Page last updated: 2024-08-22

clodronic acid and Liver Steatosis

clodronic acid has been researched along with Liver Steatosis in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's7 (70.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Ashida, K; Hasuzawa, N; Kabashima, M; Moriyama, Y; Nagayama, A; Nomura, M; Ogawa, Y; Tatsushima, K; Tokubuchi, R; Wang, L1
Cani, PD; Horsmans, Y; Lanthier, N; Lebrun, V; Leclercq, IA; Molendi-Coste, O; Sempoux, C; Stärkel, P; van Rooijen, N1
Akiyoshi, K; Aoe, S; Fukaishi, T; Hamaguchi, M; Itoh, M; Kanai, S; Kato, H; Komohara, Y; Konuma, K; Marumoto, Y; Ogawa, Y; Sakaida, I; Sakugawa, H; Suganami, T; Takeya, M; Terai, S1
Clementi, AH; Gaudy, AM; Mooney, RA; Pierce, RH; van Rooijen, N1
Cani, PD; Horsmans, Y; Lanthier, N; Leclercq, IA; Molendi-Coste, O; van Rooijen, N2
Feng, B; Jiao, P; Jun, D; Kim, T; Nie, Y; van Rooijen, N; Xu, H; Yang, Z1
Berk, M; Dixon, LJ; Feldstein, AE; Papouchado, BG; Thapaliya, S1
Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Tsai, TH; Yang, YY1
Adegboyega, P; Allman, M; Rivera, CA; Tagalicud, A; van Rooijen, N; Wallace, M1

Other Studies

10 other study(ies) available for clodronic acid and Liver Steatosis

ArticleYear
Clodronate, an inhibitor of the vesicular nucleotide transporter, ameliorates steatohepatitis and acute liver injury.
    Scientific reports, 2021, 03-04, Volume: 11, Issue:1

    Topics: Adenosine Triphosphate; Animals; Chemical and Drug Induced Liver Injury; Clodronic Acid; Diet; Disease Models, Animal; Fatty Liver; Humans; Inflammation; Lipopolysaccharides; Mice; Nucleotide Transport Proteins; Receptors, Purinergic

2021
Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice.
    Clinical science (London, England : 1979), 2013, Volume: 125, Issue:11

    Topics: Alcohol Drinking; Animals; Blood Glucose; Clodronic Acid; Fatty Liver; Female; Glucose; Homeostasis; Hydroxides; Insulin Resistance; Kupffer Cells; Macrophage Activation; Mice; Mice, Inbred C57BL; Oxidative Stress; Peroxisome Proliferators; PPAR alpha; Pyrimidines

2013
Hepatic crown-like structure: a unique histological feature in non-alcoholic steatohepatitis in mice and humans.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Chronic Disease; Clodronic Acid; Fatty Liver; Female; Hepatitis, Viral, Human; Humans; Inflammation; Lipid Metabolism; Liposomes; Liver; Liver Cirrhosis; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Non-alcoholic Fatty Liver Disease; Phenotype; Receptor, Melanocortin, Type 4

2013
Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling.
    Biochimica et biophysica acta, 2009, Volume: 1792, Issue:11

    Topics: Adipose Tissue; Animals; Bone Density Conservation Agents; Clodronic Acid; Diet; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Inflammation Mediators; Insulin; Insulin Resistance; Interleukin-10; Interleukin-6; Kupffer Cells; Liposomes; Macrophages; Male; Mice; Obesity; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, Insulin; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Triglycerides

2009
Kupffer cell activation is a causal factor for hepatic insulin resistance.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:1

    Topics: Adipose Tissue; Animals; Clodronic Acid; Dietary Fats; Drug Delivery Systems; Fatty Liver; Glucose Clamp Technique; Hepatitis; Hyperinsulinism; Injections, Intravenous; Insulin; Insulin Resistance; Kupffer Cells; Liposomes; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; Signal Transduction

2010
Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:12

    Topics: Adipose Tissue; Adiposity; Animals; Clodronic Acid; Diet, High-Fat; Fatty Liver; Inflammation; Insulin Resistance; Kupffer Cells; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity

2011
Clodronate liposomes improve metabolic profile and reduce visceral adipose macrophage content in diet-induced obese mice.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Adipose Tissue; Animals; Blood Glucose; Body Weight; Clodronic Acid; Coculture Techniques; Diet; Fatty Liver; Glucose Tolerance Test; Humans; Insulin; Liposomes; Liver; Macrophages; Male; Metabolome; Mice; Mice, Inbred C57BL; Mice, Obese; Organ Size; Stromal Cells; Triglycerides; Viscera

2011
Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis.
    Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:5

    Topics: Actins; Animals; Antigens, Differentiation; Caspase 1; Caspase 3; Choline Deficiency; Clodronic Acid; Collagen Type I; Fatty Liver; Hepatic Stellate Cells; Hepatocytes; Inflammation; Interleukin-1beta; Kupffer Cells; LIM Domain Proteins; Liver; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Nuclear Proteins; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2012
Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis.
    Clinical science (London, England : 1979), 2012, Volume: 123, Issue:12

    Topics: Analysis of Variance; Animals; Arachidonic Acid; Benzofurans; Choline; Clodronic Acid; Diet, High-Fat; DNA Primers; Fatty Acids, Unsaturated; Fatty Liver; Gadolinium; Hemodynamics; Hypertension, Portal; Insulin Resistance; Kupffer Cells; Leptin; Methionine; Methoxamine; Microcirculation; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Receptors, Thromboxane A2, Prostaglandin H2; RNA, Messenger; Sulfonylurea Compounds; Thiobarbituric Acid Reactive Substances; Thromboxane A2

2012
Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis.
    Journal of hepatology, 2007, Volume: 47, Issue:4

    Topics: Animals; Choline Deficiency; Clodronic Acid; Collagen Type I; Collagen Type I, alpha 1 Chain; Diet; Endotoxemia; Fatty Liver; Hepatitis, Animal; Kupffer Cells; Lymphotoxin-alpha; Methionine; Mice; Mice, Mutant Strains; PPAR alpha; Signal Transduction; Toll-Like Receptor 4; Triglycerides

2007
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