clodronic acid has been researched along with Lung Neoplasms in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 11 (61.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aghaei, M; Downey, CM; Jirik, FR; Schwendener, RA | 1 |
| Cao, N; Du, GJ; Geng, SN; Guo, ZZ; Han, G; Li, GG; Lin, HH; Ma, XF; Meng, MJ; Zheng, YQ | 1 |
| Drexel, C; Gress, TM; Griesmann, H; Michl, P; Milosevic, N; Rosendahl, J; Sipos, B | 1 |
| Benner, A; Berthel, A; Brand, K; Buechler, MW; Falk, CS; Grabe, N; Halama, N; Herrmann, T; Jaeger, D; Kahlert, C; Klupp, F; Koch, M; Krauss, J; Kunz, C; Lasitschka, F; Lerchl, T; Luckner-Minden, C; Luecke, S; Schneider, M; Springfeld, C; Suarez-Carmona, M; Suetterlin, T; Ulrich, A; Weitz, J; Zitvogel, L; Zoernig, I | 1 |
| Berry, G; Burt, BM; Engleman, E; Kheradmand, F; Lee, HS; Sugarbaker, DJ; Wang, DH; Wheeler, TM; Yoon, D | 1 |
| Colarusso, C; Pinto, A; Popolo, A; Sorrentino, R; Terlizzi, M | 1 |
| Fotovati, A; Hiraoka, K; Hosoi, F; Iguchi, H; Kimura, YN; Kuwano, M; Nagata, K; Ono, M; Osada, H; Shoda, T; Watari, K; Zenmyo, M | 1 |
| Kong, LQ; Sun, HC; Tang, ZY; Wang, L; Wu, WZ; Xiong, YQ; Xu, HX; Zhang, W; Zhu, XD; Zhuang, PY | 1 |
| Åkerud, P; Botling, J; Buysschaert, I; Carmeliet, P; Claesson-Welsh, L; Costa, S; Coulon, C; De Mol, M; De Palma, M; Dewerchin, M; Dresselaer, T; Himmelreich, U; Johansson, I; Knevels, E; Laoui, D; Larsson, E; Li, X; Mazzone, M; Phillipson, M; Rolny, C; Salomäki, H; Segura, I; Squadrito, ML; Tugues, S; Van Ginderachter, JA; Vinckier, S; Wyns, S | 1 |
| Freel Meyers, CL; Hann, CL; Rudek, MA; Webster, MR; Zhao, M | 1 |
| Said, N; Sanchez-Carbayo, M; Smith, SC; Theodorescu, D | 1 |
| Balsari, A; Bonecchi, R; Calvaruso, M; Colombo, MP; Meini, A; Piconese, S; Sfondrini, L; Sommariva, M; Tagliabue, E; Tortoreto, M; Van Rooijen, N; Zaffaroni, N | 1 |
| Khuri, F; Saba, N | 1 |
| Conroy, M; Cree, IA; Fernando, A; Knight, LA; Kurbacher, CM; Polak, M | 1 |
| Garraffo, C; Girlando, A; Malaponte, G; Mazzarino, C; Monte, V; Nicosia, A; Tantillo, F | 1 |
| Fotovati, A; Hosoi, F; Iguchi, H; Izumi, H; Kimura, YN; Kohno, K; Kuwano, M; Ono, M; Shirouzu, K; Takamori, S; Umezawa, K; Watari, K; Yasumoto, K | 1 |
| Liippo, K; Puolijoki, H | 1 |
| Fritze, D; Harjung, H | 1 |
1 review(s) available for clodronic acid and Lung Neoplasms
| Article | Year |
|---|---|
The role of bisphosphonates in the management of advanced cancer with a focus on non-small-cell lung cancer. Part 1: Mechanisms of action, role of biomarkers and preclinical applications.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Clodronic Acid; Diphosphonates; Etidronic Acid; False Negative Reactions; Fluorodeoxyglucose F18; Humans; Ibandronic Acid; Imidazoles; Lung Neoplasms; Pamidronate; Positron-Emission Tomography; Predictive Value of Tests; Therapeutic Equivalency; Zoledronic Acid | 2005 |
17 other study(ies) available for clodronic acid and Lung Neoplasms
| Article | Year |
|---|---|
DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarization.
Topics: Adenocarcinoma; Animals; Carcinoma, Non-Small-Cell Lung; Cell Membrane Permeability; Cell Polarity; Clodronic Acid; Humans; Inflammation; Liposomes; Lung Neoplasms; Macrophages; Male; Membrane Proteins; Mice, Transgenic; Necrosis; Neovascularization, Pathologic; Nucleotides, Cyclic; Phenotype; ras Proteins; Subcutaneous Tissue; Tumor Suppressor Protein p53; Xanthones; Xenograft Model Antitumor Assays | 2014 |
The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Apoptosis; Autophagy; Benzofurans; Capillary Permeability; Carcinogenesis; Carcinoma, Lewis Lung; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chick Embryo; Chloroquine; Clodronic Acid; Culture Media, Conditioned; Endothelial Cells; Female; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Macrophages; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neovascularization, Pathologic; Phosphoproteins; Trans-Activators; Urethane | 2016 |
Pharmacological macrophage inhibition decreases metastasis formation in a genetic model of pancreatic cancer.
Topics: Animals; Antineoplastic Agents; CD11b Antigen; CD4-Positive T-Lymphocytes; Cell Proliferation; Clodronic Acid; Interleukin-2 Receptor alpha Subunit; Liposomes; Liver Neoplasms; Lung Neoplasms; Macrophages; Mice; Models, Genetic; Neoplasms, Experimental; Neovascularization, Pathologic; Pancreatic Neoplasms; T-Lymphocytes; Tumor Burden; Vascular Endothelial Growth Factor A | 2017 |
Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients.
Topics: Adenocarcinoma; Apoptosis; Chemokine CCL5; Chemokines; Chemotaxis; Clinical Trials, Phase I as Topic; Clodronic Acid; Colorectal Neoplasms; Cyclohexanes; Humans; Interferon-alpha; Liver Neoplasms; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Macrophages; Maraviroc; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; NG-Nitroarginine Methyl Ester; Phenylurea Compounds; Pilot Projects; Pyridines; Receptors, CCR5; STAT3 Transcription Factor; Survival Analysis; Triazoles; Tumor Cells, Cultured; Tumor Microenvironment | 2016 |
Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Immunological; Cetuximab; Clodronic Acid; Cytokines; Disease Progression; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-1; Genes, Synthetic; Humans; Lung Neoplasms; Macrophage Activation; Macrophages, Alveolar; Mice; Mice, Transgenic; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Protein Kinase Inhibitors; Recombinant Fusion Proteins; Smoking; Uteroglobin | 2017 |
IL-1α and IL-1β-producing macrophages populate lung tumor lesions in mice.
Topics: Adenosine Triphosphate; Animals; Bronchoalveolar Lavage Fluid; Calpain; Carcinogenesis; Caspase 1; Caspase Inhibitors; Caspases; Caspases, Initiator; Cells, Cultured; Clodronic Acid; Dipeptides; Female; Glyburide; Inflammasomes; Interleukin-1alpha; Interleukin-1beta; Lipopolysaccharides; Lung Neoplasms; Macrophages, Alveolar; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Specific Pathogen-Free Organisms; Toll-Like Receptor 4 | 2016 |
Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages.
Topics: Animals; Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Disease Models, Animal; Female; Humans; Lung Neoplasms; Macrophages; Mice; Mice, Inbred BALB C; Monocytes; Muscle Neoplasms; Neoplasm Invasiveness; Pyrans; Spiro Compounds | 2008 |
Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects.
Topics: Angiogenesis Inhibitors; Animals; Benzenesulfonates; Carcinoma, Hepatocellular; Cell Line, Tumor; Clodronic Acid; Diphosphonates; Drug Therapy, Combination; Humans; Imidazoles; Liposomes; Liver Neoplasms, Experimental; Lung Neoplasms; Macrophages; Male; Mice; Mice, Nude; Niacinamide; Phenylurea Compounds; Pyridines; Sorafenib; Xenograft Model Antitumor Assays; Zoledronic Acid | 2010 |
HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.
Topics: Animals; Antibodies; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Chemotactic Factors; Clodronic Acid; Culture Media, Conditioned; Cytokines; Dendritic Cells; Down-Regulation; Endothelial Cells; Gene Expression; Humans; Hypoxia; Lung Neoplasms; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Microvessels; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Placenta Growth Factor; Pregnancy Proteins; Proteins; Regional Blood Flow; Transfection | 2011 |
Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cells.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Cell Survival; Clodronic Acid; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Organophosphorus Compounds; Prodrugs; Structure-Activity Relationship | 2011 |
RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration.
Topics: Animals; Carcinoma, Transitional Cell; Cell Line, Tumor; Chemokine CCL2; Clodronic Acid; Coculture Techniques; Female; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Dissociation Inhibitors; Humans; Inflammation; Kaplan-Meier Estimate; Lung Neoplasms; Macrophages; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasm Transplantation; Prognosis; Protein Isoforms; Tumor Microenvironment; U937 Cells; Urinary Bladder Neoplasms; Versicans | 2012 |
Anti-tumor activity of CpG-ODN aerosol in mouse lung metastases.
Topics: Aerosols; Animals; Antineoplastic Agents; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Clodronic Acid; Dendritic Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-12 Subunit p40; Interleukin-1beta; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Oligodeoxyribonucleotides | 2013 |
Pilot studies of the effect of zoledronic acid (Zometa) on tumor-derived cells ex vivo in the ATP-based tumor chemosensitivity assay.
Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Alendronate; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Caspase 3; Caspase 7; Caspases; Cell Line, Tumor; Cell Survival; Cisplatin; Clodronic Acid; Diphosphonates; Energy Metabolism; Female; Humans; Imidazoles; Inhibitory Concentration 50; Lung Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neoplasms, Unknown Primary; Ovarian Neoplasms; Paclitaxel; Tumor Cells, Cultured; Zoledronic Acid | 2005 |
Interleukin-2 receptors in patients with lung carcinoma metastasis undergoing treatment with disodium-clodronate. Preliminary research.
Topics: Bone Density Conservation Agents; Clodronic Acid; DNA, Neoplasm; Enzyme-Linked Immunosorbent Assay; Humans; Lung Neoplasms; Neoplasm Metastasis; Radioligand Assay; Receptors, Interleukin-2; Thymidine | 1989 |
Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis.
Topics: Animals; Cell Division; Cell Line, Tumor; Clodronic Acid; Drug Synergism; Humans; Inflammation; Interleukin-1beta; Lung Neoplasms; Macrophages; Male; Mice; Mice, Inbred C57BL; Neoplasms; Neovascularization, Pathologic; Transplantation, Heterologous; U937 Cells | 2007 |
Symptomatic hypercalcaemia in lung cancer.
Topics: Aged; Clodronic Acid; Humans; Hypercalcemia; Lung Neoplasms; Male; Middle Aged; Pilot Projects | 1992 |
[Monotherapy with clodronate for tumor-induced hypercalcemia].
Topics: Aged; Breast Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clodronic Acid; Diphosphonates; Female; Humans; Hypercalcemia; Leiomyosarcoma; Lung Neoplasms; Male; Middle Aged; Neoplasms; Pancreatic Neoplasms; Plasmacytoma; Uterine Neoplasms | 1990 |