen; Collagen Type I; Humans; Middle Aged; Multiple Myeloma; Neoplasm Staging; Paraneoplastic Syndromes; Peptides; Pilot Projects	1996
[Effect of clodronate in patients with multiple myeloma. Evaluation of specific markers of bone resorption]. Casopis lekaru ceskych, 1997, Jan-22, Volume: 136, Issue:2 Topics: Adult; Aged; Amino Acids; Biomarkers; Bone Resorption; Clodronic Acid; Female; Humans; Male; Middle Aged; Multiple Myeloma	1997
Bisphosphonates in multiple myeloma. Cancer, 1997, Oct-15, Volume: 80, Issue:8 Suppl Topics: Bone Diseases; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Multiple Myeloma; Pain; Pamidronate; Randomized Controlled Trials as Topic	1997
A randomized trial of the effect of clodronate on skeletal morbidity in multiple myeloma. MRC Working Party on Leukaemia in Adults. British journal of haematology, 1998, Volume: 100, Issue:2 Topics: Aged; Analgesics, Non-Narcotic; Bone Diseases; Calcium; Clodronic Acid; Female; Fractures, Spontaneous; Humans; Hypercalcemia; Hypocalcemia; Male; Middle Aged; Multiple Myeloma; Pain; Treatment Outcome	1998
Bone mineral density in multiple myeloma patients after intravenous clodronate therapy. Acta medica Austriaca, 2001, Volume: 28, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Clodronic Acid; Female; Humans; Infusions, Intravenous; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Recombinant Proteins; Reference Values; Time Factors; Tomography, X-Ray Computed	2001
Long-term follow-up of a prospective, double-blind, placebo-controlled randomized trial of clodronate in multiple myeloma. British journal of haematology, 2001, Volume: 113, Issue:4 Topics: Aged; Analgesics, Non-Narcotic; Chi-Square Distribution; Clodronic Acid; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multiple Myeloma; Prognosis; Prospective Studies; Regression Analysis; Spinal Fractures; Survival Analysis	2001
Randomised, placebo-controlled multicentre trial of clodronate in multiple myeloma. Finnish Leukaemia Group. Lancet (London, England), 1992, Oct-31, Volume: 340, Issue:8827 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Diseases; Calcium; Clodronic Acid; Double-Blind Method; Female; Follow-Up Studies; Fractures, Spontaneous; Humans; Hypercalcemia; Male; Middle Aged; Multiple Myeloma; Pain; Placebos	1992
The use of clodronate in multiple myeloma. Bone, 1991, Volume: 12 Suppl 1 Topics: Antineoplastic Agents; Bone Resorption; Calcium; Clodronic Acid; Combined Modality Therapy; Double-Blind Method; Humans; Hypercalcemia; Lymphokines; Multiple Myeloma; Neoplasm Proteins; Osteoclasts; Osteolysis	1991
Dichloromethylene diphosphonate action in hematologic and other malignancies. Bone, 1987, Volume: 8 Suppl 1 Topics: Administration, Oral; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Female; Humans; Hydroxyproline; Hypercalcemia; Infusions, Intravenous; Leukemia, Lymphoid; Male; Multiple Myeloma; Neoplasms; Pain	1987

Other Studies

31 other study(ies) available for clodronic acid and Multiple Myeloma

Article	Year
Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity. Cancer research, 2021, 10-01, Volume: 81, Issue:19 Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Bone Marrow Cells; Cell Line, Tumor; Clodronic Acid; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Humans; Mice; Multiple Myeloma; Osteolysis; Receptors, Notch; Signal Transduction; X-Ray Microtomography; Xenograft Model Antitumor Assays	2021
Clodronate-Liposome Mediated Macrophage Depletion Abrogates Multiple Myeloma Tumor Establishment In Vivo. Neoplasia (New York, N.Y.), 2019, Volume: 21, Issue:8 Topics: Animals; Biomarkers; Bone Density Conservation Agents; Cell Count; Cell Line, Tumor; Cell Movement; Clodronic Acid; Disease Models, Animal; Disease Susceptibility; Immunophenotyping; Liposomes; Macrophages; Mice; Multiple Myeloma; Osteoblasts; Tumor Microenvironment	2019
International Myeloma Working Group recommendations for the treatment of multiple myeloma-related bone disease. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jun-20, Volume: 31, Issue:18 Topics: Administration, Intravenous; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Combined Modality Therapy; Diphosphonates; Drug Therapy, Combination; Fractures, Bone; Humans; Imidazoles; International Cooperation; Magnetic Resonance Imaging; Medical Oncology; Multiple Myeloma; Osteonecrosis; Outcome Assessment, Health Care; Pamidronate; Positron-Emission Tomography; Practice Guidelines as Topic; Radiotherapy; Tomography, X-Ray Computed; Zoledronic Acid	2013
Zoledronic acid in myeloma: MRC Myeloma IX. Lancet (London, England), 2010, Dec-11, Volume: 376, Issue:9757 Topics: Administration, Oral; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Drug Administration Schedule; Humans; Imidazoles; Infusions, Intravenous; Multiple Myeloma; Pamidronate; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Zoledronic Acid	2010
[Regression of an osteolytic lesion in a patient with multiple myeloma treated with clodronate after a successful therapy with bortezomib-based regimen]. Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2011, Volume: 24, Issue:3 Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Boronic Acids; Bortezomib; Clodronic Acid; Femur; Humans; Male; Multiple Myeloma; Osteolysis; Pyrazines; Radiography; Recurrence; Remission Induction	2011
Zoledronic acid for all patients with newly diagnosed multiple myeloma? The Lancet. Oncology, 2011, Volume: 12, Issue:8 Topics: Bone Density Conservation Agents; Clodronic Acid; Diphosphonates; Female; Fractures, Spontaneous; Humans; Imidazoles; Male; Multiple Myeloma; Zoledronic Acid	2011
Further analyses of the Myeloma IX Study. Lancet (London, England), 2011, Aug-27, Volume: 378, Issue:9793 Topics: Bone Density Conservation Agents; Clodronic Acid; Diphosphonates; Humans; Imidazoles; Multiple Myeloma; Osteonecrosis; Thrombosis; Zoledronic Acid	2011
The Medical Research Council Myeloma IX Trial: new clinical insights on the anticancer effects of zoledronic acid in patients with multiple myeloma. Clinical lymphoma, myeloma & leukemia, 2012, Volume: 12, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Clodronic Acid; Diphosphonates; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Imidazoles; Male; Middle Aged; Multiple Myeloma; Randomized Controlled Trials as Topic; Treatment Outcome; Zoledronic Acid	2012
Cost-effectiveness of zoledronic acid vs clodronic acid for newly-diagnosed multiple myeloma from the United Kingdom healthcare system perspective. Journal of medical economics, 2012, Volume: 15, Issue:3 Topics: Bone Density Conservation Agents; Clodronic Acid; Cost-Benefit Analysis; Delivery of Health Care; Diphosphonates; Humans; Imidazoles; Models, Economic; Multiple Myeloma; Quality-Adjusted Life Years; Survival Analysis; United Kingdom; Zoledronic Acid	2012
American Society of Clinical Oncology clinical practice guidelines: the role of bisphosphonates in multiple myeloma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Sep-01, Volume: 20, Issue:17 Topics: Clodronic Acid; Diphosphonates; Drug Monitoring; Humans; Imidazoles; Multiple Myeloma; Osteolysis; Pamidronate; Zoledronic Acid	2002
[A questionnaire survey of tolerance and adverse effects of clodronate (Bonefos) in patients with multiple myeloma]. Vnitrni lekarstvi, 2002, Volume: 48, Issue:11 Topics: Administration, Oral; Adult; Aged; Clodronic Acid; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Multiple Myeloma; Surveys and Questionnaires	2002
Severe osteomyelitis of the jaw in long-term survivors of multiple myeloma: a new clinical entity. The American journal of medicine, 2004, Sep-15, Volume: 117, Issue:6 Topics: Actinomyces; Actinomycosis; Aged; Antimetabolites; Clodronic Acid; Female; Humans; Jaw; Male; Middle Aged; Multiple Myeloma; Necrosis; Osteomyelitis; Osteonecrosis; Severity of Illness Index; Survivors	2004
Severe osteomyelitis of the mandible associated with the use of non-nitrogen-containing bisphosphonate (disodium clodronate): report of a case. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2007, Volume: 65, Issue:3 Topics: Actinomycosis; Aged; Bone Density Conservation Agents; Clodronic Acid; Female; Humans; Mandibular Diseases; Multiple Myeloma; Osteomyelitis; Osteonecrosis; Tooth Extraction	2007
[Relevance of bisphosphonate long-term therapy in radiation therapy of endosteal jaw metastases]. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2007, Volume: 183, Issue:4 Topics: Bone Density Conservation Agents; Breast Neoplasms; Clodronic Acid; Female; Humans; Jaw Neoplasms; Middle Aged; Multiple Myeloma; Osteotomy	2007
Oral sodium clodronate induced osteonecrosis of the jaw in a patient with myeloma. European journal of haematology, 2007, Volume: 79, Issue:1 Topics: Adult; Clodronic Acid; Humans; Jaw Diseases; Male; Multiple Myeloma; Osteonecrosis	2007
Osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates: definition and management of the risk related to zoledronic acid. Clinical lymphoma & myeloma, 2008, Volume: 8, Issue:2 Topics: Aged; Aged, 80 and over; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Diphosphonates; Female; Humans; Imidazoles; Male; Mandible; Maxilla; Middle Aged; Multiple Myeloma; Necrosis; Zoledronic Acid	2008
The use of diphosphonates in myeloma. British journal of haematology, 1983, Volume: 53, Issue:4 Topics: Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Multiple Myeloma	1983
The use of dichloromethylene diphosphonate for the management of hypercalcaemia in multiple myeloma. British journal of haematology, 1983, Volume: 54, Issue:1 Topics: Aged; Alkaline Phosphatase; Calcium; Clodronic Acid; Creatinine; Diphosphonates; Female; Humans; Hydroxyproline; Hypercalcemia; Male; Middle Aged; Multiple Myeloma; Osteitis Deformans	1983
[Hypercalcemic crises of myelomatous origin. Treatment with dichloromethylene diphosphonate]. Presse medicale (Paris, France : 1983), 1984, Nov-24, Volume: 13, Issue:42 Topics: Aged; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Male; Multiple Myeloma; Paraneoplastic Syndromes	1984
New diphosphonates to block bone resorption. The New England journal of medicine, 1980, Feb-07, Volume: 302, Issue:6 Topics: Animals; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Double-Blind Method; Etidronic Acid; Humans; Hypercalcemia; Hyperparathyroidism; Multiple Myeloma; Osteitis Deformans; Osteoclasts; Osteolysis; Osteomalacia; Propanolamines	1980
Increasing bone density in myeloma patients after the administration of clodronate. Acta medica Austriaca, 1995, Volume: 22, Issue:1-2 Topics: Aged; Bone Density; Clodronic Acid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Middle Aged; Multiple Myeloma; Osteolysis; Palliative Care; Tomography, X-Ray Computed	1995
[Increased bone density in patients with multiple myeloma treated with clodronate]. Vnitrni lekarstvi, 1994, Volume: 40, Issue:11 Topics: Bone Density; Clodronic Acid; Female; Humans; Male; Middle Aged; Multiple Myeloma	1994
Clodronate for multiple myeloma. Lancet (London, England), 1993, Jan-16, Volume: 341, Issue:8838 Topics: Calcium; Clodronic Acid; Humans; Multiple Myeloma; Treatment Outcome	1993
[The use of the preparation bonefos in the combined therapy of multiple myeloma patients]. Terapevticheskii arkhiv, 1993, Volume: 65, Issue:12 Topics: Aged; Analgesics; Capsules; Clodronic Acid; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multiple Myeloma; Remission Induction; Time Factors	1993
Role of bisphosphonates in prevention and treatment of bone metastases from breast cancer. The Canadian journal of oncology, 1995, Volume: 5 Suppl 1 Topics: Analgesics, Non-Narcotic; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Hypercalcemia; Multiple Myeloma; Osteoporosis; Pain; Pamidronate	1995
[The effect of clodronate on bone density in patients with multiple myeloma--a 2-year follow-up of therapeutic effects]. Vnitrni lekarstvi, 1996, Volume: 42, Issue:6 Topics: Adult; Aged; Bone Density; Clodronic Acid; Diphosphonates; Female; Follow-Up Studies; Humans; Hypercalcemia; Male; Middle Aged; Multiple Myeloma; Osteolysis	1996
Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity. British journal of haematology, 1997, Volume: 98, Issue:3 Topics: Apoptosis; Clodronic Acid; Diphosphonates; DNA, Neoplasm; Humans; Multiple Myeloma; Pamidronate; Tumor Cells, Cultured	1997
Economic impact of using clodronate in the management of patients with multiple myeloma. British journal of haematology, 1999, Volume: 104, Issue:2 Topics: Clodronic Acid; Cost-Benefit Analysis; Drug Costs; Fractures, Bone; Health Resources; Humans; Multiple Myeloma; Recurrence; Sensitivity and Specificity; Survival Analysis	1999
Hypercalcaemia in a 63 year old man. Postgraduate medical journal, 2000, Volume: 76, Issue:895 Topics: Anti-Inflammatory Agents; Calcium-Binding Proteins; Clodronic Acid; Diphosphonates; Drug Resistance; Humans; Hypercalcemia; Male; Middle Aged; Multiple Myeloma	2000
Biochemical markers of bone turnover following high-dose chemotherapy and autografting in multiple myeloma. Blood, 2000, Oct-15, Volume: 96, Issue:8 Topics: Adult; Aged; Alkaline Phosphatase; Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bone Remodeling; Bone Resorption; Carmustine; Clodronic Acid; Combined Modality Therapy; Cytarabine; Disease Progression; Female; Hematopoietic Stem Cell Transplantation; Humans; Isoenzymes; Male; Melphalan; Middle Aged; Multiple Myeloma; Osteoclasts; Peptide Fragments; Podophyllotoxin; Procollagen; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome	2000
Treatment of painful bone lesions and hypercalcemia. European journal of haematology. Supplementum, 1989, Volume: 51 Topics: Bone Diseases; Clodronic Acid; Diphosphonates; Drug Evaluation; Humans; Hypercalcemia; Multiple Myeloma; Pain; Pilot Projects	1989